Modeling the ACMG/AMP variant classification guidelines as a Bayesian classification framework von Tavtigian, Sean V, Greenblatt, Marc S, Harrison, Steven M, Nussbaum, Robert L, Prabhu, Snehit A, Boucher, Kenneth M, Biesecker, Leslie G

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Ultrafast genome-wide scan for SNP-SNP interactions in common complex disease von Prabhu, Snehit, Pe'er, Itsik

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Overlapping pools for high-throughput targeted resequencing von Prabhu, Snehit, Pe'er, Itsik

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Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling von Weber, Evan W, Parker, Kevin R, Sotillo, Elena, Lynn, Rachel C, Anbunathan, Hima, Lattin, John, Good, Zinaida, Belk, Julia A, Daniel, Bence, Klysz, Dorota, Malipatlolla, Meena, Xu, Peng, Bashti, Malek, Heitzeneder, Sabine, Labanieh, Louai, Vandris, Panayiotis, Majzner, Robbie G, Qi, Yanyan, Sandor, Katalin, Chen, Ling-Chun, Prabhu, Snehit, Gentles, Andrew J, Wandless, Thomas J, Satpathy, Ansuman T, Chang, Howard Y, Mackall, Crystal L

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Caenorhabditis elegans mutant allele identification by whole-genome sequencing von Sarin, Sumeet, O'Meara, M Maggie, Hobert, Oliver, Pe'er, Itsik, Prabhu, Snehit

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Disease Burden Affects Outcomes in Pediatric and Young Adult B-Cell Lymphoblastic Leukemia After Commercial Tisagenlecleucel: A Pediatric Real-World Chimeric Antigen Receptor Conso... von Schultz, Liora M, Baggott, Christina, Prabhu, Snehit, Pacenta, Holly L, Phillips, Christine L, Rossoff, Jenna, Stefanski, Heather E, Talano, Julie-An, Moskop, Amy, Margossian, Steven P, Verneris, Michael R, Myers, Gary Douglas, Karras, Nicole A, Brown, Patrick A, Qayed, Muna, Hermiston, Michelle, Satwani, Prakash, Krupski, Christa, Keating, Amy K, Wilcox, Rachel, Rabik, Cara A, Fabrizio, Vanessa A, Rouce, Rayne H, Chinnabhandar, Vasant, Kunicki, Michael, Barsan, Valentin V, Goksenin, A Yasemin, Li, Yimei, Mavroukakis, Sharon, Egeler, Emily, Curran, Kevin J, Mackall, Crystal L, Laetsch, Theodore W

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Post-infusion CAR TReg cells identify patients resistant to CD19-CAR therapy von Good, Zinaida, Spiegel, Jay Y., Sahaf, Bita, Malipatlolla, Meena B., Ehlinger, Zach J., Kurra, Sreevidya, Desai, Moksha H., Reynolds, Warren D., Wong Lin, Anita, Vandris, Panayiotis, Wu, Fang, Prabhu, Snehit, Hamilton, Mark P., Tamaresis, John S., Hanson, Paul J., Patel, Shabnum, Feldman, Steven A., Frank, Matthew J., Baird, John H., Muffly, Lori, Claire, Gursharan K., Craig, Juliana, Kong, Katherine A., Wagh, Dhananjay, Coller, John, Bendall, Sean C., Tibshirani, Robert J., Plevritis, Sylvia K., Miklos, David B., Mackall, Crystal L.

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Outcomes After Nonresponse and Relapse Post-Tisagenlecleucel in Children, Adolescents, and Young Adults With B-Cell Acute Lymphoblastic Leukemia von Schultz, Liora M, Eaton, Anne, Baggott, Christina, Rossoff, Jenna, Prabhu, Snehit, Keating, Amy K, Krupski, Christa, Pacenta, Holly, Philips, Christine L, Talano, Julie-An, Moskop, Amy, Baumeister, Susanne H C, Myers, Gary Douglas, Karras, Nicole A, Brown, Patrick A, Qayed, Muna, Hermiston, Michelle, Satwani, Prakash, Wilcox, Rachel, Rabik, Cara A, Fabrizio, Vanessa A, Chinnabhandar, Vasant, Kunicki, Michael, Mavroukakis, Sharon, Egeler, Emily, Li, Yimei, Mackall, Crystal L, Curran, Kevin J, Verneris, Michael R, Laetsch, Theodore W, Stefanski, Heather

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Transcriptional Profiling Associated with CD22 CAR T Cell Clinical Response in LBCL von Kramer, Anne Marijn, Hamilton, Mark P., Prabhu, Snehit, Desai, Moksha, Kuo, Adam, Ehlinger, Zachary, Agarwal, Neha, Su, Yi-Jiun, Gkitsas, Nikolaos, Fowler, Carley, Keerthi, Vimal, Retherford, Aidan, Klysz, Dorota, Tunuguntla, Ramya, Feldman, Steven, Sahaf, Bita, Baird, John H., Muffly, Lori S., Mackall, Crystal L., Miklos, David B., Good, Zinaida, Frank, Matthew J.

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Establishing Costs for Commercial Chimeric Antigen Receptor T-Cell (Tisagenlecleucel; Kymriah) in Children and Young Adult B-Cell Acute Lymphoblastic Leukemia; A Merged Analysis fr... von Satwani, Prakash, Chao, Karen, Lopez-Garcia, Maria, Hall, Matt, Jin, Zhezhen, Winestone, Lena E, Friedman, Danielle Novetsky, Phelan, Rachel, Baggott, Christina, John, Samuel, Pacenta, Holly L., Laetsch, Theodore W., Phillips, Christine L, Verneris, Michael R, Fabrizio, Vanessa A., Keating, Amy, Talano, Julie-An, Moskop, Amy, Baumeister, Susanne H.C., Qayed, Muna, Myers, Doug Douglas, Hall, Erin Marie, Prabhu, Snehit, Nguyen, Khanh, Carr, Casey A, Mackall, Crystal L., Lin, John K, Goldhaber-Fiebert, Jeremy, Schultz, Liora Michal

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Risk Factors and Outcomes for Hematotoxicity Following Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia von McNerney, Kevin O., Fabrizio, Vanessa A., Talleur, Aimee C., Si Lim, Stephanie, Dreyzin, Alexandra, Baggott, Christina, Vatsayan, Anant, Rossoff, Jenna, Prabhu, Snehit, Pacenta, Holly L., Phillips, Christine L, Talano, Julie-An, Moskop, Amy, Verneris, Michael R, Myers, Douglas, Karras, Nicole, Bonifant, Challice L., Qayed, Muna, Hermiston, Michelle L., Satwani, Prakash, Krupski, Christa, Keating, Amy, Baumeister, Susanne H.C., Chinnabhandar, Vasant, Egeler, Emily, Curran, Kevin J, Mackall, Crystal L., Laetsch, Theodore W., Schultz, Liora Michal, Naik, Swati

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Peripheral Blast Count at Apheresis Acts Independent of Disease Burden As a Risk Factor for Survival Following Tisagenlecleucel in Children and Young Adults von Fabrizio, Vanessa A., Miller, Kristen, Baggott, Christina, Prabhu, Snehit, Pacenta, Holly, Phillips, Christine L., Rossoff, Jenna, Stefanski, Heather E., Talano, Julie, Moskop, Amy, Baumeister, Susanne H.C., Myers, Gary Douglas, Karras, Nicole, Brown, Patrick A., Qayed, Muna, Hermiston, Michelle L., Satwani, Prakash, Krupski, Christa, Wilcox, Rachel, Chinnabhandar, Vasant, Curran, Kevin J., Mackall, Crystal L., Laetsch, Theodore W., Keating, Amy K., Verneris, Michael R., Schultz, Liora M.

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IMMU-60. MYELOID POPULATIONS MODULATE GD2 CAR T CELL ACTIVITY IN DIFFUSE MIDLINE GLIOMA von Ramakrishna, Sneha, Geraghty, Anna, Good, Zinaida, Desai, Moksha, Mancusi, Rebecca, Mahdi, Jasia, Song, Kun Wei, Ehlinger, Zachary, Chen, Yiyun, Hamilton, Mark, Rietberg, Skyler, Majzner, Robbie, Schultz, Liora, Richards, Becky, Kamens, Jennifer, Barsan, Vali, Campen, Cynthia, Partap, Sonia, Moon, Jennifer, Baggott, Christina, Kunick, Michael, Fujimoto, Michelle, Li, Amy, Jariwala, Sneha, Mavroukakis, Sharon, Egeler, Emily, Jacobs, Ashley, Erickson, Courtney, Prabhu, Snehit, Davis, Kara, Feldman, Steven, Sahaf, Bita, Mackall, Crystal, Monje, Michelle

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Intravenous and intracranial GD2-CAR T cells for H3K27M + diffuse midline gliomas von Monje, Michelle, Mahdi, Jasia, Majzner, Robbie, Yeom, Kristen W, Schultz, Liora M, Richards, Rebecca M, Barsan, Valentin, Song, Kun-Wei, Kamens, Jen, Baggott, Christina, Kunicki, Michael, Rietberg, Skyler P, Lim, Alexandria Sung, Reschke, Agnes, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Patel, Shabnum, Chinnasamy, Harshini, Erickson, Courtney, Jacobs, Ashley, Duh, Allison K, Tunuguntla, Ramya, Klysz, Dorota Danuta, Fowler, Carley, Green, Sean, Beebe, Barbara, Carr, Casey, Fujimoto, Michelle, Brown, Annie Kathleen, Petersen, Ann-Louise G, McIntyre, Catherine, Siddiqui, Aman, Lepori-Bui, Nadia, Villar, Katlin, Pham, Kymhuynh, Bove, Rachel, Musa, Eric, Reynolds, Warren D, Kuo, Adam, Prabhu, Snehit, Rasmussen, Lindsey, Cornell, Timothy T, Partap, Sonia, Fisher, Paul G, Campen, Cynthia J, Grant, Gerald, Prolo, Laura, Ye, Xiaobu, Sahaf, Bita, Davis, Kara L, Feldman, Steven A, Ramakrishna, Sneha, Mackall, Crystal

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Author Correction: Intravenous and intracranial GD2-CAR T cells for H3K27M+ diffuse midline gliomas von Monje, Michelle, Mahdi, Jasia, Majzner, Robbie, Yeom, Kristen W., Schultz, Liora M., Richards, Rebecca M., Barsan, Valentin, Song, Kun-Wei, Kamens, Jen, Baggott, Christina, Kunicki, Michael, Rietberg, Skyler P., Lim, Alexandria Sung, Reschke, Agnes, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Patel, Shabnum, Chinnasamy, Harshini, Erickson, Courtney, Jacobs, Ashley, Duh, Allison K., Tunuguntla, Ramya, Klysz, Dorota Danuta, Fowler, Carley, Green, Sean, Beebe, Barbara, Carr, Casey, Fujimoto, Michelle, Brown, Annie Kathleen, Petersen, Ann-Louise G., McIntyre, Catherine, Siddiqui, Aman, Lepori-Bui, Nadia, Villar, Katlin, Pham, Kymhuynh, Bove, Rachel, Musa, Eric, Reynolds, Warren D., Kuo, Adam, Prabhu, Snehit, Rasmussen, Lindsey, Cornell, Timothy T., Partap, Sonia, Fisher, Paul G., Campen, Cynthia J., Grant, Gerald, Prolo, Laura, Ye, Xiaobu, Sahaf, Bita, Davis, Kara L., Feldman, Steven A., Ramakrishna, Sneha, Mackall, Crystal

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Obesity Associates with Inferior Outcomes and Toxicity in Pediatric and Young Adult Patient with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Treated with Commercially M... von Ross, Anthony J, Baggott, Christina, Prabhu, Snehit, Pacenta, Holly, Philips, Christine, Rossoff, Jenna, Stefanski, Heather E, Talano, Julie, Moskop, Amy, Baumeister, Susanne H.C., Verneris, Michael R, Myers, Gary Douglas, Karras, Nicole, Qayed, Muna, Hermiston, Michelle L., Satwani, Prakash, Krupski, Christa, Keating, Amy K., Wilcox, Rachel, Fabrizio, Vanessa A, Chinnabhandar, Vasant, Curran, Kevin J., Mackall, Crystal L., Laetsch, Theodore W., Althouse, Sandra K, Maude, Shannon L., Henry, Curtis J, Schultz, Liora M., Skiles, Jodi L.

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Out-of-specification tisagenlecleucel does not compromise safety or efficacy in pediatric acute lymphoblastic leukemia von Rossoff, Jenna, Baggott, Christina, Prabhu, Snehit, Pacenta, Holly, Phillips, Christine L., Stefanski, Heather, Talano, Julie-An, Moskop, Amy, Margossian, Steven P., Verneris, Michael R., Myers, Gary Douglas, Karras, Nicole, Brown, Patrick A., Qayed, Muna, Hermiston, Michelle, Satwani, Prakash, Krupski, Christa, Keating, Amy K., Wilcox, Rachel, Rabik, Cara A., Fabrizio, Vanessa A., Kunicki, Michael, Chinnabhandar, Vasant, Goksenin, A. Yasemin, Curran, Kevin J., Mackall, Crystal L., Laetsch, Theodore W., Schultz, Liora M.

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Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy von Fabrizio, Vanessa A., Boelens, Jaap Jan, Mauguen, Audrey, Baggott, Christina, Prabhu, Snehit, Egeler, Emily, Mavroukakis, Sharon, Pacenta, Holly, Phillips, Christine L., Rossoff, Jenna, Stefanski, Heather E., Talano, Julie-An, Moskop, Amy, Margossian, Steven P., Verneris, Michael R., Myers, Gary Douglas, Karras, Nicole A., Brown, Patrick A., Qayed, Muna, Hermiston, Michelle, Satwani, Prakash, Krupski, Christa, Keating, Amy K., Wilcox, Rachel, Rabik, Cara A., Chinnabhandar, Vasant, Kunicki, Michael, Goksenin, A. Yasemin, Mackall, Crystal L., Laetsch, Theodore W., Schultz, Liora M., Curran, Kevin J.

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Transient “rest” restores functionality in exhausted CAR-T cells via epigenetic remodeling von Weber, Evan W., Parker, Kevin R., Sotillo, Elena, Lynn, Rachel C., Anbunathan, Hima, Lattin, John, Good, Zinaida, Belk, Julia A., Daniel, Bence, Klysz, Dorota, Malipatlolla, Meena, Xu, Peng, Bashti, Malek, Heitzeneder, Sabine, Labanieh, Louai, Vandris, Panayiotis, Majzner, Robbie G., Qi, Yanyan, Sandor, Katalin, Chen, Ling-Chun, Prabhu, Snehit, Gentles, Andrew J., Wandless, Thomas J., Satpathy, Ansuman T., Chang, Howard Y., Mackall, Crystal L.

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DIPG-47. SEQUENTIAL INTRAVENOUS AND INTRACEREBROVENTRICULAR GD2-CAR T-CELL THERAPY FOR H3K27M-MUTATED DIFFUSE MIDLINE GLIOMAS von Monje, Michelle, Mahdi, Jasia, Majzner, Robbie G, Yeom, Kristen, Schultz, Liora M, Richards, Rebecca, Barsan, Valentin, Song, Kun-Wei, Kamens, Jennifer, Baggott, Christina, Kunicki, Michael, Lim, Alexandria Sung, Reschke, Agnes, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Patel, Shabnum, Chinnasamy, Harshini, Erickson, Courtney, Jacobs, Ashley, Duh, Allison K, Rietberg, Skyler P, Tunuguntla, Ramya, Klysz, Dorota Danuta, Fowler, Carley, Green, Sean, Beebe, Barbara, Carr, Casey, Fujimoto, Michelle, Brown, Annie Kathleen, Peterson, Ann-Louise G, McIntyre, Catherine, Siddiqui, Aman, Lepori-Bui, Nadia, Villar, Katlin, Pham, Kymhuynh, Bove, Rachel, Musa, Eric, Reynolds, Warren, Kuo, Adam, Prabhu, Snehit, Rasmussen, Lindsey, Cornell, Timothy T, Partap, Soni, Fisher, Paul G, Campen, Cynthia J, Grant, Gerald, Prolo, Laura, Ye, Xiaobu, Sahaf, Bita, Davis, Kara L, Feldman, Steven A, Ramakrishna, Sneha, Mackall, Crystal L

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