Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression von McCabe, Amanda, Smith, Julianne N P, Costello, Angelica, Maloney, Jackson, Katikaneni, Divya, MacNamara, Katherine C

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A novel porous mechanical framework for modelling the interaction between coronary perfusion and myocardial mechanics von Cookson, A.N, Lee, J, Michler, C, Chabiniok, R, Hyde, E, Nordsletten, D.A, Sinclair, M, Siebes, M, Smith, N.P

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A Quantitative Analysis of Cardiac Myocyte Relaxation: A Simulation Study von Niederer, S.A., Hunter, P.J., Smith, N.P.

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Biophysical Modeling to Simulate the Response to Multisite Left Ventricular Stimulation Using a Quadripolar Pacing Lead von NIEDERER, STEVEN A., SHETTY, A.K., PLANK, G., BOSTOCK, J., RAZAVI, R., SMITH, N.P., RINALDI, C.A.

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Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia von Smith, Julianne N P, Kanwar, Vikramjit S, MacNamara, Katherine C

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Aged marrow macrophages expand platelet-biased hematopoietic stem cells via interleukin-1B von Frisch, Benjamin J., Hoffman, Corey M., Latchney, Sarah E., LaMere, Mark W., Myers, Jason, Ashton, John, Li, Allison J., Saunders, Jerry, Palis, James, Perkins, Archibald S., McCabe, Amanda, Smith, Julianne N.P., McGrath, Kathleen E., Rivera-Escalera, Fatima, McDavid, Andrew, Liesveld, Jane L., Korshunov, Vyacheslav A., Elliott, Michael R., MacNamara, Katherine C., Becker, Michael W., Calvi, Laura M.

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A novel methodology for personalized simulations of ventricular hemodynamics from noninvasive imaging data von de Vecchi, A, Gomez, A, Pushparajah, K, Schaeffter, T, Simpson, J.M, Razavi, R, Penney, G.P, Smith, N.P, Nordsletten, D.A

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Type I interferons drive hematopoietic progenitor cell depletion via necroptosis in a model of severe rickettsial infection von Smith, Julianne N.P, McCabe, Amanda, MacNamara, Katherine

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A Biophysically Based Mathematical Model of Unitary Potential Activity in Interstitial Cells of Cajal von Faville, R.A., Pullan, A.J., Sanders, K.M, Smith, N.P.

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15-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration von Smith, Julianne N. P., Dawson, Dawn M., Christo, Kelsey F., Jogasuria, Alvin P., Cameron, Mark J., Antczak, Monika, Ready, Joseph M., Gerson, Stanton L., Markowitz, Sanford D., Desai, Amar B.

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2234P Local immune-related adverse events (irAEs) are more common in tumor-bearing organs von Blum, S.M., Ouyang, B., Zubiri, L., Leonard, D., Barth, J., Zlotoff, D.A., Smith, N.P., Lawrence, D.P., Juric, D., Stone, J.R., Dougan, M., Villani, A-C., Reynolds, K.L., Mino-Kenudson, M., Sullivan, R.J.

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Coupling multi-physics models to cardiac mechanics von Nordsletten, D.A., Niederer, S.A., Nash, M.P., Hunter, P.J., Smith, N.P.

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Simulating left ventricular fluid–solid mechanics through the cardiac cycle under LVAD support von McCormick, M., Nordsletten, D.A., Kay, D., Smith, N.P.

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Investigating a Novel Activation-Repolarisation Time Metric to Predict Localised Vulnerability to Reentry Using Computational Modelling von Hill, Yolanda R, Child, Nick, Hanson, Ben, Wallman, Mikael, Coronel, Ruben, Plank, Gernot, Rinaldi, Christopher A, Gill, Jaswinder, Smith, Nicolas P, Taggart, Peter, Bishop, Martin J

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A spatially-distributed computational model to quantify behaviour of contrast agents in MR perfusion imaging von Cookson, A.N., Lee, J., Michler, C., Chabiniok, R., Hyde, E., Nordsletten, D., Smith, N.P.

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CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia von Seyfried, Allison N., McCabe, Amanda, Smith, Julianne N. P., Calvi, Laura M., MacNamara, Katherine C.

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15-PGDH Inhibition Mitigates Aplastic Anemia Severity von Smith, Julianne N.P., Otegbeye, Folashade, Jogasuria, Alvin, Markowitz, Sanford, Desai, Amar

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Type I IFNs drive hematopoietic stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like ehrlichial infection von Smith, Julianne N P, Zhang, Yubin, Li, Jing Jing, McCabe, Amanda, Jo, Hui Jin, Maloney, Jackson, MacNamara, Katherine C

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Concise Review: Current Concepts in Bone Marrow Microenvironmental Regulation of Hematopoietic Stem and Progenitor Cells von Smith, Julianne N. P., Calvi, Laura M.

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Towards a fast and efficient approach for modelling the patient-specific ventricular haemodynamics von de Vecchi, A., Gomez, A., Pushparajah, K., Schaeffter, T., Nordsletten, D.A., Simpson, J.M., Penney, G.P., Smith, N.P.

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