Simple and Inexpensive Fluorescence-Based Technique for High-Throughput Antimalarial Drug Screening von SMILKSTEIN, Martin, SRIWILAIJAROEN, Nongluk, KELLY, Jane Xu, WILAIRAT, Prapon, RISCOE, Michael

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Discovery of dual function acridones as a new antimalarial chemotype von Kelly, Jane X., Smilkstein, Martin J., Brun, Reto, Wittlin, Sergio, Cooper, Roland A., Lane, Kristin D., Janowsky, Aaron, Johnson, Robert A., Dodean, Rozalia A., Winter, Rolf, Hinrichs, David J., Riscoe, Michael K.

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Long-acting intramuscular injections of ELQ-331, an antimalarial agent von Karunakaran, Dipu, Mutyam, Shravan K., Fu, Melody, Chen, Jiaming, Pham, Kim Hue Nicky, Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Dodean, Rozalia A., Smilkstein, Martin J., Riscoe, Michael K., Shankar, Gita

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ELQ-331 as a prototype for extremely durable chemoprotection against malaria von Smilkstein, Martin J, Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A, Dodean, Rozalia A, Frueh, Lisa, Hinrichs, David J, Li, Yuexin, Martinson, Thomas, Munar, Myrna Y, Winter, Rolf W, Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R, Kelly, Jane X, Kappe, Stefan H I, Wilder, Brandon K, Riscoe, Michael K

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Antimalarial Activity of Natural and Synthetic Prodiginines von Papireddy, Kancharla, Smilkstein, Martin, Kelly, Jane Xu, Shweta, Salem, Shaimaa M, Alhamadsheh, Mamoun, Haynes, Stuart W, Challis, Gregory L, Reynolds, Kevin A

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Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria von Stickles, Allison M, Smilkstein, Martin J, Morrisey, Joanne M, Li, Yuexin, Forquer, Isaac P, Kelly, Jane X, Pou, Sovitj, Winter, Rolf W, Nilsen, Aaron, Vaidya, Akhil B, Riscoe, Michael K

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Atypical Molecular Basis for Drug Resistance to Mitochondrial Function Inhibitors in Plasmodium falciparum von Painter, Heather J, Morrisey, Joanne M, Mather, Michael W, Orchard, Lindsey M, Luck, Cuyler, Smilkstein, Martin J, Riscoe, Michael K, Vaidya, Akhil B, Llinás, Manuel

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Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro von Janowsky, Aaron, Eshleman, Amy J., Johnson, Robert A., Wolfrum, Katherine M., Hinrichs, David J., Yang, Jongtae, Zabriskie, T. Mark, Smilkstein, Martin J., Riscoe, Michael K.

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Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs von Gunsaru, Bornface, Burgess, Steven J, Morrill, Westin, Kelly, Jane X, Shomloo, Shawheen, Smilkstein, Martin J, Liebman, Katherine, Peyton, David H

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Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifi... von McConnell, Erin V, Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A, Smilkstein, Martin J, Krollenbrock, Alina, Nilsen, Aaron, Zakharov, Lev N, Riscoe, Michael K, Doggett, J Stone

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Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials von Kancharla, Papireddy, Dodean, Rozalia A, Li, Yuexin, Pou, Sovitj, Pybus, Brandon, Melendez, Victor, Read, Lisa, Bane, Charles E, Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J, Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E, Nolan, Christina, Ceja, Frida G, Rasmussen, Stephanie A, Tumwebaze, Patrick K, Rosenthal, Philip J, Mu, Jianbing, Bayles, Brett R, Cooper, Roland A, Reynolds, Kevin A, Smilkstein, Martin J, Riscoe, Michael K, Kelly, Jane X

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Optimization of endochin-like quinolones for antimalarial activity von Winter, Rolf, Kelly, Jane X., Smilkstein, Martin J., Hinrichs, David, Koop, Dennis R., Riscoe, Michael K.

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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials von Dodean, Rozalia A, Kancharla, Papireddy, Li, Yuexin, Melendez, Victor, Read, Lisa, Bane, Charles E, Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J, Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E, Nolan, Christina, Huezo, Stephanie J, Rasmussen, Stephanie A, Stephens, Melissa T, Tan, John C, Cooper, Roland A, Smilkstein, Martin J, Pou, Sovitj, Winter, Rolf W, Riscoe, Michael K, Kelly, Jane X

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A Chloroquine-like Molecule Designed to Reverse Resistance in Plasmodium falciparum von Burgess, Steven J, Selzer, Audrey, Kelly, Jane Xu, Smilkstein, Martin J, Riscoe, Michael K, Peyton, David H

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Antimalarial quinolones: Synthesis, potency, and mechanistic studies von Winter, Rolf W., Kelly, Jane X., Smilkstein, Martin J., Dodean, Rozalia, Hinrichs, David, Riscoe, Michael K.

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3‑Position Biaryl Endochin-like Quinolones with Enhanced Antimalarial Performance von Pou, Sovitj, Winter, Rolf W., Dodean, Rozalia A., Liebman, Katherine, Li, Yuexin, Mather, Michael W., Nepal, Binod, Nilsen, Aaron, Handford, Mason J., Riscoe, Teresa M., Laxson, Sydney, Kirtley, Payton J., Aleshnick, Maya, Zakharov, Lev N., Kelly, Jane X., Smilkstein, Martin J., Wilder, Brandon K., Kortagere, Sandhya, Vaidya, Akhil B., Alday, P. Holland, Doggett, J. Stone, Riscoe, Michael K.

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Design, Synthesis, and Evaluation of 10-N-Substituted Acridones as Novel Chemosensitizers in Plasmodium falciparum von KELLY, Jane X, SMILKSTEIN, Martin J, COOPER, Roland A, LANE, Kristin D, JOHNSON, Robert A, JANOWSKY, Aaron, DODEAN, Rozalia A, HINRICHS, David J, WINTER, Rolf, RISCOE, Michael

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Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria von Frueh, Lisa, Li, Yuexin, Mather, Michael W, Li, Qigui, Pou, Sovitj, Nilsen, Aaron, Winter, Rolf W, Forquer, Isaac P, Pershing, April M, Xie, Lisa H, Smilkstein, Martin J, Caridha, Diana, Koop, Dennis R, Campbell, Robert F, Sciotti, Richard J, Kreishman-Deitrick, Mara, Kelly, Jane X, Vesely, Brian, Vaidya, Akhil B, Riscoe, Michael K

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Evaluation and lead optimization of anti-malarial acridones von Winter, Rolf W., Kelly, Jane X., Smilkstein, Martin J., Dodean, Rozalia, Bagby, Grover C., Rathbun, R. Keaney, Levin, Joshua I., Hinrichs, David, Riscoe, Michael K.

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Targeted Structure–Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc 1 and Identif... von McConnell, Erin V, Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A, Smilkstein, Martin J, Krollenbrock, Alina, Nilsen, Aaron, Zakharov, Lev N, Riscoe, Michael K, Doggett, J. Stone

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