The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition von Lowe, E.D., Noble, M.E.M., Skamnaki, V.T., Oikonomakos, N.G., Owen, D.J., Johnson, L.N.

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Structural Studies on Phospho-CDK2/Cyclin A Bound to Nitrate, a Transition State Analogue:  Implications for the Protein Kinase Mechanism von Cook, A, Lowe, E. D, Chrysina, E. D, Skamnaki, V. T, Oikonomakos, N. G, Johnson, L. N

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Catalytic Mechanism of Phosphorylase Kinase Probed by Mutational Studies von Skamnaki, V. T, Owen, D. J, Noble, M. E. M, Lowe, E. D, Lowe, G, Oikonomakos, N. G, Johnson, L. N

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The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment von Kantsadi, A.L., Manta, S., Psarra, A.-M.G., Dimopoulou, A., Kiritsis, C., Parmenopoulou, V., Skamnaki, V.T., Zoumpoulakis, P., Zographos, S.E., Leonidas, D.D., Komiotis, D.

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Structural Basis of the Synergistic Inhibition of Glycogen Phosphorylase a by Caffeine and a Potential Antidiabetic Drug von Tsitsanou, Katerina E., Skamnaki, Vicky T., Oikonomakos, Nikos G.

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Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site von Oikonomakos, Nikos G., Schnier, Joachim B., Zographos, Spyros E., Skamnaki, Vicky T., Tsitsanou, Katerina E., Johnson, Louise N.

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A new allosteric site in glycogen phosphorylase b as a target for drug interactions von Oikonomakos, Nikos G, Skamnaki, Vicky T, Tsitsanou, Katerina E, G Gavalas, Nikos, Johnson, Louise N

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Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure von TSITSANOU, KATERINA E., OIKONOMAKOS, NIKOS G., ZOGRAPHOS, SPYROS E., SKAMNAKI, VICKY T., GREGORIOU, MARY, WATSON, KIMBERLY A., JOHNSON, LOUISE N., FLEET, GEORGE W.J.

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Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate von Oikonomakos, N G, Tsitsanou, K E, Zographos, S E, Skamnaki, V T, Goldmann, S, Bischoff, H

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The binding of C5-allcynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment von KANTSADI, A. L, MANTA, S, KOMIOTIS, D, PSARRA, A.-M. G, DIMOPOULOU, A, KIRITSIS, C, PARMENOPOULOU, V, SKAMNAKI, V. T, ZOUMPOULAKIS, P, ZOGRAPHOS, S. E, LEONIDAS, D. D

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Kinetic Characterization of the Double Mutant R148A/E182S of Glycogen Phosphorylase Kinase Catalytic Subunit: The Role of the Activation Loop von Skamnaki, Vicky T, Oikonomakos, Nikos G

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Kinetic and Crystallographic Studies of Glucopyranosylidene Spirothiohydantoin Binding to Glycogen Phosphorylase b von Oikonomakos, Nikos G, Skamnaki, Vicky T, Ösz, Erzsébet, Szilágyi, László, Somsák, László, Docsa, Tibor, Tóth, Béla, Gergely, Pál

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Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarboxylate von OIKONOMAKOS, NIKOS G., TSITSANOU, KATERINA E., ZOGRAPHOS, SPYROS E., SKAMNAKI, VICKY T., GOLDMANN, SIEGFRIED, BISCHOFF, HILMAR

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Cooperative Interactions of the Catalytic Nucleophile and the Catalytic Acid in the Inhibition of β-Glycosidases. Calculations and their validation by comparative kinetic and struc... von Heightman, Tom D., Vasella, Andrea, Tsitsanou, Katerina E., Zographos, Spyros E., Skamnaki, Vicky T., Oikonomakos, Nikos G.

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The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor von Zographos, Spyros E, Oikonomakos, Nikos G, Tsitsanou, Katerina E, Leonidas, Demetrios D, Chrysina, Evangelia D, Skamnaki, Vicky T, Bischoff, Hilmar, Goldmann, Siegfried, Watson, Kimberly A, Johnson, Louise N

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High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl- N -acyl-β-d... von Fischer, Thomas, Koulas, Symeon M, Tsagkarakou, Anastasia S, Kyriakis, Efthimios, Stravodimos, George A, Skamnaki, Vassiliki T, Liggri, Panagiota G V, Zographos, Spyros E, Riedl, Rainer, Leonidas, Demetres D

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Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X‑ray Crystallography von Szabó, Katalin E, Kyriakis, Efthimios, Psarra, Anna-Maria G, Karra, Aikaterini G, Sipos, Ádám, Docsa, Tibor, Stravodimos, George A, Katsidou, Elisabeth, Skamnaki, Vassiliki T, Liggri, Panagiota G. V, Zographos, Spyros E, Mándi, Attila, Király, Sándor Balázs, Kurtán, Tibor, Leonidas, Demetres D, Somsák, László

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The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl... von Kyriakis, Efthimios, Karra, Aikaterini G., Papaioannou, Olga, Solovou, Theodora, Skamnaki, Vassiliki T., Liggri, Panagiota G.V., Zographos, Spyros E., Szennyes, Eszter, Bokor, Éva, Kun, Sándor, Psarra, Anna-Maria G., Somsák, László, Leonidas, Demetres D.

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A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinet... von Kun, Sándor, Begum, Jaida, Kyriakis, Efthimios, Stamati, Evgenia C.V., Barkas, Thomas A., Szennyes, Eszter, Bokor, Éva, Szabó, Katalin E., Stravodimos, George A., Sipos, Ádám, Docsa, Tibor, Gergely, Pál, Moffatt, Colin, Patraskaki, Myrto S., Kokolaki, Maria C., Gkerdi, Alkistis, Skamnaki, Vassiliki T., Leonidas, Demetres D., Somsák, László, Hayes, Joseph M.

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The ammonium sulfate inhibition of human angiogenin von Chatzileontiadou, Demetra S. M., Tsirkone, Vicky G., Dossi, Kyriaki, Kassouni, Aikaterini G., Liggri, Panagiota G. V., Kantsadi, Anastassia L., Stravodimos, George A., Balatsos, Nikolaos A. A., Skamnaki, Vassiliki T., Leonidas, Demetres D.

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