From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations von Veit, Gudio, Avramescu, Radu G, Chiang, Annette N, Houck, Scott A, Cai, Zhiwei, Peters, Kathryn W, Hong, Jeong S, Pollard, Harvey B, Guggino, William B, Balch, William E, Skach, William R, Cutting, Garry R, Frizzell, Raymond A, Sheppard, David N, Cyr, Douglas M, Sorscher, Eric J, Brodsky, Jeffrey L, Lukacs, Gergely L

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CFTR trafficking mutations disrupt cotranslational protein folding by targeting biosynthetic intermediates von Shishido, Hideki, Yoon, Jae Seok, Yang, Zhongying, Skach, William R.

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Translational tuning optimizes nascent protein folding in cells von Kim, Soo Jung, Yoon, Jae Seok, Shishido, Hideki, Yang, Zhongying, Rooney, LeeAnn A., Barral, Jose M., Skach, William R.

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Cotranslational Stabilization of Sec62/63 within the ER Sec61 Translocon Is Controlled by Distinct Substrate-Driven Translocation Events von Conti, Brian J., Devaraneni, Prasanna K., Yang, Zhongying, David, Larry L., Skach, William R.

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Engineered transfer RNAs for suppression of premature termination codons von Lueck, John D., Yoon, Jae Seok, Perales-Puchalt, Alfredo, Mackey, Adam L., Infield, Daniel T., Behlke, Mark A., Pope, Marshall R., Weiner, David B., Skach, William R., McCray, Paul B., Ahern, Christopher A.

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Stepwise Insertion and Inversion of a Type II Signal Anchor Sequence in the Ribosome-Sec61 Translocon Complex von Devaraneni, Prasanna K., Conti, Brian, Matsumura, Yoshihiro, Yang, Zhongying, Johnson, Arthur E., Skach, William R.

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Endoplasmic Reticulum Protein Quality Control Is Determined by Cooperative Interactions between Hsp/c70 Protein and the CHIP E3 Ligase von Matsumura, Yoshihiro, Sakai, Juro, Skach, William R.

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A small molecule high throughput screening platform to profile conformational properties of nascent, ribosome-bound proteins von Shishido, Hideki, Yoon, Jae Seok, Skach, William R.

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Ligand-Driven Vectorial Folding of Ribosome-Bound Human CFTR NBD1 von Khushoo, Amardeep, Yang, Zhongying, Johnson, Arthur E., Skach, William R.

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Mechanisms of CFTR Folding at the Endoplasmic Reticulum von Kim, Soo Jung, Skach, William R

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Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis von Balch, William E, Hutt, Darren M, Herman, David, Rodrigues, Ana P C, Noel, Sabrina, Pilewski, Joseph M, Matteson, Jeanne, Hoch, Ben, Kellner, Wendy, Kelly, Jeffery W, Schmidt, Andre, Thomas, Philip J, Matsumura, Yoshihiro, Skach, William R, Gentzsch, Martina, Riordan, John R, Sorscher, Eric J, Okiyoneda, Tsukasa, Yates, John R, Lukacs, Gergely L, Frizzell, Raymond A, Manning, Gerard, Gottesfeld, Joel M

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expanding role of the ER translocon in membrane protein folding von Skach, William R

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Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation von Matsumura, Yoshihiro, David, Larry L, Skach, William R

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Cellular mechanisms of membrane protein folding von Skach, William R

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Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems von Brodsky, Jeffrey L, Skach, William R

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Cotranslational folding inhibits translocation from within the ribosome–Sec61 translocon complex von Conti, Brian J, Elferich, Johannes, Yang, Zhongying, Shinde, Ujwal, Skach, William R

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Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian In Vitro System von Wahlman, Judit, DeMartino, George N., Skach, William R., Bulleid, Neil J., Brodsky, Jeffrey L., Johnson, Arthur E.

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Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking von Crane, Jonathan M, Van Hoek, Alfred N, Skach, William R, Verkman, A S

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Epstein-Barr Viral BNLF2a Protein Hijacks the Tail-anchored Protein Insertion Machinery to Block Antigen Processing by the Transport Complex TAP von Wycisk, Agnes I., Lin, Jiacheng, Loch, Sandra, Hobohm, Kathleen, Funke, Jessica, Wieneke, Ralph, Koch, Joachim, Skach, William R., Mayerhofer, Peter U., Tampé, Robert

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p97 functions as an auxiliary factor to facilitate TM domain extraction during CFTR ER-associated degradation von Carlson, Eric J, Pitonzo, David, Skach, William R

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