Chemical Development of CI-1008, an Enantiomerically Pure Anticonvulsant von Hoekstra, Marvin S, Sobieray, Denis M, Schwindt, Mark A, Mulhern, Thomas A, Grote, Todd M, Huckabee, Brian K, Hendrickson, Valerie S, Franklin, Lloyd C, Granger, Eric J, Karrick, Gregory L

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Development of scalable processes to prepare a key chiral, nonracemic intermediate en route to LpxC inhibitors for Gram-negative infections von Sferdean, Calin D., Jaherun, Tuba, Sobieray, Denis M., Vairagoundar, Rajendran, VanderRoest, Ronald J., Westrick, Valerie S., Ghosh, Samir, Mills, Kent A., Millheim, Dominic, Koch, Jason D., Hester, Darryl, Falahatpisheh, Kamran, Walker, Daniel P.

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Unique and Efficient Synthesis of [2S-(2R,3S,4R)]-2-Amino-1-cyclohexyl- 6-methyl-3,4-heptanediol, a Popular C-Terminal Component of Many Renin Inhibitors von Schwindt, Mark A, Belmont, Daniel T, Carlson, Mark, Franklin, Lloyd C, Hendrickson, Valerie S, Karrick, Gregory L, Poe, Russell W, Sobieray, Denis M, Van De Vusse, Jim

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alpha.-Oxoketene dithioacetal chemistry. 2. Conjugate reductions with electrophilic reducing agents von Gammill, Ronald B, Sobieray, Denis M, Gold, Paul M

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“Bicyclobenzodiazepinones” from 3-oxo-1,2-diazetidinium hydroxide, inner salts von Taylor, Edward C., Sobieray, Denis M.

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Chiral HPLC Separations of 1-Azabicyclo[2.2.1]Heptan-3-One and 1-Alkoxycarbonylalkyl-Pyrrolidine-3-Carboxylic Acid Alkyl Ester Enantiomers on Polysaccharide-Based Stationary Phases von Lin, Sechoing, Engelsma, Cara E., Maddox, Nancy J., Huckabee, Brian K., Sobieray, Denis M.

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Method of making (1S, 4R)-1-azabicyclo[2.2.1]heptan-3-one and (1R, 4S), 1-azabicyclo[2.2.1]heptan-3-one von SOBIERAY, DENIS M

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METODO PARA LA PREPARACION DE (1S, 4R)-1-AZABICICLO [2.2.1] HEPTANO-3-ONA Y (1R,4S), 1-AZABICICLO [2.2.1] HEPTANO-3-ONA von SOBIERAY, DENIS M

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METHOD OF OBTAINING (S)-3-(AMINOMETHYL)-5-METHYLOHEXANIC ACID von HUCKABEE BRIAN K, SOBIERAY DENIS M

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METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID von HUCKABEE BRIAN K, SOBIERAY DENIS M

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Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid von HUCKABEE, BRIAN K, SOBIERAY, DENIS M

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Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid von HUCKABEE, BRIAN K, SOBIERAY, DENIS M

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METHOD OF SEPARATING (S)-3-(AMINOMETHYL)-5-METHYLHEXANIC ACID FROM (+)-3-(AMINOMETHYL)-5-METHYLHEXANIC ACID von HUCKABEE BRIAN K, TITUS ROBERT D, SOBIERAY DENIS M, GROTE TODD M, MULHERN THOMAS

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MANDELIC SALT OF 3-(AMINOMETHYL)-5-METHYLHEXANIC ACID von HUCKABEE BRIAN K, TITUS ROBERT D, SOBIERAY DENIS M, GROTE TODD M, MULHERN THOMAS

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METHOD OF OBTAINING (S)-3-(AMINOMETHYL)-5-METHYLHEXANIC ACID von HUCKABEE BRIAN K, TITUS ROBERT D, SOBIERAY DENIS M, GROTE TODD M, MULHERN THOMAS

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METHOD OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID von HUCKABEE BRIAN K, TITUS ROBERT D, SOBIERAY DENIS M, GROTE TODD M, MULHERN THOMAS

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Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid von MULHERN, THOMAS, HUCKABEE, BRIAN K, SOBIERAY, DENIS M, TITUS, ROBERT D, GROTE, TODD M

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GABA and L-glutamic acid analogs for antiseizure treatment von FRANKLIN, LLOYD C, SCHWINDT, MARK A, YUEN, PO-WAI, SOBIERAY, DENIS M, ANDRUSZKIEWICZ, RYSZARD, SILVERMAN, RICHARD B

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GABA and L-glutamic acid analogs for antiseizure treatment von FRANKLIN, LLOYD C, SCHWINDT, MARK A, YUEN, PO-WAI, SOBIERAY, DENIS M, ANDRUSZKIEWICZ, RYSZARD, SILVERMAN, RICHARD B

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