C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector von Abudayyeh, Omar O., Gootenberg, Jonathan S., Konermann, Silvana, Joung, Julia, Slaymaker, Ian M., Cox, David B. T., Shmakov, Sergey, Makarova, Kira S., Semenova, Ekaterina, Minakhin, Leonid, Severinov, Konstantin, Regev, Aviv, Lander, Eric S., Koonin, Eugene V., Zhang, Feng

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Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System von Zetsche, Bernd, Gootenberg, Jonathan S., Abudayyeh, Omar O., Slaymaker, Ian M., Makarova, Kira S., Essletzbichler, Patrick, Volz, Sara E., Joung, Julia, van der Oost, John, Regev, Aviv, Koonin, Eugene V., Zhang, Feng

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Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA von Yamano, Takashi, Nishimasu, Hiroshi, Zetsche, Bernd, Hirano, Hisato, Slaymaker, Ian M., Li, Yinqing, Fedorova, Iana, Nakane, Takanori, Makarova, Kira S., Koonin, Eugene V., Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu

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Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28 von Smargon, Aaron A., Cox, David B.T., Pyzocha, Neena K., Zheng, Kaijie, Slaymaker, Ian M., Gootenberg, Jonathan S., Abudayyeh, Omar A., Essletzbichler, Patrick, Shmakov, Sergey, Makarova, Kira S., Koonin, Eugene V., Zhang, Feng

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Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits von Platt, Randall J., Zhou, Yang, Slaymaker, Ian M., Shetty, Ashwin S., Weisbach, Niels R., Kim, Jin-Ah, Sharma, Jitendra, Desai, Mitul, Sood, Sabina, Kempton, Hannah R., Crabtree, Gerald R., Feng, Guoping, Zhang, Feng

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High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage von Slaymaker, Ian M., Mesa, Pablo, Kellner, Max J., Kannan, Soumya, Brignole, Edward, Koob, Jeremy, Feliciano, Patricia R., Stella, Stefano, Abudayyeh, Omar O., Gootenberg, Jonathan S., Strecker, Jonathan, Montoya, Guillermo, Zhang, Feng

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Base editing: advances and therapeutic opportunities von Porto, Elizabeth M., Komor, Alexis C., Slaymaker, Ian M., Yeo, Gene W.

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Rationally engineered Cas9 nucleases with improved specificity von Slaymaker, Ian M., Gao, Linyi, Zetsche, Bernd, Scott, David A., Yan, Winston X., Zhang, Feng

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High-resolution structure of cas13b and biochemical characterization of RNA targeting and cleavage von Slaymaker, Ian M., Mesa, Pablo, Kellner, Max J., Kannan, Soumya, Brignole, Edward, Koob, Jeremy, Feliciano, Patricia R., Stella, Stefano, Abudayyeh, Omar O., Gootenberg, Jonathan S., Strecker, Jonathan, Montoya, Guillermo, Zhang, Feng

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Engineering Cas9 for human genome editing von Slaymaker, Ian M., Gaudelli, Nicole M.

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Directed evolution of adenine base editors with increased activity and therapeutic application von Gaudelli, Nicole M., Lam, Dieter K., Rees, Holly A., Solá-Esteves, Noris M., Barrera, Luis A., Born, David A., Edwards, Aaron, Gehrke, Jason M., Lee, Seung-Joo, Liquori, Alexander J., Murray, Ryan, Packer, Michael S., Rinaldi, Conrad, Slaymaker, Ian M., Yen, Jonathan, Young, Lauren E., Ciaramella, Giuseppe

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The 1.8-Å Crystal Structure of the N-Terminal Domain of an Archaeal MCM as a Right-Handed Filament von Fu, Yang, Slaymaker, Ian M., Wang, Junfeng, Wang, Ganggang, Chen, Xiaojiang S.

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CRISPR–Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling von Tangprasertchai, Narin S, Di Felice, Rosa, Zhang, Xiaojun, Slaymaker, Ian M, Vazquez Reyes, Carolina, Jiang, Wei, Rohs, Remo, Qin, Peter Z

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Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology von Slaymaker, Ian M, Fu, Yang, Toso, Daniel B, Ranatunga, Nimna, Brewster, Aaron, Forsburg, Susan L, Zhou, Z Hong, Chen, Xiaojiang S

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Towards secure Grid-enabled healthcare von Power, D. J., Politou, E. A., Slaymaker, M. A., Simpson, A. C.

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Securing web services for deployment in health grids von Power, D.J., Politou, E.A., Slaymaker, M.A., Simpson, A.C.

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Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA binding von Brewster, Aaron S, Slaymaker, Ian M, Afif, Samir A, Chen, Xiaojiang S

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GIMI: generic infrastructure for medical informatics von Simpson, A., Power, D., Slaymaker, M., Politou, E.

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Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase von Slaymaker, Ian M., Bracey, Michael, Mileni, Mauro, Garfunkle, Joie, Cravatt, Benjamin F., Boger, Dale L., Stevens, Raymond C.

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Security Aspects of Grid-based Digital Mammography von Slaymaker, M. A., Politou, E., Power, D. J., Lloyd, S., Simpson, A. C.

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