Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design von Ogden, Pierce J, Kelsic, Eric D, Sinai, Sam, Church, George M

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Deep diversification of an AAV capsid protein by machine learning von Bryant, Drew H., Bashir, Ali, Sinai, Sam, Jain, Nina K., Ogden, Pierce J., Riley, Patrick F., Church, George M., Colwell, Lucy J., Kelsic, Eric D.

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Turbulent coherent structures and early life below the Kolmogorov scale von Krieger, Madison S., Sinai, Sam, Nowak, Martin A.

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Protein design using structure-based residue preferences von Ding, David, Shaw, Ada Y., Sinai, Sam, Rollins, Nathan, Prywes, Noam, Savage, David F., Laub, Michael T., Marks, Debora S.

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Overcoming Immunological Challenges Limiting Capsid-Mediated Gene Therapy With Machine Learning von Wec, Anna Z., Lin, Kathy S., Kwasnieski, Jamie C., Sinai, Sam, Gerold, Jeff, Kelsic, Eric D.

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Computer simulations of cellular group selection reveal mechanism for sustaining cooperation von Markvoort, Albert J., Sinai, Sam, Nowak, Martin A.

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Prebiotic selection for motifs in a model of template-free elongation of polymers within compartments von Kinsler, Grant, Sinai, Sam, Lee, Nicholas Keone, Nowak, Martin A

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Surveying Mount Improbable: Computational Challenges Facing Evolution von sinai, sam

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Primordial sex facilitates the emergence of evolution von Sinai, Sam, Olejarz, Jason, Neagu, Iulia A., Nowak, Martin A.

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Contrastive losses as generalized models of global epistasis von Brookes, David H, Otwinowski, Jakub, Sinai, Sam

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A primer on model-guided exploration of fitness landscapes for biological sequence design von Sinai, Sam, Kelsic, Eric D

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Forecasting labels under distribution-shift for machine-guided sequence design von Wheelock, Lauren Berk, Malina, Stephen, Gerold, Jeffrey, Sinai, Sam

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VIRAL CAPSID POLYPEPTIDES von SINAI, Sam, KELSIC, Eric, CHURCH, George M

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Contrastive losses as generalized models of global epistasis von Brookes, David H, Otwinowski, Jakub, Sinai, Sam

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SYSTEM AND METHODS FOR PREDICTING FEATURES OF BIOLOGICAL SEQUENCES von SINAI, Sam, WHEELOCK, Lauren, GEROLD, Jeffrey

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Beyond the training set: an intuitive method for detecting distribution shift in model-based optimization von Damani, Farhan, Brookes, David H, Sternlieb, Theodore, Webster, Cameron, Malina, Stephen, Jajoo, Rishi, Lin, Kathy, Sinai, Sam

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VIRAL CAPSID POLYPEPTIDES von SINAI, Sam, KELSIC, Eric, CHURCH, George M

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VIRAL CAPSID POLYPEPTIDES von SINAI, Sam, KELSIC, Eric, CHURCH, George M, OGDEN, Pierce

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VIRAL CAPSID POLYPEPTIDES von SINAI, Sam, KELSIC, Eric, CHURCH, George M

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Turbulent coherent structures and early life below the Kolmogorov scale von Krieger, Madison S, Sinai, Sam, Nowak, Martin A

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