Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)‐Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei... von Cerone, Michela, Uliassi, Elisa, Prati, Federica, Ebiloma, Godwin U., Lemgruber, Leandro, Bergamini, Christian, Watson, David G., de A. M. Ferreira, Thais, Roth Cardoso, Gabriella Simões Heyn, Soares Romeiro, Luiz A., de Koning, Harry P., Bolognesi, Maria Laura

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Front Cover: Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)‐Based Hybrids Target Mitochondrial Function and ATP Production in Trypan... von Cerone, Michela, Uliassi, Elisa, Prati, Federica, Ebiloma, Godwin U., Lemgruber, Leandro, Bergamini, Christian, Watson, David G., de A. M. Ferreira, Thais, Roth Cardoso, Gabriella Simões Heyn, Soares Romeiro, Luiz A., de Koning, Harry P., Bolognesi, Maria Laura

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Use of Adrenergic N-Phenylpiperazine Antagonists, Pahrmaceutical Compositions Containning Them, and Methods of Preparing Them von NOEL FRANCOIS G, PALHARES MIRANDA ANA L, FERREIRA DE BRITO FERNANDA C, SOARES ROMEIRO LUIZ A, CARDOSO DE ALMEIDA HELENA CARLA C, MANSSOUR FRAGA CARLOS A, DE LACERDA BARREIRO ELIEZER DE J, TIBIRICA EDUARDO V, MARTINS DA SILVA CLARDIA L

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Antioxidant activity of eugenol and its acetyl and nitroderivatives: the role of quinone intermediates—a DFT approach of DPPH test von Candido Júnior, José Roberval, Romeiro, Luiz Antonio Soares, Marinho, Emmanuel Silva, Monteiro, Norberto de Kássio Vieira, de Lima-Neto, Pedro

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Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties von de Andrade Ramos, Giselle, Souza de Oliveira, Andressa, Bartolini, Manuela, Naldi, Marina, Liparulo, Irene, Bergamini, Christian, Uliassi, Elisa, Wu, Ling, Fraser, Paul E, Abreu, Monica, Kiametis, Alessandra Sofia, Gargano, Ricardo, Silveira, Edilberto Rocha, Brand, Guilherme D, Prchal, Lukas, Soukup, Ond ej, Korábe ný, Jan, Bolognesi, Maria Laura, Soares Romeiro, Luiz Antonio

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Effect of piplartine and cinnamides on Leishmania amazonensis, Plasmodium falciparum and on peritoneal cells of Swiss mice von Araújo-Vilges, Keline Medeiros de, Oliveira, Stefan Vilges de, Couto, Shirley Claudino Pereira, Fokoue, Harold Hilarion, Romero, Gustavo Adolfo Sierra, Kato, Massuo Jorge, Romeiro, Luiz Antonio Soares, Leite, José Roberto Souza Almeida, Kuckelhaus, Selma Aparecida Souza

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Cashew Nut Shell Liquid (CNSL) as a Source of Drugs for Alzheimer's Disease von Uliassi, Elisa, de Oliveira, Andressa Souza, de Camargo Nascente, Luciana, Romeiro, Luiz Antonio Soares, Bolognesi, Maria Laura

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Effects of cardanol-based phospholipid analogs on Trichomonas vaginalis von de Souza, Tatiana Guinancio, de Lucena Costa, Brenda, Holanda, Cleonice Andrade, Soares Romeiro, Luiz Antonio, de Souza, Wanderley, Benchimol, Marlene

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Engineering a dysbiotic biofilm model for testing root caries interventions through microbial modulation von Dame-Teixeira, Naile, El-Gendy, Reem, de Oliveira, Andressa Souza, Holanda, Cleonice Andrade, Romeiro, Luiz Antonio Soares, Do, Thuy

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Molecular modeling of cardanol-derived AChE inhibitors von de Abreu Silva, Mônica, Sette, Camila D’Avila Braga, Kiametis, Alessandra Sofia, Romeiro, Luiz Antônio Soares, Gargano, Ricardo

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Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease von Lemes, Laís Flávia Nunes, de Andrade Ramos, Giselle, de Oliveira, Andressa Souza, da Silva, Fernanda Motta R., de Castro Couto, Gina, da Silva Boni, Marina, Guimarães, Marcos Jorge R., Souza, Isis Nem O., Bartolini, Manuela, Andrisano, Vincenza, do Nascimento Nogueira, Patrícia Coelho, Silveira, Edilberto Rocha, Brand, Guilherme D., Soukup, Ondřej, Korábečný, Jan, Romeiro, Nelilma C., Castro, Newton G., Bolognesi, Maria Laura, Romeiro, Luiz Antonio Soares

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Sustainable multifunctional phenolic lipids as potential therapeutics in Dentistry von Dame-Teixeira, Naile, El-Gendy, Reem, Monici Silva, Isabela, Holanda, Cleonice Andrade, de Oliveira, Andressa Souza, Romeiro, Luiz Antonio Soares, Do, Thuy

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The α1-adrenoceptor-mediated human hyperplastic prostate cells proliferation is impaired by EGF receptor inhibition von Nascimento-Viana, Jessica Barbosa, Alcántara-Hernández, Rocío, Oliveira-Barros, Eliane, Castello Branco, Luiza A., Feijó, Priscilla R., Soares Romeiro, Luiz Antonio, Nasciutti, Luiz Eurico, Noël, François, García-Sáinz, J. Adolfo, Silva, Claudia Lucia Martins

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Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer’s Disease von Soares Romeiro, Luiz Antonio, da Costa Nunes, Jéssica Larissa, de Oliveira Miranda, Camila, Simões Heyn Roth Cardoso, Gabriella, de Oliveira, Andressa Souza, Gandini, Annachiara, Kobrlova, Tereza, Soukup, Ondrej, Rossi, Michele, Senger, Johanna, Jung, Manfred, Gervasoni, Silvia, Vistoli, Giulio, Petralla, Sabrina, Massenzio, Francesca, Monti, Barbara, Bolognesi, Maria Laura

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Molecular evaluation of anti-inflammatory activity of phenolic lipid extracted from cashew nut shell liquid (CNSL) von de Souza, Marilen Queiroz, Teotônio, Isabella Márcia Soares Nogueira, de Almeida, Fernanda Coutinho, Heyn, Gabriella Simões, Alves, Priscilla Souza, Romeiro, Luiz Antônio Soares, Pratesi, Riccardo, de Medeiros Nóbrega, Yanna Karla, Pratesi, Claudia B

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Combinatory Effect of Pequi Oil ( Caryocar brasiliense )-Based Nanoemulsions Associated to Docetaxel and Anacardic Acid ( Anacardium occidentale ) in Triple-Negative Breast Cancer... von Ombredane, Alicia Simalie, Martins, Natália Ornelas, de Souza, Gabriela Mara Vieira, Araujo, Victor Hugo Sousa, Szlachetka, Ísis O, da Silva, Sebastião William, da Rocha, Márcia Cristina Oliveira, Oliveira, Andressa Souza de, Holanda, Cleonice Andrade, Romeiro, Luiz Antonio Soares, Damas, Elysa Beatriz de Oliveira, Azevedo, Ricardo Bentes, Joanitti, Graziella Anselmo

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Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer’s Disease von Rossi, Michele, Freschi, Michela, de Camargo Nascente, Luciana, Salerno, Alessandra, de Melo Viana Teixeira, Sarah, Nachon, Florian, Chantegreil, Fabien, Soukup, Ondrej, Prchal, Lukáš, Malaguti, Marco, Bergamini, Christian, Bartolini, Manuela, Angeloni, Cristina, Hrelia, Silvana, Soares Romeiro, Luiz Antonio, Bolognesi, Maria Laura

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Novel ultraviolet absorbers derived from cashew nut shell liquid: spectrophotometric, in silico and in vitro assays von De Araújo, Emeli Moura, Romeiro, Luiz Antônio Soares, Rodrigues, Ana Paula, Alves, Priscilla Souza, Silva, Viviane Cândida da, Logrado, Lúcio Paulo Lima, Santos, Maria Lucília dos, Murta, Maria Márcia, Leitão, Álvaro Augusto da Costa, Garcia, Sheila, Dellamora-Ortiz, Gisela Maria

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LDT409 (pan-PPAR partial agonist) mitigates metabolic dysfunction-associated steatotic liver disease in high-fructose-fed mice von Fernandes-da-Silva, Aline, Santana-Oliveira, Daiana Araujo, Oliveira, Andressa S de, Ferreira, Thaís A.M., Monteiro, Natália Cipriano, Silva-Veiga, Flávia Maria, Martins, Fabiane Ferreira, Cummins, Carolyn L., Romeiro, Luiz Antonio Soares, Souza-Mello, Vanessa

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Novel ultraviolet absorbers derived from cashew nut shell liquid: spectrophotometric, in silico and in vitro assays von Emeli Moura de Araújo, Luiz Antônio Soares Romeiro, Ana Paula Rodrigues, Priscilla Souza Alves, Viviane Cândida da Silva, Lúcio Paulo Lima Logrado, Maria Lucília dos Santos, Maria Márcia Murta, Álvaro Augusto da Costa Leitão, Sheila Garcia, Gisela Maria Dellamora-Ortiz

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