Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms von Palliyaguru, Dushani L., Chartoumpekis, Dionysios V., Wakabayashi, Nobunao, Skoko, John J., Yagishita, Yoko, Singh, Shivendra V., Kensler, Thomas W.

Volltext

Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet von Slocum, Stephen L., Skoko, John J., Wakabayashi, Nobunao, Aja, Susan, Yamamoto, Masayuki, Kensler, Thomas W., Chartoumpekis, Dionysios V.

Volltext

Notch-Nrf2 Axis: Regulation of Nrf2 Gene Expression and Cytoprotection by Notch Signaling von Wakabayashi, Nobunao, Skoko, John J., Chartoumpekis, Dionysios V., Kimura, Shoko, Slocum, Stephen L., Noda, Kentaro, Palliyaguru, Dushani L., Fujimuro, Masahiro, Boley, Patricia A., Tanaka, Yugo, Shigemura, Norihisa, Biswal, Shyam, Yamamoto, Masayuki, Kensler, Thomas W.

Volltext

Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer von Attaran, Shireen, Skoko, John J., Hopkins, Barbara L., Wright, Megan K., Wood, Laurel E., Asan, Alparslan, Woo, Hyun Ae, Feinberg, Adam, Neumann, Carola A.

Volltext

The peroxidase PRDX1 inhibits the activated phenotype in mammary fibroblasts through regulating c-Jun N-terminal kinases von Jezierska-Drutel, Agnieszka, Attaran, Shireen, Hopkins, Barbara L, Skoko, John J, Rosenzweig, Steven A, Neumann, Carola A

Volltext

Signals Getting Crossed in the Entanglement of Redox and Phosphorylation Pathways: Phosphorylation of Peroxiredoxin Proteins Sparks Cell Signaling von Skoko, John J, Attaran, Shireen, Neumann, Carola A

Volltext

Mimicking Embedded Vasculature Structure for 3D Cancer on a Chip Approaches through Micromilling von Wan, L., Skoko, J., Yu, J., Ozdoganlar, O. B., LeDuc, P. R., Neumann, C. A.

Volltext

A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells von Vogt, Andreas, McDonald, Peter R, Tamewitz, Aletheia, Sikorski, Rachel P, Wipf, Peter, Skoko, 3rd, John J, Lazo, John S

Volltext

Redox regulation of RAD51 Cys319 and homologous recombination by peroxiredoxin 1 von Skoko, John J., Cao, Juxiang, Gaboriau, David, Attar, Myriam, Asan, Alparslan, Hong, Lisa, Paulsen, Candice E., Ma, Hongqiang, Liu, Yang, Wu, Hanzhi, Harkness, Trey, Furdui, Cristina M., Manevich, Yefim, Morrison, Ciaran G., Brown, Erika T., Normolle, Daniel, Spies, Maria, Spies, Michael Ashley, Carroll, Kate, Neumann, Carola A.

Volltext

Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities von Vázquez Rivera, Alondra, Donald, Heather, Alaoui-El-Azher, Mounia, Skoko, John J, Lazo, John S, Parniak, Michael A, Johnston, Paul A, Sluis-Cremer, Nicolas

Volltext

Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol von Palliyaguru, Dushani L, Yang, Li, Chartoumpekis, Dionysios V, Wendell, Stacy G, Fazzari, Marco, Skoko, John J, Liao, Yong, Oesterreich, Steffi, Michalopoulos, George K, Kensler, Thomas W

Volltext

Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies von Hong, Lisa, Braden, Dennis C., Zhao, Yaoning, Skoko, John J., Chang, Fei, Woodcock, Steven R., Uvalle, Crystall, Casey, Allison, Wood, Katherine, Salvatore, Sonia R., Asan, Alparslan, Harkness, Trey, Fagunloye, Adeola, Razzaghi, Mortezaali, Straub, Adam, Spies, Maria, Brown, Daniel D., Lee, Adrian V., Schopfer, Francisco, Freeman, Bruce A., Neumann, Carola A.

Volltext

When NRF2 talks, who's listening? von Wakabayashi, Nobunao, Slocum, Stephen L, Skoko, John J, Shin, Soona, Kensler, Thomas W

Volltext

Author Correction: Mimicking Embedded Vasculature Structure for 3D Cancer on a Chip Approaches through Micromilling von Wan, L., Skoko, J., Yu, J., Ozdoganlar, O. B., LeDuc, P. R., Neumann, C. A.

Volltext

Peroxiredoxin Involvement in the Initiation and Progression of Human Cancer von Hampton, Mark B, Vick, Kate A, Skoko, John J, Neumann, Carola A

Volltext

A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7 von Hopkins, Barbara L, Nadler, Monica, Skoko, John J, Bertomeu, Thierry, Pelosi, Andrea, Shafaei, Parisa Mousavi, Levine, Kevin, Schempf, Anja, Pennarun, Bodvael, Yang, Bo, Datta, Dipak, Bucur, Octavian, Ndebele, Kenneth, Oesterreich, Steffi, Yang, Da, Giulia Rizzo, Maria, Khosravi-Far, Roya, Neumann, Carola A

Volltext

Development and optimization of high-throughput in vitro protein phosphatase screening assays von Lazo, John S, Tierno, Marni Brisson, Johnston, Paul A, Foster, Caleb, Skoko, John J, Shinde, Sunita N, Shun, Tong Ying

Volltext

Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B von Keinan, Shahar, Paquette, William D, Skoko, John J, Beratan, David N, Yang, Weitao, Shinde, Sunita, Johnston, Paul A, Lazo, John S, Wipf, Peter

Volltext

Endoplasmic reticulum stress signalling – from basic mechanisms to clinical applications von Almanza, Aitor, Carlesso, Antonio, Chintha, Chetan, Creedican, Stuart, Doultsinos, Dimitrios, Leuzzi, Brian, Luís, Andreia, McCarthy, Nicole, Montibeller, Luigi, More, Sanket, Papaioannou, Alexandra, Püschel, Franziska, Sassano, Maria Livia, Skoko, Josip, Agostinis, Patrizia, Belleroche, Jackie, Eriksson, Leif A., Fulda, Simone, Gorman, Adrienne M., Healy, Sandra, Kozlov, Andrey, Muñoz‐Pinedo, Cristina, Rehm, Markus, Chevet, Eric, Samali, Afshin

Volltext

Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity von Skoko, John J, Wakabayashi, Nobunao, Noda, Kentaro, Kimura, Shoko, Tobita, Kimimasa, Shigemura, Norihisa, Tsujita, Tadayuki, Yamamoto, Masayuki, Kensler, Thomas W

Volltext