The IL-1 family: regulators of immunity von Sims, John E, Smith, Dirk E

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The biological paths of IL-1 family members IL-18 and IL-33 von Smith, Dirk E.

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IL-33 meets allergens at the gate von Smith, Dirk E.

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Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity von Chang, Ya-Jen, Kim, Hye Young, Albacker, Lee A, Baumgarth, Nicole, McKenzie, Andrew N J, Smith, Dirk E, DeKruyff, Rosemarie H, Umetsu, Dale T

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Cutting Edge: The ST2 Ligand IL-33 Potently Activates and Drives Maturation of Human Mast Cells von Allakhverdi, Zoulfia, Smith, Dirk E, Comeau, Michael R, Delespesse, Guy

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IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms von Hung, Li-Yin, Lewkowich, Ian P., Dawson, Lucas A., Downey, Jordan, Yang, Yanfen, Smith, Dirk E., Herbert, De'Broski R.

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Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity von Kim, Hye Young, PhD, Chang, Ya-Jen, PhD, Subramanian, Srividya, PhD, Lee, Hyun-Hee, PhD, Albacker, Lee A., PhD, Matangkasombut, Ponpan, MD, PhD, Savage, Paul B., PhD, McKenzie, Andrew N.J., PhD, Smith, Dirk E., MS, Rottman, James B., DVM, PhD, DeKruyff, Rosemarie H., PhD, Umetsu, Dale T., MD, PhD

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Neuron-specific effects of interleukin-1β are mediated by a novel isoform of the IL-1 receptor accessory protein von Huang, Yangyang, Smith, Dirk E, Ibáñez-Sandoval, Osvaldo, Sims, John E, Friedman, Wilma J

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Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection von Wills-Karp, Marsha, Rani, Reena, Dienger, Krista, Lewkowich, Ian, Fox, James G, Perkins, Charles, Lewis, Lauren, Finkelman, Fred D, Smith, Dirk E, Bryce, Paul J, Kurt-Jones, Evelyn A, Wang, Timothy C, Sivaprasad, Umasundari, Hershey, Gurjit K, Herbert, De'Broski R

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Large scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes von Tyler, Matthew A., MD, Russell, Chris B., PhD, Smith, Dirk E., MSc, Rottman, James B., DVM, PhD, Padro Dietz, Caroline J., PhD, Hu, Xuguang, PhD, Citardi, Martin J., MD, Fakhri, Samer, MD, Assassi, Shervin, MD, Luong, Amber, MD, PhD

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CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation von Allakhverdi, Zoulfia, PhD, Comeau, Michael R., BSc, Smith, Dirk E., MSc, Toy, Dean, MSc, Endam, Leandra Mfuna, MSc, Desrosiers, Martin, MD, Liu, Yong-Jun, MD, PhD, Howie, Karen J., MSc, Denburg, Judah A., MD, Gauvreau, Gail M., PhD, Delespesse, Guy, MD, PhD

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A new mouse strain for the analysis of invariant NKT cell function von Chandra, Shilpi, Zhao, Meng, Budelsky, Alison, de Mingo Pulido, Alvaro, Day, Jeremy, Fu, Zheng, Siegel, Lori, Smith, Dirk, Kronenberg, Mitchell

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IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis von De Salvo, Carlo, Wang, Xiao-Ming, Pastorelli, Luca, Mattioli, Benedetta, Omenetti, Sara, Buela, Kristine A, Chowdhry, Saleem, Garg, Rekha R, Goodman, Wendy A, Rodriguez-Palacios, Alex, Smith, Dirk E, Abbott, Derek W, Cominelli, Fabio, Bamias, Giorgos, Xin, Wei, Lee, James J, Vecchi, Maurizio, Pizarro, Theresa T

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Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways von Miner, Kent, Labitzke, Katja, Liu, Benxian, Wang, Paul, Henckels, Kathryn, Gaida, Kevin, Elliott, Robin, Chen, Jian Jeffrey, Liu, Longbin, Leith, Anh, Trueblood, Esther, Hensley, Kelly, Xia, Xing-Zhong, Homann, Oliver, Bennett, Brian, Fiorino, Mike, Whoriskey, John, Yu, Gang, Escobar, Sabine, Wong, Min, Born, Teresa L, Budelsky, Alison, Comeau, Mike, Smith, Dirk, Phillips, Jonathan, Johnston, James A, McGivern, Joseph G, Weikl, Kerstin, Powers, David, Kunzelmann, Karl, Mohn, Deanna, Hochheimer, Andreas, Sullivan, John K

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Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33 von Lai, Ying, PhD, Altemeier, William A., MD, Vandree, John, MD, Piliponsky, Adrian M., PhD, Johnson, Brian, BS, Appel, Cara L., BS, Frevert, Charles W., PhD, Hyde, Dallas M., PhD, Ziegler, Steven F., PhD, Smith, Dirk E., PhD, Henderson, William R., MD, Gelb, Michael H., PhD, Hallstrand, Teal S., MD, MPH

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A Central Nervous System-Restricted Isoform of the Interleukin-1 Receptor Accessory Protein Modulates Neuronal Responses to Interleukin-1 von Smith, Dirk E., Lipsky, Brian P., Russell, Chris, Ketchem, Randal R., Kirchner, Jacqueline, Hensley, Kelly, Huang, Yangyang, Friedman, Wilma J., Boissonneault, Vincent, Plante, Marie-Michèle, Rivest, Serge, Sims, John E.

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The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33 von Palmer, Gaby, Lipsky, Brian P., Smithgall, Molly D., Meininger, David, Siu, Sophia, Talabot-Ayer, Dominique, Gabay, Cem, Smith, Dirk E.

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Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness von Ngoi, Soo Mun, St. Rose, Marie-Clare, Menoret, Antoine M, Smith, Dirk E, Tovey, Michael G, Adler, Adam J, Vella, Anthony T

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction von O'Neill, Luke A. J, Fitzgerald, Katherine A, Palsson-McDermott, Eva M, Bowie, Andrew G, Jefferies, Caroline A, Mansell, Ashley S, Brady, Gareth, Brint, Elizabeth, Dunne, Aisling, Gray, Pearl, Harte, Mary T, McMurray, Diane, Smith, Dirk E, Sims, John E, Bird, Timothy A

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Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency von Martin, Praxedis, Talabot-Ayer, Dominique, Seemayer, Christian Alexander, Vigne, Solenne, Lamacchia, Céline, Rodriguez, Emiliana, Finckh, Axel, Smith, Dirk E, Gabay, Cem, Palmer, Gaby

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