PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding von Tinworth, Christopher P, Lithgow, Hannah, Dittus, Lars, Bassi, Zuni I, Hughes, Sophie E, Muelbaier, Marcel, Dai, Han, Smith, Ian E. D, Kerr, William J, Burley, Glenn A, Bantscheff, Marcus, Harling, John D

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Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 von Mares, Alina, Miah, Afjal H., Smith, Ian E. D., Rackham, Mark, Thawani, Aditya R., Cryan, Jenni, Haile, Pamela A., Votta, Bartholomew J., Beal, Allison M., Capriotti, Carol, Reilly, Michael A., Fisher, Don T., Zinn, Nico, Bantscheff, Marcus, MacDonald, Thomas T., Vossenkamper, Anna, Dace, Phoebe, Churcher, Ian, Benowitz, Andrew B., Watt, Gillian, Denyer, Jane, Scott-Stevens, Paul, Harling, John D.

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Optimization of a Series of RIPK2 PROTACs von Miah, Afjal H, Smith, Ian E. D, Rackham, Mark, Mares, Alina, Thawani, Aditya R, Nagilla, Rakesh, Haile, Pamela A, Votta, Bartholomew J, Gordon, Laurie J, Watt, Gillian, Denyer, Jane, Fisher, Don T, Dace, Phoebe, Giffen, Paul, Goncalves, Andrea, Churcher, Ian, Scott-Stevens, Paul, Harling, John D

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Differing needs for Advance Care Planning in the Veterans Health Administration: use of latent class analysis to identify subgroups to enhance Advance Care Planning via Group Visit... von Matthieu, Monica M, Ounpraseuth, Songthip T, Williams, J Silas, Hu, Bo, Adkins, David A, Oliver, Ciara M, Taylor, Laura D, McCullough, Jane Ann, Mallory, Mary J, Smith, Ian D, Suarez, Jack H, Garner, Kimberly K

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Adopting the RE-AIM analytic framework for rural program evaluation: experiences from the Advance Care Planning via Group Visits (ACP-GV) national evaluation von Matthieu, Monica M, Taylor, Laura D, Adkins, David A, Williams, J Silas, Hu, Bo, Oliver, Ciara M, McCullough, Jane Ann, Mallory, Mary J, Smith, Ian D, Painter, Jacob T, Ounpraseuth, Songthip T, Garner, Kimberly K

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Induction voltage adders and the induction accelerator family von Smith, Ian D.

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Direct preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes von Donohoe, Timothy J, Kabeshov, Mikhail A, Rathi, Akshat H, Smith, Ian E D

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Catalytic in vivo protein knockdown by small-molecule PROTACs von Bondeson, Daniel P, Mares, Alina, Smith, Ian E D, Ko, Eunhwa, Campos, Sebastien, Miah, Afjal H, Mulholland, Katie E, Routly, Natasha, Buckley, Dennis L, Gustafson, Jeffrey L, Zinn, Nico, Grandi, Paola, Shimamura, Satoko, Bergamini, Giovanna, Faelth-Savitski, Maria, Bantscheff, Marcus, Cox, Carly, Gordon, Deborah A, Willard, Ryan R, Flanagan, John J, Casillas, Linda N, Votta, Bartholomew J, den Besten, Willem, Famm, Kristoffer, Kruidenier, Laurens, Carter, Paul S, Harling, John D, Churcher, Ian, Crews, Craig M

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Pyridyl-2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists: Synthesis, Pharmacokinetics, and In Vivo Potency von Borthwick, Alan D, Liddle, John, Davies, Dave E, Exall, Anne M, Hamlett, Christopher, Hickey, Deirdre M, Mason, Andrew M, Smith, Ian E. D, Nerozzi, Fabrizio, Peace, Simon, Pollard, Derek, Sollis, Steve L, Allen, Michael J, Woollard, Patrick M, Pullen, Mark A, Westfall, Timothy D, Stanislaus, Dinesh J

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Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy von Alder, Catherine M, Ambler, Martin, Campbell, Amanda J, Champigny, Aurelie C, Deakin, Angela M, Harling, John D, Harris, Carol A, Longstaff, Tim, Lynn, Sean, Maxwell, Aoife C, Mooney, Chris J, Scullion, Callum, Singh, Onkar M. P, Smith, Ian E. D, Somers, Donald O, Tame, Christopher J, Wayne, Gareth, Wilson, Caroline, Woolven, James M

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JOLT: a highly directive, very intensive, impulse-like radiator von Baum, C.E., McLemore, D.M., Abdalla, M.D., Skipper, M.C., Baker, W.L., Prather, W.D., Lehr, J.M., O'Loughlin, J.P., Giri, D.V., Smith, I.D., Altes, R., Fockler, J.

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The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors von Deaton, David N., Do, Young, Holt, Jason, Jeune, Michael R., Kramer, H. Fritz, Larkin, Andrew L., Orband-Miller, Lisa A., Peckham, Gregory E., Poole, Chuck, Price, Daniel J., Schaller, Lee T., Shen, Ying, Shewchuk, Lisa M., Stewart, Eugene L., Stuart, J. Darren, Thomson, Stephen A., Ward, Paris, Wilson, Joseph W., Xu, Tianshun, Guss, Jeffrey H., Musetti, Caterina, Rendina, Alan R., Affleck, Karen, Anders, David, Hancock, Ashley P., Hobbs, Heather, Hodgson, Simon T., Hutchinson, Jonathan, Leveridge, Melanie V., Nicholls, Harry, Smith, Ian E.D., Somers, Don O., Sneddon, Helen F., Uddin, Sorif, Cleasby, Anne, Mortenson, Paul N., Richardson, Caroline, Saxty, Gordon

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A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications von Stacey, Peter, Lithgow, Hannah, Lewell, Xiao, Konopacka, Agnieszka, Besley, Stephen, Green, Georgina, Whatling, Ryan, Law, Robert, Röth, Sascha, Sapkota, Gopal P., Smith, Ian E.D., Burley, Glenn A., Harling, John, Benowitz, Andrew B., Queisser, Markus A., Muelbaier, Marcel

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Pulsed power for a rep-rate, electron beam pumped KrF laser von Sethian, J.D., Myers, M., Smith, I.D., Carboni, V., Kishi, J., Morton, D., Pearce, J., Bowen, B., Schlitt, L., Barr, O., Webster, W.

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Role of the subthalamic nucleus in the regulation of nigral dopamine neuron activity von Smith, Ian D., Grace, Anthony A.

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11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial von Cameron, David, Prof, Piccart-Gebhart, Martine J, PhD, Gelber, Richard D, PhD, Procter, Marion, PhD, Goldhirsch, Aron, MD, de Azambuja, Evandro, MD, Castro, Gilberto, MD, Untch, Michael, MD, Smith, Ian, MD, Gianni, Luca, MD, Baselga, Jose, MD, Al-Sakaff, Nedal, PhD, Lauer, Sabine, PhD, McFadden, Eleanor, MA, Leyland-Jones, Brian, MBBS, Bell, Richard, MBBS, Dowsett, Mitch, PhD, Jackisch, Christian, MD

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Design of a radiographic integrated test stand (RITS) based on a voltage adder, to drive a diode immersed in a high magnetic field von Smith, I.D., Bailey, V.L., Fockler, J., Gustwiller, J.S., Johnson, D.L., Maenchen, J.E., Droemer, D.W.

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Impairments in working memory associated with naturalistic dieting in women: no relationship between task performance and urinary 5-HIAA levels von Green, Michael W., Jones, A.David, Smith, Ian D., Cobain, Mark R., Williams, J.Mark G., Healy, Helen, Cowen, Philip J., Powell, Jonathan, Durlach, Paula J.

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Selumetinib plus docetaxel for KRAS -mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study von Jänne, Pasi A, Dr, Shaw, Alice T, MD, Pereira, José Rodrigues, MD, Jeannin, Gaëlle, MD, Vansteenkiste, Johan, Prof, Barrios, Carlos, MD, Franke, Fabio Andre, MD, Grinsted, Lynda, MSc, Zazulina, Victoria, MD, Smith, Paul, PhD, Smith, Ian, MD, Crinò, Lucio, Prof

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Design, fabrication, and testing of a paraboloidal reflector antenna and pulser system for impulse-like waveforms von Giri, D.V., Lackner, H., Smith, I.D., Morton, D.W., Baum, C.E., Marek, J.R., Prather, W.D., Scholfield, D.W.

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