PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here? von Skånland, Sigrid S, Brown, Jennifer R

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Off-label uses of drugs for depression von Skånland, Sigrid S., Cieślar-Pobuda, Artur

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SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis von Ikeda, Fumiyo, Deribe, Yonathan Lissanu, Skånland, Sigrid S., Stieglitz, Benjamin, Grabbe, Caroline, Franz-Wachtel, Mirita, van Wijk, Sjoerd J. L., Goswami, Panchali, Nagy, Vanja, Terzic, Janos, Tokunaga, Fuminori, Androulidaki, Ariadne, Nakagawa, Tomoko, Pasparakis, Manolis, Iwai, Kazuhiro, Sundberg, John P., Schaefer, Liliana, Rittinger, Katrin, Macek, Boris, Dikic, Ivan

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Phospho Flow Cytometry with Fluorescent Cell Barcoding for Single Cell Signaling Analysis and Biomarker Discovery von Skånland, Sigrid S

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Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling von Skånland, Sigrid S, Taskén, Kjetil

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B cell signalling pathways—New targets for precision medicine in chronic lymphocytic leukaemia von Skånland, Sigrid S., Karlsen, Linda, Taskén, Kjetil

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Spatial organization of transmembrane receptor signalling von Bethani, Ioanna, Skånland, Sigrid S, Dikic, Ivan, Acker-Palmer, Amparo

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Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case von Skånland, Sigrid S, Inngjerdingen, Marit, Bendiksen, Henrik, York, Jamie, Spetalen, Signe, Munthe, Ludvig A, Tjønnfjord, Geir E

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Overcoming resistance to targeted therapies in chronic lymphocytic leukemia von Skånland, Sigrid S., Mato, Anthony R.

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Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models von Flobak, Åsmund, Skånland, Sigrid S., Hovig, Eivind, Taskén, Kjetil, Russnes, Hege G.

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Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127 von Montoya, Skye, Bourcier, Jessie, Noviski, Mark, Lu, Hao, Thompson, Meghan C, Chirino, Alexandra, Jahn, Jacob, Sondhi, Anya K, Gajewski, Stefan, Tan, Ying Siow May, Yung, Stephanie, Urban, Aleksandra, Wang, Eric, Han, Cuijuan, Mi, Xiaoli, Kim, Won Jun, Sievers, Quinlan, Auger, Paul, Bousquet, Hugo, Brathaban, Nivetha, Bravo, Brandon, Gessner, Melissa, Guiducci, Cristiana, Iuliano, James N, Kane, Tim, Mukerji, Ratul, Reddy, Panga Jaipal, Powers, Janine, Sanchez Garcia de Los Rios, Mateo, Ye, Jordan, Barrientos Risso, Carla, Tsai, Daniel, Pardo, Gabriel, Notti, Ryan Q, Pardo, Alejandro, Affer, Maurizio, Nawaratne, Vindhya, Totiger, Tulasigeri M, Pena-Velasquez, Camila, Rhodes, Joanna M, Zelenetz, Andrew D, Alencar, Alvaro, Roeker, Lindsey E, Mehta, Sanjoy, Garippa, Ralph, Linley, Adam, Soni, Rajesh Kumar, Skånland, Sigrid S, Brown, Robert J, Mato, Anthony R, Hansen, Gwenn M, Abdel-Wahab, Omar, Taylor, Justin

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Approach to a patient with “double refractory” chronic lymphocytic leukemia: “Double, double toil and trouble” (Shakespeare) von Aronson, Julia H., Skånland, Sigrid S., Roeker, Lindsey E., Thompson, Meghan C., Mato, Anthony R.

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Determining drug dose in the era of targeted therapies: playing it (un)safe? von Skånland, Sigrid S., Tjønnfjord, Geir E.

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NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts von Zhang, Deyi, Harris, Hailey M., Chen, Jonathan, Judy, Jen, James, Gabriella, Kelly, Aileen, McIntosh, Joel, Tenn-McClellan, Austin, Ambing, Eileen, Tan, Ying Siow, Lu, Hao, Gajewski, Stefan, Clifton, Matthew C., Yung, Stephanie, Robbins, Daniel W., Pirooznia, Mehdi, Skånland, Sigrid S., Gaglione, Erika, Mhibik, Maissa, Underbayev, Chingiz, Ahn, Inhye E., Sun, Clare, Herman, Sarah E. M., Noviski, Mark, Wiestner, Adrian

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Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia von Yin, Yanping, Athanasiadis, Paschalis, Karlsen, Linda, Urban, Aleksandra, Xu, Haifeng, Murali, Ishwarya, Fernandes, Stacey M, Arribas, Alberto J, Hilli, Abdul K, Taskén, Kjetil, Bertoni, Francesco, Mato, Anthony R, Normant, Emmanuel, Brown, Jennifer R, Tjønnfjord, Geir E, Aittokallio, Tero, Skånland, Sigrid S

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Mcl‐1 and Bcl‐xL levels predict responsiveness to dual MEK/Bcl‐2 inhibition in B‐cell malignancies von Melvold, Katrine, Giliberto, Mariaserena, Karlsen, Linda, Ayuda‐Durán, Pilar, Hanes, Robert, Holien, Toril, Enserink, Jorrit, Brown, Jennifer R., Tjønnfjord, Geir E., Taskén, Kjetil, Skånland, Sigrid S.

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T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses von Skånland, Sigrid S, Moltu, Kristine, Berge, Torunn, Aandahl, Einar M, Taskén, Kjetil

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An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL von Skånland, Sigrid S., Cremaschi, Andrea, Bendiksen, Henrik, Hermansen, Johanne U., Thimiri Govinda Raj, Deepak B., Munthe, Ludvig A., Tjønnfjord, Geir E., Taskén, Kjetil

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Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically von Giliberto, Mariaserena, Thimiri Govinda Raj, Deepak B., Cremaschi, Andrea, Skånland, Sigrid S., Gade, Alexandra, Tjønnfjord, Geir E., Schjesvold, Fredrik, Munthe, Ludvig A., Taskén, Kjetil

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Immunophenotyping with (phospho)protein profiling and fluorescent cell barcoding for single-cell signaling analysis and biomarker discovery von Hermansen, Johanne U., Yin, Yanping, Rein, Idun Dale, Skånland, Sigrid S.

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