The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling von Sodhi, Chhinder P., Wipf, Peter, Yamaguchi, Yukihiro, Fulton, William B., Kovler, Mark, Niño, Diego F., Zhou, Qinjie, Banfield, Emilyn, Werts, Adam D., Ladd, Mitchell R., Buck, Rachael H., Goehring, Karen C., Prindle, Thomas, Wang, Sanxia, Jia, Hongpeng, Lu, Peng, Hackam, David J.

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Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis von Egan, Charlotte E, Sodhi, Chhinder P, Good, Misty, Lin, Joyce, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Ma, Congrong, Branca, Maria F, Weyandt, Samantha, Fulton, William B, Niño, Diego F, Prindle, Jr, Thomas, Ozolek, John A, Hackam, David J

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A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice von Sodhi, Chhinder P, Nguyen, Jenny, Yamaguchi, Yukihiro, Werts, Adam D, Lu, Peng, Ladd, Mitchell R, Fulton, William B, Kovler, Mark L, Wang, Sanxia, Prindle, Jr, Thomas, Zhang, Yong, Lazartigues, Eric D, Holtzman, Michael J, Alcorn, John F, Hackam, David J, Jia, Hongpeng

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Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors von Neal, Matthew D, Jia, Hongpeng, Eyer, Benjamin, Good, Misty, Guerriero, Christopher J, Sodhi, Chhinder P, Afrazi, Amin, Prindle, Jr, Thomas, Ma, Congrong, Branca, Maria, Ozolek, John, Brodsky, Jeffrey L, Wipf, Peter, Hackam, David J

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The human milk oligosaccharide 2′-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine von Good, Misty, Sodhi, Chhinder P., Yamaguchi, Yukihiro, Jia, Hongpeng, Lu, Peng, Fulton, William B., Martin, Laura Y., Prindle, Thomas, Nino, Diego F., Zhou, Qinjie, Ma, Congrong, Ozolek, John A., Buck, Rachael H., Goehring, Karen C., Hackam, David J.

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Necrotizing enterocolitis, gut microbes, and sepsis von Duess, Johannes W., Sampah, Maame E., Lopez, Carla M., Tsuboi, Koichi, Scheese, Daniel J., Sodhi, Chhinder P., Hackam, David J.

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Precision-based modeling approaches for necrotizing enterocolitis von Kovler, Mark L., Sodhi, Chhinder P., Hackam, David J.

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Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis von Lu, Peng, Yamaguchi, Yukihiro, Fulton, William B., Wang, Sanxia, Zhou, Qinjie, Jia, Hongpeng, Kovler, Mark L., Salazar, Andres Gonzalez, Sampah, Maame, Prindle, Thomas, Wipf, Peter, Sodhi, Chhinder P., Hackam, David J.

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Mechanisms of gut barrier failure in the pathogenesis of necrotizing enterocolitis: Toll-like receptors throw the switch von Hackam, David J., MD, PhD, Good, Misty, MD, Sodhi, Chhinder P., PhD

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Mucosa-associated bacterial diversity in necrotizing enterocolitis von Brower-Sinning, Rachel, Zhong, Diana, Good, Misty, Firek, Brian, Baker, Robyn, Sodhi, Chhinder P, Hackam, David J, Morowitz, Michael J

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A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair von Leaphart, Cynthia L, Cavallo, Jaime, Gribar, Steven C, Cetin, Selma, Li, Jun, Branca, Maria F, Dubowski, Theresa D, Sodhi, Chhinder P, Hackam, David J

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Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling von Yazji, Ibrahim, Sodhi, Chhinder P., Lee, Elizabeth K., Good, Misty, Egan, Charlotte E., Afrazi, Amin, Neal, Matthew D., Jia, Hongpeng, Lin, Joyce, Ma, Congrong, Branca, Maria F., Prindle, Thomas, Richardson, Ward M., Ozolek, John, Billiar, Timothy R., Binion, David G., Gladwin, Mark T., Hackam, David J.

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The role of epithelial Toll-like receptor signaling in the pathogenesis of intestinal inflammation von Gribar, Steven C., Anand, Rahul J., Sodhi, Chhinder P., Hackam, David J.

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Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis von Afrazi, Amin, Branca, Maria F., Sodhi, Chhinder P., Good, Misty, Yamaguchi, Yukihiro, Egan, Charlotte E., Lu, Peng, Jia, Hongpeng, Shaffiey, Shahab, Lin, Joyce, Ma, Congrong, Vincent, Garrett, Thomas, Prindle, Weyandt, Samantha, Neal, Matthew D., Ozolek, John A., Wiersch, John, Tschurtschenthaler, Markus, Shiota, Chiyo, Gittes, George K., Billiar, Timothy R., Mollen, Kevin, Kaser, Arthur, Blumberg, Richard, Hackam, David J.

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Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut von Sodhi, Chhinder P, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Good, Misty, Egan, Charlotte, Ozolek, John, Zhu, Xiaorong, Billiar, Timothy R, Hackam, David J

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Dysregulated brain-gut axis in the setting of traumatic brain injury: review of mechanisms and anti-inflammatory pharmacotherapies von El Baassiri, Mahmoud G, Raouf, Zachariah, Badin, Sarah, Escobosa, Alejandro, Sodhi, Chhinder P, Nasr, Isam W

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Xenotransplanted human organoids identify transepithelial zinc transport as a key mediator of intestinal adaptation von Sampah, Maame Efua S., Moore, Hannah, Ahmad, Raheel, Duess, Johannes, Lu, Peng, Lopez, Carla, Steinway, Steve, Scheese, Daniel, Raouf, Zachariah, Tsuboi, Koichi, Ding, Jeffrey, Caputo, Connor, McFarland, Madison, Fulton, William B., Wang, Sanxia, Wang, Meghan, Prindle, Thomas, Gazit, Vered, Rubin, Deborah C., Alaish, Samuel, Sodhi, Chhinder P., Hackam, David J.

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Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis von Yi, Hyun, Patel, Amit K, Sodhi, Chhinder P, Hackam, David J, Hackam, Abigail S

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Animal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges von Lu, Peng, Sodhi, Chhinder P, Jia, Hongpeng, Shaffiey, Shahab, Good, Misty, Branca, Maria F, Hackam, David J

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A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis von Neal, Matthew D, Sodhi, Chhinder P, Dyer, Mitchell, Craig, Brian T, Good, Misty, Jia, Hongpeng, Yazji, Ibrahim, Afrazi, Amin, Richardson, Ward M, Beer-Stolz, Donna, Ma, Congrong, Prindle, Thomas, Grant, Zachary, Branca, Maria F, Ozolek, John, Hackam, David J

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