Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase... von Unangst, Paul C, Connor, David T, Cetenko, Wiaczeslaw A, Sorenson, Roderick J, Kostlan, Catherine R, Sircar, Jagadish C, Wright, Clifford D, Schrier, Denis J, Dyer, Richard D

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Novel 2-(Substituted phenyl)benzimidazole Derivatives with Potent Activity against IgE, Cytokines, and CD23 for the Treatment of Allergy and Asthma von Richards, Mark L, Lio, Shirley Cruz, Sinha, Anjana, Tieu, Kenneth K, Sircar, Jagadish C

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Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors von Flynn, Daniel L, Belliotti, Thomas R, Boctor, Amal M, Connor, David T, Kostlan, Catherine R, Nies, Donald E, Ortwine, Daniel F, Schrier, Denis J, Sircar, Jagadish C

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Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selecti... von Sircar, Jagadish C, Kostlan, Catherine R, Gilbertsen, Richard B, Bennett, Mary K, Dong, Mi K, Cetenko, W. J

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Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogs von Woo, Peter W. K, Kostlan, Catherine R, Sircar, Jagadish C, Dong, Mi K, Gilbertsen, Richard B

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Discovery of Potent Cyclic GMP Phosphodiesterase Inhibitors. 2-Pyridyl- and 2-Imidazolylquinazolines Possessing Cyclic GMP Phosphodiesterase and Thromboxane Synthesis Inhibitory Ac... von Lee, Sung J, Konishi, Yoshitaka, Yu, Dingwei T, Miskowski, Tamara A, Riviello, Christopher M, Macina, Orest T, Frierson, Manton R, Kondo, Kigen, Sugitani, Masafumi

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Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955 von Gilbertsen, Richard B., Josyula, Usha, Sircar, Jagadish C., Dong, Ml K., Wen-Shen, Wu, Wilburn, David J., Conroy, Mary Carol

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Activities of Two 9-Deazaguanine Analogue Inhibitors of Purine Nucleoside Phosphorylase, CI-972 and PD 141955, in Vitro and in Vivo von GILBERTSEN, R. B., DONG, M. K., JOSYULA, U., SIRCAR, J. C., WILBURN, D. J., CONROY, M. C.

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Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase von Flynn, D L, Capiris, T, Cetenko, W J, Connor, D T, Dyer, R D, Kostlan, C R, Nies, D E, Schrier, D J, Sircar, J C

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Hydroxylamine analogs of 2,6 di- t-butylphenols: Dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors von Kramer, James B., Capiris, Thomas, Sircar, Jagadish C., Connor, David T., Bornemeier, Dirk A., Dyer, Richard D., Kuipers, Paul J., Kennedy, John A., Wright, Clifford D., Okonkwo, Godwin C.N., Lesch, Mark E., Schrier, Denis J., Boschelli, Diane H.

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Reduction of nitroalkenes to nitroalkanes with aqueous sodium borohydride von Meyers, Albert I, Sircar, J. C

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Preliminary report on 8-amino-9-(2-thienylmethyl)guanine (PD 119,229), a novel and potent purine nucleoside phosphorylase inhibitor von Gilbertsen, R. B., Scott, Mary E., Dong, M. K., Kossarek, L. M., Bennett, M. K., Schrier, D. J., Sircar, J. C.

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8-amino-9-substituted guanines: Potent purine nucleoside phosphorylase (PNP) inhibitors von Sircar, J. C., Kostlan, C. R., Pinter, G. W., Suto, M. J., Bobovski, T. P., Capiris, T., Schwender, C. F., Dong, M. K., Scott, M. E., Bennett, M. K., Kossarek, L. M., Gilbertsen, R. B.

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Inhibitors of human purine nucleoside phosphorylase. Synthesis, purine nucleoside phosphorylase inhibition, and T-cell cytotoxicity of 2,5-diaminothiazolo[5,4-d]pyrimidin-7(6H)-one... von SIRCAR, J. C, SUTO, M. J, SCOTT, M. E, DONG, M. K, GILBERTSEN, R. B

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Aza steroids. VII. 18-Nor-D-homo-8-aza steroids von Sircar, J. C, Meyer, Albert I

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Free-radical bromination of methyl abietate by N-bromosuccinimide and solvolysis of the products von Sircar, J. C, Fisher, Gordon Stewart

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Photochemical reactions of resin acids. Photochemically initiated addition of methanol to abietic acid von Sircar, J. C, Fisher, Gordon Stewart

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Inhibition of soybean lipoxygenase by sulfasalazine and 5-aminosalicylic acid: a possible mode of action in ulcerative colitis von Sircar, Jagadish C., Schwender, Charles F., Carethers, Mary E.

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A small molecule compound (AVP-13358) in Phase I clinical development suppresses experimental allergy in animals via a distinctly Novel mechanism von Richards, M.L., Ludwig, J., Banie, H., Soneff, R.Y., Marcantonio, D., Chatterjee, A., Scholz, W., Sircar, J.C.

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Identification and development of a small molecule compound effective in suppressing early mediators of allergy von Richards, M.L., Cruz, S.C., Banie, H., Tieu, K., Sircar, J.C.

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