Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedem... von Davie, Rebecca L., Edwards, Hannah J., Evans, D. Michael, Hodgson, Simon T., Stocks, Michael J., Smith, Alun J., Rushbrooke, Louise J., Pethen, Stephen J., Roe, Michael B., Clark, David E., McEwan, Paul A., Hampton, Sally L.

Volltext

An example of designed multiple ligands spanning protein classes: Dual MCH-1R antagonists/DPPIV inhibitors von Gattrell, William T., Sambrook Smith, Colin P., Smith, Alun J.

Volltext

Neurodevelopmental outcomes following late and moderate prematurity: a population-based cohort study von Johnson, Samantha, Evans, T Alun, Draper, Elizabeth S, Field, David J, Manktelow, Bradley N, Marlow, Neil, Matthews, Ruth, Petrou, Stavros, Seaton, Sarah E, Smith, Lucy K, Boyle, Elaine M

Volltext

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase von Würtz, Peter, PhD, Wang, Qin, MSc, Soininen, Pasi, PhD, Kangas, Antti J., MSc, Fatemifar, Ghazaleh, PhD, Tynkkynen, Tuulia, PhD, Tiainen, Mika, PhD, Perola, Markus, MD, PhD, Tillin, Therese, MB BS, Hughes, Alun D., MD, PhD, Mäntyselkä, Pekka, MD, PhD, Kähönen, Mika, MD, PhD, Lehtimäki, Terho, MD, PhD, Sattar, Naveed, MD, PhD, Hingorani, Aroon D., MD, PhD, Casas, Juan-Pablo, MD, PhD, Salomaa, Veikko, MD, PhD, Kivimäki, Mika, PhD, Järvelin, Marjo-Riitta, MD, PhD, Davey Smith, George, MD, DSc, Vanhala, Mauno, MD, PhD, Lawlor, Debbie A., MD, PhD, Raitakari, Olli T., MD, PhD, Chaturvedi, Nish, MD, PhD, Kettunen, Johannes, PhD, Ala-Korpela, Mika, PhD

Volltext

Blood pressure variability and night-time dipping assessed by 24-hour ambulatory monitoring: Cross-sectional association with cardiac structure in adolescents von Goudswaard, Lucy J, Harrison, Sean, Van De Klee, Daniel, Chaturvedi, Nishi, Lawlor, Debbie A, Davey Smith, George, Hughes, Alun D, Howe, Laura D

Volltext

The Hybrid Algorithm for Treating Chronic Total Occlusions in Europe: The RECHARGE Registry von Maeremans, Joren, Walsh, Simon, Knaapen, Paul, Spratt, James C, Avran, Alexandre, Hanratty, Colm G, Faurie, Benjamin, Agostoni, Pierfrancesco, Bressollette, Erwan, Kayaert, Peter, Bagnall, Alan J, Egred, Mohaned, Smith, Dave, Chase, Alexander, McEntegart, Margaret B, Smith, William H T, Harcombe, Alun, Kelly, Paul, Irving, John, Smith, Elliot J, Strange, Julian W, Dens, Joseph

Volltext

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation von Hemani, Gibran, Dekkers, Koen F., Castillo-Fernandez, Juan, Luijk, René, Carnero-Montoro, Elena, Lawson, Daniel J., Burrows, Kimberley, Suderman, Matthew, Bretherick, Andrew D., Richardson, Tom G., Klughammer, Johanna, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, Ho, Karen M., Söderhäll, Cilla, Soriano-Tárraga, Carolina, Giralt-Steinhauer, Eva, Corcoran, David L., Sugden, Karen, Kasela, Silva, Cardona, Alexia, Day, Felix R., Viberti, Clara, Lerro, Michael, Mandaviya, Pooja, Zeng, Yanni, Clarke, Toni-Kim, Walker, Rosie M., Czamara, Darina, Marioni, Riccardo E., Lin, Tian, Awaloff, Yvonne, Germain, Marine, Aïssi, Dylan, Zwamborn, Ramona, van Eijk, Kristel, Dekker, Annelot, Hottenga, Jouke-Jan, Willemsen, Gonneke, Xu, Cheng-Jian, Barturen, Guillermo, Kerick, Martin, Wang, Carol, Melton, Phillip, Elliott, Hannah R., Shin, Jean, Bernard, Manon, Yet, Idil, Smart, Melissa, Shaw, Chris, Al Chalabi, Ammar, Pershagen, Göran, Melén, Erik, Jiménez-Conde, Jordi, Roquer, Jaume, Montgomery, Grant W., Moffitt, Terrie E., Milani, Lili, Sacerdote, Carlotta, Panico, Salvatore, Caspi, Avshalom, Gagnon, France, Ollikainen, Miina, Kaprio, Jaakko, Felix, Janine F., Rivadeneira, Fernando, Tiemeier, Henning, van IJzendoorn, Marinus H., Uitterlinden, André G., Jaddoe, Vincent W. V., Haley, Chris, Evans, Kathryn L., Murray, Alison, Lahti, Jari, Nohr, Ellen A., Hansen, Torben, Morgen, Camilla S., Bustamante, Mariona, Sunyer, Jordi, Holloway, John W., Zhang, Hongmei, Deary, Ian J., Starr, John M., Beekman, Marian, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, de Geus, Eco J. C., Brunekreef, Bert, Koppelman, Gerard H., Alarcón-Riquelme, Marta E., Ikram, M. Arfan, Hughes, Alun D., Kumari, Meena, Visscher, Peter M., Davey Smith, George, Bock, Christoph, Bell, Jordana T., Relton, Caroline L.

Volltext

Determinants of Intima-Media Thickness in the Young: The ALSPAC Study von Chiesa, Scott T, Charakida, Marietta, Georgiopoulos, Georgios, Dangardt, Frida, Wade, Kaitlin H, Rapala, Alicja, Bhowruth, Devina J, Nguyen, Helen C, Muthurangu, Vivek, Shroff, Rukshana, Davey Smith, George, Lawlor, Debbie A, Sattar, Naveed, Timpson, Nicholas J, Hughes, Alun D, Deanfield, John E

Volltext

Assessing the Causal Role of Body Mass Index on Cardiovascular Health in Young Adults: Mendelian Randomization and Recall-by-Genotype Analyses von Wade, Kaitlin H, Chiesa, Scott T, Hughes, Alun D, Chaturvedi, Nish, Charakida, Marietta, Rapala, Alicja, Muthurangu, Vivek, Khan, Tauseef, Finer, Nicholas, Sattar, Naveed, Howe, Laura D, Fraser, Abigail, Lawlor, Debbie A, Davey Smith, George, Deanfield, John E, Timpson, Nicholas J

Volltext

New Approaches to Marine Conservation Through the Scaling Up of Ecological Data von Edgar, Graham J, Bates, Amanda E, Bird, Tomas J, Jones, Alun H, Kininmonth, Stuart, Stuart-Smith, Rick D, Webb, Thomas J

Volltext

Direct measurements of meltwater runoff on the Greenland ice sheet surface von Smith, Laurence C., Yang, Kang, Pitcher, Lincoln H, Overstreet, Brandon T., Chu, Vena W., Rennermalm, Åsa K., Ryan, Jonathan C., Cooper, Matthew G., Gleason, Colin J., Tedesco, Marco, Jeyaratnam, Jeyavinoth, van As, Dirk, van den Broeke, Michiel R., van de Berg, Willem Jan, Noël, Brice, Langen, Peter L., Cullather, Richard I., Zhao, Bin, Willis, Michael J., Hubbard, Alun, Box, Jason E., Jenner, Brittany A., Behar, Alberto E.

Volltext

Is Height2.7 Appropriate for Indexation of Left Ventricular Mass in Healthy Adolescents? The Importance of Sex Differences von Taylor, Hannah C M, Chaturvedi, Nishi, Davey Smith, George, Ferreira, Diana L S, Fraser, Abigail, Howe, Laura D, Hughes, Alun D, Lawlor, Debbie A, Timpson, Nic J, Park, Chloe M

Volltext

global assembly of adult female mosquito mark-release-recapture data to inform the control of mosquito-borne pathogens von Guerra, Carlos A, Reiner, Robert C, Jr, Perkins, T Alex, Lindsay, Steve W, Midega, Janet T, Brady, Oliver J, Barker, Christopher M, Reisen, William K, Harrington, Laura C, Takken, Willem, Kitron, Uriel, Lloyd, Alun L, Hay, Simon I, Scott, Thomas W, Smith, David L

Volltext

Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 von Swadling, Leo, Diniz, Mariana O., Schmidt, Nathalie M., Amin, Oliver E., Chandran, Aneesh, Shaw, Emily, Pade, Corinna, Gibbons, Joseph M., Le Bert, Nina, Tan, Anthony T., Jeffery-Smith, Anna, Tan, Cedric C. S., Tham, Christine Y. L., Kucykowicz, Stephanie, Aidoo-Micah, Gloryanne, Rosenheim, Joshua, Davies, Jessica, Johnson, Marina, Jensen, Melanie P., Joy, George, McCoy, Laura E., Valdes, Ana M., Chain, Benjamin M., Goldblatt, David, Altmann, Daniel M., Boyton, Rosemary J., Manisty, Charlotte, Treibel, Thomas A., Moon, James C., van Dorp, Lucy, Balloux, Francois, McKnight, Áine, Noursadeghi, Mahdad, Bertoletti, Antonio, Maini, Mala K.

Volltext

Healthy food prescription incentive programme for adults with type 2 diabetes who are experiencing food insecurity: protocol for a randomised controlled trial, modelling and implem... von Olstad, Dana Lee, Beall, Reed, Spackman, Eldon, Dunn, Sharlette, Lipscombe, Lorraine L, Williams, Kienan, Oster, Richard, Scott, Sara, Zimmermann, Gabrielle L, McBrien, Kerry A, Steer, Kieran J D, Chan, Catherine B, Tyminski, Sheila, Berkowitz, Seth, Edwards, Alun L, Saunders-Smith, Terry, Tariq, Saania, Popeski, Naomi, White, Laura, Williamson, Tyler, L'Abbé, Mary, Raine, Kim D, Nejatinamini, Sara, Naser, Aruba, Basualdo-Hammond, Carlota, Norris, Colleen, O’Connell, Petra, Seidel, Judy, Lewanczuk, Richard, Cabaj, Jason, Campbell, David J T

Volltext

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores von Moreno-Grau, Sonia, Grenier-Boley, Benjamin, Andrade, Victor, Duron, Emmanuelle, Küçükali, Fahri, Pasquier, Florence, Sanchez-Garcia, Florentino, Nicolas, Gaël, Selbæk, Geir, Chêne, Geneviève, Hampel, Harald, Bailly, Henri, Zetterberg, Henrik, Alvarez, Ignacio, Appollonio, Ildebrando, Rainero, Innocenzo, Rosas Allende, Irene, Diehl-Schmid, Janine, Van Dongen, Jasper, Bis, Joshua C., Popp, Julius, Deckert, Jürgen, Buerger, Katharina, Fließbach, Klaus, Kilander, Lena, Weinhold, Leonie, Tremolizzo, Lucio, Bellenguez, Céline, Löwenmark, Malin, Hulsman, Marc, Spallazzi, Marco, Quintela, Inés, Dalmasso, Maria Carolina, Martínez-Larrad, María Teresa, Yannakoulia, Mary, Wagner, Michael, Scamosci, Michela, Calero, Miguel, Banaj, Nerisa, Scarmeas, Nikolaos, Hanon, Oliver, Peters, Oliver, Skrobot, Olivia Anna, Dionigi Rossi, Paolo, Holmans, Peter A., Fischer, Peter, Yang, Qiong, Vandenberghe, Rik, Ghidoni, Roberta, Sorbi, Sandro, Helisalmi, Seppo, Cervera-Carles, Laura, Fostinelli, Silvia, Djurovic, Srdjan, Menéndez-González, Manuel, Deramecourt, Vincent, Frank-García, Ana, Kehoe, Patrick Gavin, Sánchez-Juan, Pascual, García-Alberca, Jose María, Real, Luis M., Marquié, Marta, Moreno, Fermin, Amouyel, Philippe, Schellenberg, Gerard D., Sánchez-Valle, Raquel, Serrano-Ríos, Manuel, Andreassen, Ole A, Posthuma, Danielle, Lambert, Jean-Charles, Baquero, Miquel, García-Madrona, Sebastián, García-González, Pablo, Valero, Sergi, Sotolongo-Grau, Oscar, Ullgren, Abbe, Naj, Adam C., Benaque, Alba, Pérez-Cordón, Alba, Benussi, Alberto, Rábano, Alberto, Padovani, Alessandro, Squassina, Alessio, de Mendonça, Alexandre, Meggy, Alun, Schneider, Anja, Corbatón-Anchuelo, Arturo, Borroni, Barbara, Nordestgaard, Børge G., Masullo, Carlo, Martínez Rodríguez, Carmen, Muñoz-Fernandez, Carmen, Dufouil, Carole, Van Broeckhoven, Christine, Holmes, Clive, Buiza-Rueda, Dolores, Aarsland, Dag, Galimberti, Daniela, Scarpini, Elio, Rodriguez-Rodriguez, Eloy

Volltext

Is Height 2.7 Appropriate for Indexation of Left Ventricular Mass in Healthy Adolescents? The Importance of Sex Differences von Taylor, Hannah C M, Chaturvedi, Nishi, Davey Smith, George, Ferreira, Diana L S, Fraser, Abigail, Howe, Laura D, Hughes, Alun D, Lawlor, Debbie A, Timpson, Nic J, Park, Chloe M

Volltext

Updating the study protocol: Insight 46 - a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development - phases 2 and 3 von Murray-Smith, Heidi, Barker, Suzie, Barkhof, Frederik, Barnes, Josephine, Brown, Thomas M, Captur, Gabriella, R E Cartlidge, Molly, Cash, David M, Coath, William, Davis, Daniel, Dickson, John C, Groves, James, Hughes, Alun D, James, Sarah-Naomi, Keshavan, Ashvini, Keuss, Sarah E, King-Robson, Josh, Lu, Kirsty, Malone, Ian B, Nicholas, Jennifer M, Rapala, Alicja, Scott, Catherine J, Street, Rebecca, Sudre, Carole H, Thomas, David L, Wong, Andrew, Wray, Selina, Zetterberg, Henrik, Chaturvedi, Nishi, Fox, Nick C, Crutch, Sebastian J, Richards, Marcus, Schott, Jonathan M

Volltext

Recommendations on the Use of Open Surgical and Endovascular Aneurysm Repair for the Management of Unruptured Abdominal Aortic Aneurysm from the Guideline Development Committee App... von Bradbury, Andrew W., Davies, Alun H., Dhesi, Jugdeep K., Hammond, Christopher J., Hampshire, Mark, Jellett, Karen, Lindridge, Jaqualine, Pichel, Adam C., Ribbons, Tamsin, Ruffell, Les, Slater, Matthew, Smith, Alan H., Trender, Hazel, Tang, Sammer, Wilson, Noel V.

Volltext

Antegrade Dissection and Reentry as Part of the Hybrid Chronic Total Occlusion Revascularization Strategy: A Subanalysis of the RECHARGE Registry (Registry of CrossBoss and Hybrid... von Maeremans, Joren, Dens, Jo, Spratt, James C, Bagnall, Alan J, Stuijfzand, Wynand, Nap, Alexander, Agostoni, Pierfrancesco, Wilson, William, Hanratty, Colm G, Wilson, Simon, Faurie, Benjamin, Avran, Alexandre, Bressollette, Erwan, Egred, Mohaned, Knaapen, Paul, Walsh, Simon

Volltext