Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides von Smith, Mark E. B, Schumacher, Felix F, Ryan, Chris P, Tedaldi, Lauren M, Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R

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Regioselective and Stoichiometrically Controlled Conjugation of Photodynamic Sensitizers to a HER2 Targeting Antibody Fragment von Bryden, Francesca, Maruani, Antoine, Savoie, Huguette, Chudasama, Vijay, Smith, Mark E. B, Caddick, Stephen, Boyle, Ross W

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Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation von Castañeda, Lourdes, Maruani, Antoine, Schumacher, Felix F, Miranda, Enrique, Chudasama, Vijay, Chester, Kerry A, Baker, James R, Smith, Mark E B, Caddick, Stephen

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Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody-drug conjugate (ADC) von Nunes, João P M, Morais, Maurício, Vassileva, Vessela, Robinson, Eifion, Rajkumar, Vineeth S, Smith, Mark E B, Pedley, R Barbara, Caddick, Stephen, Baker, James R, Chudasama, Vijay

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Substrate spectrum of ω-transaminase from Chromobacterium violaceum DSM30191 and its potential for biocatalysis von Kaulmann, Ursula, Smithies, Kirsty, Smith, Mark E.B., Hailes, Helen C., Ward, John M.

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Homogeneous Bispecifics by Disulfide Bridging von Hull, Elizabeth A, Livanos, Maria, Miranda, Enrique, Smith, Mark E. B, Chester, Kerry A, Baker, James R

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Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis von Morais, Maurício, Nunes, João P M, Karu, Kersti, Forte, Nafsika, Benni, Irene, Smith, Mark E B, Caddick, Stephen, Chudasama, Vijay, Baker, James R

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Directed evolution to re-adapt a co-evolved network within an enzyme von Strafford, John, Payongsri, Panwajee, Hibbert, Edward G., Morris, Phattaraporn, Batth, Sukhjeet S., Steadman, David, Smith, Mark E.B., Ward, John M., Hailes, Helen C., Dalby, Paul A.

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Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis von Ryan, Chris P, Smith, Mark E B, Schumacher, Felix F, Grohmann, Dina, Papaioannou, Danai, Waksman, Gabriel, Werner, Finn, Baker, James R, Caddick, Stephen

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Bromopyridazinedione-mediated protein and peptide bioconjugation von Chudasama, Vijay, Smith, Mark E. B., Schumacher, Felix F., Papaioannou, Danai, Waksman, Gabriel, Baker, James R., Caddick, Stephen

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Pyridazinediones deliver potent, stable, targeted and efficacious antibody–drug conjugates (ADCs) with a controlled loading of 4 drugs per antibody von Robinson, Eifion, Nunes, João P. M., Vassileva, Vessela, Maruani, Antoine, Nogueira, João C. F., Smith, Mark E. B., Pedley, R. Barbara, Caddick, Stephen, Baker, James R., Chudasama, Vijay

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A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation von Morgan, Rachel E, Chudasama, Vijay, Moody, Paul, Smith, Mark E B, Caddick, Stephen

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A platform for efficient, thiol-stable conjugation to albumin's native single accessible cysteine von Smith, Mark E B, Caspersen, Mikael B, Robinson, Eifion, Morais, Maurício, Maruani, Antoine, Nunes, João P M, Nicholls, Karl, Saxton, Malcolm J, Caddick, Stephen, Baker, James R, Chudasama, Vijay

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Correction: Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis von Morais, Maurício, Nunes, João P. M, Karu, Kersti, Forte, Nafsika, Benni, Irene, Smith, Mark E. B, Caddick, Stephen, Chudasama, Vijay, Baker, James R

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Bromo- and thiomaleimides as a new class of thiol-mediated fluorescence 'turn-on' reagents von Youziel, Judith, Akhbar, Ahmed R, Aziz, Qadeer, Smith, Mark E B, Caddick, Stephen, Tinker, Andrew, Baker, James R

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Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells von Moody, Paul, Smith, Mark. E. B., Ryan, Chris P., Chudasama, Vijay, Baker, James R., Molloy, Justin, Caddick, Stephen

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Bromomaleimides: new reagents for the selective and reversible modification of cysteine von Tedaldi, Lauren M, Smith, Mark E B, Nathani, Ramiz I, Baker, James R

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A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy von Maruani, Antoine, Smith, Mark E.B., Miranda, Enrique, Chester, Kerry A., Chudasama, Vijay, Caddick, Stephen

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A rapid, site-selective and efficient route to the dual modification of DARPins von Moody, Paul, Chudasama, Vijay, Nathani, Ramiz I, Maruani, Antoine, Martin, Stephen, Smith, Mark E B, Caddick, Stephen

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In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation von Schumacher, Felix F, Nobles, Muriel, Ryan, Chris P, Smith, Mark E. B, Tinker, Andrew, Caddick, Stephen, Baker, James R

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