Validation study of a Finnish version of the Western Ontario and McMasters University osteoarthritis index von Soininen, J.V., Paavolainen, P.O., Gronblad, M.A., Kaapa, E.H.

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Validation study of a Finnish version of the Western Ontario and McMasters University osteoarthritis index von Soininen, J V, Paavolainen, P O, Gronblad, M A, Kaapa, E H

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Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation von Bis, Joshua C., Jian, Xueqiu, Kunkle, Brian W., Chen, Yuning, Hamilton-Nelson, Kara L., Bush, William S., Salerno, William J., Lancour, Daniel, Ma, Yiyi, Renton, Alan E., Marcora, Edoardo, Farrell, John J., Zhao, Yi, Qu, Liming, Ahmad, Shahzad, Amin, Najaf, Amouyel, Philippe, Beecham, Gary W., Below, Jennifer E., Campion, Dominique, Cantwell, Laura, Charbonnier, Camille, Chung, Jaeyoon, Crane, Paul K., Cruchaga, Carlos, Cupples, L. Adrienne, Dartigues, Jean-François, Debette, Stéphanie, Deleuze, Jean-François, Fulton, Lucinda, Gabriel, Stacey B., Genin, Emmanuelle, Gibbs, Richard A., Goate, Alison, Grenier-Boley, Benjamin, Gupta, Namrata, Haines, Jonathan L., Havulinna, Aki S., Helisalmi, Seppo, Hiltunen, Mikko, Howrigan, Daniel P., Ikram, M. Arfan, Kaprio, Jaakko, Konrad, Jan, Kuzma, Amanda, Lander, Eric S., Lathrop, Mark, Lehtimäki, Terho, Lin, Honghuang, Mattila, Kari, Mayeux, Richard, Muzny, Donna M., Nasser, Waleed, Neale, Benjamin, Nho, Kwangsik, Nicolas, Gaël, Patel, Devanshi, Pericak-Vance, Margaret A., Perola, Markus, Psaty, Bruce M., Quenez, Olivier, Rajabli, Farid, Redon, Richard, Reitz, Christiane, Remes, Anne M., Salomaa, Veikko, Sarnowski, Chloe, Schmidt, Helena, Schmidt, Michael, Schmidt, Reinhold, Soininen, Hilkka, Thornton, Timothy A., Tosto, Giuseppe, Tzourio, Christophe, van der Lee, Sven J., van Duijn, Cornelia M., Valladares, Otto, Vardarajan, Badri, Wang, Li-San, Wang, Weixin, Wijsman, Ellen, Wilson, Richard K., Witten, Daniela, Worley, Kim C., Zhang, Xiaoling, Bellenguez, Celine, Lambert, Jean-Charles, Kurki, Mitja I., Palotie, Aarno, Daly, Mark, Boerwinkle, Eric, Lunetta, Kathryn L., Destefano, Anita L., Dupuis, Josée, Martin, Eden R., Schellenberg, Gerard D., Seshadri, Sudha, Naj, Adam C., Fornage, Myriam, Farrer, Lindsay A.

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Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness von Lebedev, A V, Westman, E, Van Westen, G J P, Kramberger, M G, Lundervold, A, Aarsland, D, Soininen, H, Kłoszewska, I, Mecocci, P, Tsolaki, M, Vellas, B, Lovestone, S, Simmons, A

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Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease von Steinberg, Stacy, Stefansson, Hreinn, Jonsson, Thorlakur, Johannsdottir, Hrefna, Ingason, Andres, Helgason, Hannes, Sulem, Patrick, Magnusson, Olafur Th, Gudjonsson, Sigurjon A, Unnsteinsdottir, Unnur, Kong, Augustine, Helisalmi, Seppo, Soininen, Hilkka, Lah, James J, Aarsland, Dag, Fladby, Tormod, Ulstein, Ingun D, Djurovic, Srdjan, Sando, Sigrid B, White, Linda R, Knudsen, Gun-Peggy, Westlye, Lars T, Selbæk, Geir, Giegling, Ina, Hampel, Harald, Hiltunen, Mikko, Levey, Allan I, Andreassen, Ole A, Rujescu, Dan, Jonsson, Palmi V, Bjornsson, Sigurbjorn, Snaedal, Jon, Stefansson, Kari

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Metabolic profiling of polycystic ovary syndrome reveals interactions with abdominal obesity von Couto Alves, A, Valcarcel, B, Mäkinen, V-P, Morin-Papunen, L, Sebert, S, Kangas, A J, Soininen, P, Das, S, De Iorio, M, Coin, L, Ala-Korpela, M, Järvelin, M-R, Franks, S

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CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings von SEPPÄLÄ, T. T, NERG, O, JÄÄSKELÄINEN, J. E, RINNE, J, SOININEN, H, LEINONEN, V, HERUKKA, S.-K, KOIVISTO, A. M, RUMMUKAINEN, J, PULI, L, ZETTERBERG, H, PYYKKÖ, O. T, HELISALMI, S, ALAFUZOFF, I, HILTUNEN, M

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Evidence of effects of herbivory on Arctic vegetation: a systematic map protocol von Soininen, E. M, Barrio, I, Jepsen, J. U, Ehrich, D, Ravolainen, V. T, Speed, J. D. M

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Heparan Sulfate in Perlecan Promotes Mouse Atherosclerosis: Roles in Lipid Permeability, Lipid Retention, and Smooth Muscle Cell Proliferation von Tran-Lundmark, Karin, Tran, Phan-Kiet, Paulsson-Berne, Gabrielle, Fridén, Vincent, Soininen, Raija, Tryggvason, Karl, Wight, Thomas N, Kinsella, Michael G, Borén, Jan, Hedin, Ulf

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Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci von TUKIAINEN, Taru, KETTUNEN, Johannes, POUTA, Anneli, JULA, Antti, LEHTIMÄKI, Terho, KÄHÖNEN, Mika, VIIKARI, Jorma, TASKINEN, Marja-Riitta, JAUHIAINEN, Matti, ERIKSSON, Johan G, RAITAKARI, Olli, SALOMAA, Veikko, KANGAS, Antti J, JÄRVELIN, Marjo-Riitta, PEROLA, Markus, PALOTIE, Aarno, ALA-KORPELA, Mika, RIPATTI, Samuli, LYYTIKÄINEN, Leo-Pekka, SOININEN, Pasi, SARIN, Antti-Pekka, TIKKANEN, Emmi, O'REILLY, Paul F, SAVOLAINEN, Markku J, KASKI, Kimmo

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5-Year health-related quality of life outcome in patients with idiopathic normal pressure hydrocephalus von Junkkari, A., Sintonen, H., Danner, N., Jyrkkänen, H. K., Rauramaa, T., Luikku, A. J., Koivisto, A. M., Roine, R. P., Viinamäki, H., Soininen, H., Jääskeläinen, J. E., Leinonen, V.

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Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates von Wang, Qin, Kangas, Antti J, Soininen, Pasi, Tiainen, Mika, Tynkkynen, Tuulia, Puukka, Katri, Ruokonen, Aimo, Viikari, Jorma, Kähönen, Mika, Lehtimäki, Terho, Salomaa, Veikko, Perola, Markus, Davey Smith, George, Raitakari, Olli T, Järvelin, Marjo-Riitta, Würtz, Peter, Kettunen, Johannes, Ala-Korpela, Mika

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Post-mortem findings in 10 patients with presumed normal-pressure hydrocephalus and review of the literature von Leinonen, V., Koivisto, A. M., Savolainen, S., Rummukainen, J., Sutela, A., Vanninen, R., Jääskeläinen, J. E., Soininen, H., Alafuzoff, I.

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Metabolome in progression to Alzheimer's disease von Orešič, M, Hyötyläinen, T, Herukka, S-K, Sysi-Aho, M, Mattila, I, Seppänan-Laakso, T, Julkunen, V, Gopalacharyulu, P V, Hallikainen, M, Koikkalainen, J, Kivipelto, M, Helisalmi, S, Lötjönen, J, Soininen, H

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Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype von Vermunt, Lisa, Sikkes, Sietske A.M., van den Hout, Ardo, Handels, Ron, Bos, Isabelle, van der Flier, Wiesje M., Kern, Silke, Ousset, Pierre-Jean, Maruff, Paul, Skoog, Ingmar, Verhey, Frans R.J., Freund-Levi, Yvonne, Tsolaki, Magda, Wallin, Åsa K., Olde Rikkert, Marcel, Soininen, Hilkka, Spiru, Luisa, Zetterberg, Henrik, Blennow, Kaj, Scheltens, Philip, Muniz-Terrera, Graciela, Visser, Pieter Jelle, Vellas, B., Reynish, E., Ousset, P.J., Andrieu, S., Burns, A., Pasquier, F., Frisoni, G., Salmon, E., Michel, J.P., Zekry, D.S., Boada, M., Dartigues, J.F., Olde-Rikkert, M.G.M., Rigaud, A.S., Winblad, B., Malick, A., Sinclair, A., Frölich, L., Scheltens, P., Ribera, C., Touchon, J., Robert, P., Salva, A., Waldemar, G., Bullock, R., Tsolaki, M., Rodriguez, G., Spiru, L., Jones, R.W., Stiens, G., Stoppe, G., Eriksdotter Jönhagen, M., Cherubini, A., Lage, P.M., Gomez-Isla, T., Camus, V., Agüera-Morales, E., Lopez, F., Savy, S., Cantet, C., Coley, N.

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Biotic interactions mediate patterns of herbivore diversity in the Arctic von Barrio, I. C., Bueno, C. G., Gartzia, M., Soininen, E. M., Christie, K. S., Speed, J. D. M., Ravolainen, V. T., Forbes, B. C., Gauthier, G., Horstkotte, T., Hoset, K. S., Høye, T. T., Jónsdóttir, I. S., Lévesque, E., Mörsdorf, M. A., Olofsson, J., Wookey, P. A., Hik, D. S.

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Differential Associations of IL-4 With Hippocampal Subfields in Mild Cognitive Impairment and Alzheimer's Disease von Boccardi, Virginia, Westman, Eric, Pelini, Luca, Lindberg, Olof, Muehlboeck, J-Sebastian, Simmons, Andrew, Tarducci, Roberto, Floridi, Piero, Chiarini, Pietro, Soininen, Hilkka, Kloszewska, Iwona, Tsolaki, Magda, Vellas, Bruno, Spenger, Christian, Wahlund, Lars-Olof, Lovestone, Simon, Mecocci, Patrizia

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Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes von Wang, Qingbo, Pierce-Hoffman, Emma, Cummings, Beryl B., Alföldi, Jessica, Francioli, Laurent C., Gauthier, Laura D., Hill, Andrew J., O’Donnell-Luria, Anne H., Karczewski, Konrad J., MacArthur, Daniel G.

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease von Sims, Rebecca, Gerrish, Amy, Abraham, Richard, Hamshere, Marian L, Moskvina, Valentina, Jones, Nicola, Thomas, Charlene, Widdowson, Caroline, Chapman, Jade, Powell, John, Proitsi, Petroula, Lupton, Michelle K, Gill, Michael, Lawlor, Brian, Passmore, Peter A, Craig, David, McGuinness, Bernadette, Todd, Stephen, Mann, David, Smith, A David, Warden, Donald, Kehoe, Patrick G, Hardy, John, Mead, Simon, Collinge, John, Maier, Wolfgang, Schürmann, Britta, Heun, Reiner, Kölsch, Heike, van den Bussche, Hendrik, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Gallacher, John, Hüll, Michael, Rujescu, Dan, Giegling, Ina, Goate, Alison M, Kauwe, John S K, Nowotny, Petra, Morris, John C, Bettens, Karolien, Engelborghs, Sebastiaan, Deloukas, Panagiotis, Al-Chalabi, Ammar, Shaw, Christopher E, Tsolaki, Magda, Guerreiro, Rita, Klopp, Norman, Wichmann, H-Erich, Barcikowska, Maria, Wszolek, Zbigniew K, Dickson, Dennis W, van Duijn, Cornelia M, Breteler, Monique M B, Ikram, M Arfan, Fitzpatrick, Annette L, Seshadri, Sudha, Berr, Claudine, Epelbaum, Jacques, Dartigues, Jean-François, Tzourio, Christophe, Feulner, Thomas M, Riehle, Caterina, Krawczak, Michael, Mayhaus, Manuel, Nicolhaus, S, Steinberg, Stacy, Stefansson, Hreinn, Stefansson, Kari, Snædal, Jon, Björnsson, Sigurbjörn, Chouraki, Vincent, Zelenika, Diana, Delepine, Marc, Pasquier, Florence, Porcellini, Elisa, Hanon, Olivier, Alvarez, Victoria, Bosco, Paolo, Siciliano, Gabriele, Solfrizzi, Vincenzo, Bossù, Paola, Piccardi, Paola, Seripa, Davide, Pilotto, Alberto, Scarpini, Elio, Brice, Alexis, Hannequin, Didier, Jones, Lesley, Holmans, Peter A, Jonsson, Thorlakur, Morgan, Kevin, Younkin, Steven G, Owen, Michael J, O'Donovan, Michael, Amouyel, Philippe, Williams, Julie

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The effect of LRRK2 loss-of-function variants in humans von Whiffin, Nicola, Armean, Irina M., Kleinman, Aaron, Marshall, Jamie L., Minikel, Eric V., Goodrich, Julia K., Quaife, Nicholas M., Cole, Joanne B., Wang, Qingbo, Karczewski, Konrad J., Cummings, Beryl B., Francioli, Laurent, Laricchia, Kristen, Guan, Anna, Alipanahi, Babak, Morrison, Peter, Baptista, Marco A. S., Merchant, Kalpana M., Ware, James S., Havulinna, Aki S., Iliadou, Bozenna, Lee, Jung-Jin, Nadkarni, Girish N., Whiteman, Cole, Daly, Mark, Esko, Tõnu, Hultman, Christina, Loos, Ruth J. F., Milani, Lili, Palotie, Aarno, Pato, Carlos, Pato, Michele, Saleheen, Danish, Sullivan, Patrick F., Alföldi, Jessica, Cannon, Paul, MacArthur, Daniel G.

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