Pharmacogenetics of irinotecan metabolism and transport: An update von Smith, Nicola F., Figg, William D., Sparreboom, Alex

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Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel von Smith, Nicola F, Acharya, Milin R, Desai, Neil, Figg, William D, Sparreboom, Alex

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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity von Stimson, Lindsay, Rowlands, Martin G, Newbatt, Yvette M, Smith, Nicola F, Raynaud, Florence I, Rogers, Paul, Bavetsias, Vassilios, Gorsuch, Stephen, Jarman, Michael, Bannister, Andrew, Kouzarides, Tony, McDonald, Edward, Workman, Paul, Aherne, G Wynne

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The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery von Smith, Nicola F, Raynaud, Florence I, Workman, Paul

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Role of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination von Smith, Nicola F, Figg, William D, Sparreboom, Alex

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LC–MS/MS quantification of a neuropeptide fragment kisspeptin-10 (NSC 741805) and characterization of its decomposition product and pharmacokinetics in rats von Liu, Zhongfa, Ren, Chen, Jones, William, Chen, Ping, Seminara, Stephanie B., Chan, Yee-Ming, Smith, Nicola F., Covey, Joseph M., Wang, Jeffrey, Chan, Kenneth K.

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Effect of Common CYP3A4 and CYP3A5 Variants on the Pharmacokinetics of the Cytochrome P450 3A Phenotyping Probe Midazolam in Cancer Patients von LEPPER, Erin R, BAKER, Sharyn D, INGERSOLL, Roxann G, BATES, Susan E, MATHIJSSEN, Ron H. J, VERWEIJ, Jaap, FIGG, William D, SPARREBOOM, Alex, PERMENTER, Matt, RIES, Nicole, VAN SCHAIK, Ron H. N, SCHENK, Paul W, PRICE, Douglas K, AHN, Danielle, SMITH, Nicola F, CUSATIS, George

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Influence of the dual ABCB1 and ABCG2 inhibitor tariquidar on the disposition of oral imatinib in mice von Gardner, Erin R, Smith, Nicola F, Figg, William D, Sparreboom, Alex

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Preclinical pharmacokinetics and metabolism of a novel diaryl pyrazole resorcinol series of heat shock protein 90 inhibitors von Smith, Nicola F, Hayes, Angela, James, Karen, Nutley, Bernard P, McDonald, Edward, Henley, Alan, Dymock, Brian, Drysdale, Martin J, Raynaud, Florence I, Workman, Paul

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Liquid chromatography–mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma von Parise, Robert A., Beumer, Jan H., Kangani, Cyrous O., Holleran, Julianne L., Eiseman, Julie L., Smith, Nicola F., Covey, Joseph M., Perrine, Susan P., Egorin, Merrill J.

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In vitro and In vivo Clinical Pharmacology of Dimethyl Benzoylphenylurea, a Novel Oral Tubulin-Interactive Agent von Rudek, Michelle A, Zhao, Ming, Smith, Nicola F, Robey, Robert W, He, Ping, Hallur, Gurulingappa, Khan, Saeed, Hidalgo, Manuel, Jimeno, Antonio, Colevas, A Dimitrios, Messersmith, Wells A, Wolff, Antonio C, Baker, Sharyn D

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Induction of CYP3A4 by Vinblastine: Role of the Nuclear Receptor NR1I2 von Smith, Nicola F, Mani, Sridhar, Schuetz, Erin G, Yasuda, Kazuto, Sissung, Tristan M, Bates, Susan E, Figg, William D, Sparreboom, Alex

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Recent advances in pharmacogenetic approaches to anticancer drug development von Smith, Nicola F., Figg, William D., Sparreboom, Alex

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Induction of CYP3A4 by Vinblastine: Role of the Nuclear Receptor NR112 von SMITH, Nicola F, MANI, Sridhar, SCHUETZ, Erin G, YASUDA, Kazuto, SISSUNG, Tristan M, BATES, Susan E, FIGG, William D, SPARREBOOM, Alex

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Recent advances in pharmacogenetic approaches to anticancer drug development: Applying pharmacogenomics in drug development: part II von SMITH, Nicola F, FIGG, William D, SPARREBOOM, Alex

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In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-lnteractive agent von RUDEK, Michelle A, MING ZHAO, MESSERSMITH, Wells A, WOLFF, Antonio C, BAKER, Sharyn D, SMITH, Nicola F, ROBEY, Robert W, PING HE, HALLUR, Gurulingappa, KHAN, Saeed, HIDALGO, Manuel, JIMENO, Antonio, COLEVAS, A. Dimitrios

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Effect of Common CYP3A4 and CYP3A5 Variants on the Pharmacokinetics of the Cytochrome P 450 3A Phenotyping Probe Midazolam in Cancer Patients von Lepper, Erin R., Baker, Sharyn D., Permenter, Matt, Ries, Nicole, van Schaik, Ron H.N., Schenk, Paul W., Price, Douglas K., Ahn, Danielle, Smith, Nicola F., Cusatis, George, Ingersoll, Roxann G., Bates, Susan E., Mathijssen, Ron H.J., Verweij, Jaap, Figg, William D., Sparreboom, Alex

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Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel von Smith, Nicola F., Acharya, Milin R., Desai, Neil, Figg, II, William, Sparreboom, Alex

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The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions von Littlejohns, Thomas J., Holliday, Jo, Gibson, Lorna M., Garratt, Steve, Oesingmann, Niels, Alfaro-Almagro, Fidel, Bell, Jimmy D., Boultwood, Chris, Collins, Rory, Conroy, Megan C., Crabtree, Nicola, Doherty, Nicola, Frangi, Alejandro F., Harvey, Nicholas C., Leeson, Paul, Miller, Karla L., Neubauer, Stefan, Petersen, Steffen E., Sellors, Jonathan, Sheard, Simon, Smith, Stephen M., Sudlow, Cathie L. M., Matthews, Paul M., Allen, Naomi E.

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Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution von Koel, Björn F., Burke, David F., Bestebroer, Theo M., van der Vliet, Stefan, Zondag, Gerben C. M., Vervaet, Gaby, Skepner, Eugene, Lewis, Nicola S., Spronken, Monique I. J., Russell, Colin A., Eropkin, Mikhail Y., Hurt, Aeron C., Barr, Ian G., de Jong, Jan C., Rimmelzwaan, Guus F., Osterhaus, Albert D. M. E., Fouchier, Ron A. M., Smith, Derek J.

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