Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum von Wilson, DW, Goodman, CD, Sleebs, BE, Weiss, GE, de Jong, NWM, Angrisano, F, Langer, C, Baum, J, Crabb, BS, Gilson, PR, McFadden, GI, Beeson, JG

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Isolation and structural analysis of the covalent adduct formed between a bis-amino mitoxantrone analogue and DNA: a pathway to major–minor groove cross-linked adducts von Konda, SK, Kelso, C, Medan, J, Sleebs, BE, Phillips, DR, Cutts, SM, Collins, JG, Collins, Grant

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Synthesis of Acyl Phosphoramidates Employing a Modified Staudinger Reaction von Currie, Iain, Sleebs, Brad E.

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A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell von Gabriela, Mikha, Matthews, Kathryn M, Boshoven, Cas, Kouskousis, Betty, Jonsdottir, Thorey K, Bullen, Hayley E, Modak, Joyanta, Steer, David L, Sleebs, Brad E, Crabb, Brendan S, Koning-Ward, Tania F de, Gilson, Paul R

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Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery von Duffy, Sandra, Sykes, Melissa L, Jones, Amy J, Shelper, Todd B, Simpson, Moana, Lang, Rebecca, Poulsen, Sally-Ann, Sleebs, Brad E, Avery, Vicky M

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Mitoxantrone, More than Just Another Topoisomerase II Poison von Evison, Benny J., Sleebs, Brad E., Watson, Keith G., Phillips, Don R., Cutts, Suzanne M.

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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites von Sleebs, Brad E, Lopaticki, Sash, Marapana, Danushka S, O'Neill, Matthew T, Rajasekaran, Pravin, Gazdik, Michelle, Günther, Svenja, Whitehead, Lachlan W, Lowes, Kym N, Barfod, Lea, Hviid, Lars, Shaw, Philip J, Hodder, Anthony N, Smith, Brian J, Cowman, Alan F, Boddey, Justin A

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Chemo-proteomics in antimalarial target identification and engagement von Bailey, Brodie L, Nguyen, William, Cowman, Alan F, Sleebs, Brad E

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An appraisal of natural products active against parasitic nematodes of animals von Garcia-Bustos, Jose F, Sleebs, Brad E, Gasser, Robin B

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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle von Favuzza, Paola, de Lera Ruiz, Manuel, Thompson, Jennifer K., Triglia, Tony, Ngo, Anna, Steel, Ryan W.J., Vavrek, Marissa, Christensen, Janni, Healer, Julie, Boyce, Christopher, Guo, Zhuyan, Hu, Mengwei, Khan, Tanweer, Murgolo, Nicholas, Zhao, Lianyun, Penington, Jocelyn Sietsma, Reaksudsan, Kitsanapong, Jarman, Kate, Dietrich, Melanie H., Richardson, Lachlan, Guo, Kai-Yuan, Lopaticki, Sash, Tham, Wai-Hong, Rottmann, Matthias, Papenfuss, Tony, Robbins, Jonathan A., Boddey, Justin A., Sleebs, Brad E., Sabroux, Hélène Jousset, McCauley, John A., Olsen, David B., Cowman, Alan F.

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Role of Plasmepsin V in Export of Diverse Protein Families from the Plasmodium falciparum Exportome von Boddey, Justin A., Carvalho, Teresa G., Hodder, Anthony N., Sargeant, Tobias J., Sleebs, Brad E., Marapana, Danushka, Lopaticki, Sash, Nebl, Thomas, Cowman, Alan F.

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Late Stage Phosphotyrosine Mimetic Functionalization of Peptides Employing Metallaphotoredox Catalysis von Chen, Hao, Mao, Runyu, Brzozowski, Martin, Nguyen, Nghi H, Sleebs, Brad E

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The Development Process for Discovery and Clinical Advancement of Modern Antimalarials von Ashton, Trent D, Devine, Shane M, Möhrle, Jörg J, Laleu, Benoît, Burrows, Jeremy N, Charman, Susan A, Creek, Darren J, Sleebs, Brad E

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Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868 von Taki, Aya C., Wang, Tao, Nguyen, Nghi N., Ang, Ching-Seng, Leeming, Michael G., Nie, Shuai, Byrne, Joseph J., Young, Neil D., Zheng, Yuanting, Ma, Guangxu, Korhonen, Pasi K., Koehler, Anson V., Williamson, Nicholas A., Hofmann, Andreas, Chang, Bill C. H., Häberli, Cécile, Keiser, Jennifer, Jabbar, Abdul, Sleebs, Brad E., Gasser, Robin B.

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Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of Haemonchus contortus In Vitro von Herath, H. M. P. Dilrukshi, Taki, Aya C., Nghi Nguyen, Garcia-Bustos, Jose, Hofmann, Andreas, Wang, Tao, Ma, Guangxu, Chang, Bill C. H., Jabbar, Abdul, Sleebs, Brad E., Gasser, Robin B.

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Structure-guided design of a selective BCL-XL inhibitor von Lessene, Guillaume, Czabotar, Peter E, Sleebs, Brad E, Zobel, Kerry, Lowes, Kym N, Adams, Jerry M, Baell, Jonathan B, Colman, Peter M, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Gibbons, Paul, Kersten, Wilhelmus J A, Kulasegaram, Sanji, Moss, Rebecca M, Parisot, John P, Smith, Brian J, Street, Ian P, Yang, Hong, Huang, David C S, Watson, Keith G

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A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity von Shanley, Harrison T, Taki, Aya C, Byrne, Joseph J, Nguyen, Nghi, Wells, Tim N C, Jabbar, Abdul, Sleebs, Brad E, Gasser, Robin B

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Inhibition of Plasmepsin V Activity Blocks Plasmodium falciparum Gametocytogenesis and Transmission to Mosquitoes von Jennison, Charlie, Lucantoni, Leonardo, O’Neill, Matthew T., McConville, Robyn, Erickson, Sara M., Cowman, Alan F., Sleebs, Brad E., Avery, Vicky M., Boddey, Justin A.

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An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell von Coffey, Michael J, Sleebs, Brad E, Uboldi, Alessandro D, Garnham, Alexandra, Franco, Magdalena, Marino, Nicole D, Panas, Michael W, Ferguson, David Jp, Enciso, Marta, O'Neill, Matthew T, Lopaticki, Sash, Stewart, Rebecca J, Dewson, Grant, Smyth, Gordon K, Smith, Brian J, Masters, Seth L, Boothroyd, John C, Boddey, Justin A, Tonkin, Christopher J

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High-Throughput Phenotypic Assay to Screen for Anthelmintic Activity on Haemonchus contortus von Taki, Aya C., Byrne, Joseph J., Wang, Tao, Sleebs, Brad E., Nguyen, Nghi, Hall, Ross S., Korhonen, Pasi K., Chang, Bill C. H., Jackson, Paul, Jabbar, Abdul, Gasser, Robin B.

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