Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design von Malone, Brandon, Urakova, Nadya, Snijder, Eric J., Campbell, Elizabeth A.

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A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis von Snijder, Eric J, Limpens, Ronald W A L, de Wilde, Adriaan H, de Jong, Anja W M, Zevenhoven-Dobbe, Jessika C, Maier, Helena J, Faas, Frank F G A, Koster, Abraham J, Bárcena, Montserrat

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Arterivirus molecular biology and pathogenesis von Snijder, Eric J, Kikkert, Marjolein, Fang, Ying

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Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements von Manfredonia, Ilaria, Nithin, Chandran, Ponce-Salvatierra, Almudena, Ghosh, Pritha, Wirecki, Tomasz K, Marinus, Tycho, Ogando, Natacha S, Snijder, Eric J, van Hemert, Martijn J, Bujnicki, Janusz M, Incarnato, Danny

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In vitro reconstitution of SARS-coronavirus mRNA cap methylation von Bouvet, Mickaël, Debarnot, Claire, Imbert, Isabelle, Selisko, Barbara, Snijder, Eric J, Canard, Bruno, Decroly, Etienne

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Double-Membrane Vesicles as Platforms for Viral Replication von Wolff, Georg, Melia, Charlotte E., Snijder, Eric J., Bárcena, Montserrat

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One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities von Subissi, Lorenzo, Posthuma, Clara C, Collet, Axelle, Zevenhoven-Dobbe, Jessika C, Gorbalenya, Alexander E, Decroly, Etienne, Snijder, Eric J, Canard, Bruno, Imbert, Isabelle

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The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2 von Ogando, Natacha S, Zevenhoven-Dobbe, Jessika C, van der Meer, Yvonne, Bredenbeek, Peter J, Posthuma, Clara C, Snijder, Eric J

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The PRRSV replicase: Exploring the multifunctionality of an intriguing set of nonstructural proteins von Fang, Ying, Snijder, Eric J.

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α‑Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment von Zhang, Linlin, Lin, Daizong, Kusov, Yuri, Nian, Yong, Ma, Qingjun, Wang, Jiang, von Brunn, Albrecht, Leyssen, Pieter, Lanko, Kristina, Neyts, Johan, de Wilde, Adriaan, Snijder, Eric J, Liu, Hong, Hilgenfeld, Rolf

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A molecular pore spans the double membrane of the coronavirus replication organelle von Wolff, Georg, Limpens, Ronald W. A. L., Zevenhoven-Dobbe, Jessika C., Laugks, Ulrike, Zheng, Shawn, de Jong, Anja W. M., Koning, Roman I., Agard, David A., Grünewald, Kay, Koster, Abraham J., Snijder, Eric J., Bárcena, Montserrat

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SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology von Ogando, Natacha S, Dalebout, Tim J, Zevenhoven-Dobbe, Jessika C, Limpens, Ronald W A L, van der Meer, Yvonne, Caly, Leon, Druce, Julian, de Vries, Jutte J C, Kikkert, Marjolein, Bárcena, Montserrat, Sidorov, Igor, Snijder, Eric J

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The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity von Ogando, Natacha S, Ferron, Francois, Decroly, Etienne, Canard, Bruno, Posthuma, Clara C, Snijder, Eric J

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Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture von DE WILDE, Adriaan H, JOCHMANS, Dirk, POSTHUMA, Clara C, ZEVENHOVEN-DOBBE, Jessika C, VAN NIEUWKOOP, Stefan, BESTEBROER, Theo M, VAN DEN HOOGEN, Bernadette G, NEYTS, Johan, SNIJDER, Eric J

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Discovery of the first insect nidovirus, a missing evolutionary link in the emergence of the largest RNA virus genomes von Nga, Phan Thi, Parquet, Maria del Carmen, Lauber, Chris, Parida, Manmohan, Nabeshima, Takeshi, Yu, Fuxun, Thuy, Nguyen Thanh, Inoue, Shingo, Ito, Takashi, Okamoto, Kenta, Ichinose, Akitoyo, Snijder, Eric J, Morita, Kouichi, Gorbalenya, Alexander E

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A swine arterivirus deubiquitinase stabilizes two major envelope proteins and promotes production of viral progeny von Guo, Rui, Yan, Xingyu, Li, Yanhua, Cui, Jin, Misra, Saurav, Firth, Andrew E, Snijder, Eric J, Fang, Ying

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Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronav... von Oudshoorn, Diede, Rijs, Kevin, Limpens, Ronald W A L, Groen, Kevin, Koster, Abraham J, Snijder, Eric J, Kikkert, Marjolein, Bárcena, Montserrat

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Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity von Schoggins, John W., MacDuff, Donna A., Imanaka, Naoko, Gainey, Maria D., Shrestha, Bimmi, Eitson, Jennifer L., Mar, Katrina B., Richardson, R. Blake, Ratushny, Alexander V., Litvak, Vladimir, Dabelic, Rea, Manicassamy, Balaji, Aitchison, John D., Aderem, Alan, Elliott, Richard M., García-Sastre, Adolfo, Racaniello, Vincent, Snijder, Eric J., Yokoyama, Wayne M., Diamond, Michael S., Virgin, Herbert W., Rice, Charles M.

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SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum von Knoops, Kèvin, Kikkert, Marjolein, Worm, Sjoerd H E van den, Zevenhoven-Dobbe, Jessika C, van der Meer, Yvonne, Koster, Abraham J, Mommaas, A Mieke, Snijder, Eric J

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Mechanism of nucleic acid unwinding by SARS-CoV helicase von Adedeji, Adeyemi O, Marchand, Bruno, Te Velthuis, Aartjan J W, Snijder, Eric J, Weiss, Susan, Eoff, Robert L, Singh, Kamalendra, Sarafianos, Stefan G

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