OR27-05 Two-pronged Mediation Of Adrenal Steroidogenesis By Oxytocin von Cheliadinova, Uliana, Pevnev, Georgii, Ryu, Vitaly, Frolinger, Tal, Lee Sims, Steven, Ofer, Moldavski, Korkmaz, Funda, Barak, Orly, Gimenez Roig, Judit, Sultana, Farhath, Kramskiy, Natan, Wizman, Soleii, Orloff, Michelle, Yuen, Tony, Lizneva, Daria, Zaidi, Mone, Gumerova, Anisa

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8524 Pituitary Hormone Dysregulation In Symptomatic Long COVID: A Multi-Center Observational Study von Sims, Steven Lee, Labadzhyan, Artak, Chen, Zijian, Kim, Se Min, Brathwaite, Justin, Cullen, Liam, Koga, Mari, Cheliadinova, Uliana, Hwe, Vivian, Gomez, Daniel, Andriakos, Christine, Melnik, Tanya, Puig-Wong, Elena, Whelan, Shawn, Cheng, Susan, Joung, Sandy, Abelev, Zinoviy, Le, Catherine, Zabner, Rachel, Kawakami, Yasuhiko, Araki, Takako

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8631 Tanycytic TSHR Activation Regulates Blood-Hypothalamus Barrier Plasticity, Ingestive Behavior, Adipose Remodeling, and Body Weight von Cullen, Liam, Suhasha Kannangara, Hasni, Witztum, Ronit, Burgess, JoColl, Miyashita, Sari, Gumerova, Anisa, Korkmaz, Funda, Lee Sims, Steven, Cheliadinova, Uliana, Sultana, Farhath, Pevnev, Georgii, Moldavski, Ofer, Barak, Orly, Rojekar, Satish, Laurencin, Victoria, Frolinger, Tal, Yuen, Tony, Goosens, Ki, Zhou, Weibin, Ryu, Vitaly, Zaidi, Mone

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SAT669 Development And Biophysical Characterization Of A Humanized FSH-blocking Monoclonal Antibody Therapeutic Formulated At An Ultra-high Concentration von Rojekar, Satish, Pallapati, Anusha Rani, Gimenez–Roig, Judit, Sant, Damini, Gera, Sakshi, Korkmaz, Funda, Sultana, Farhath, Barak, Orly, Moldavski, Ofer, Cheliadinova, Uliana, Gumerova, Anisa Azatovna, Miyashita, Sari, Kannangara, Hasni Suhasha, Frolinger, Tal, Witztum, Ronit, Macdonald, Anne, Georgii, Pevnev, Sims, Steven Lee, Caminis, John N, Meseck, Marcia, Ryu, Vitaly, Kim, Se-Min, Lizneva, Daria, Yuen, Tony, Zaidi, Mone

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SAT668 Can We Treat Osteoporosis, Obesity And Neurodegeneration With A Single FSH-blocking Drug? von Rani Pallapati, Anusha Rani, Gimenez-Roig, Judit, Rojekar, Satish, Korkmaz, Funda, Sant, Damini, Barak, Orly, Sultana, Farhath, Moldavski, Ofer, Gumerova, Anisa, Kannangara, Hasni Suhasha, Cheliadinova, Uliana, Rosen, Clifford J, Caminis, John N, Meseck, Marcia, Demambro, Victoria Elise, Sims, Steven Lee, Gera, Sakshi, Witztum, Ronit, Miyashita, Sari, Ryu, Vitaly, Saxena, Mansi, Frolinger, Tal, Macdonald, Anne, Kim, Se-Min, Pevnev, Georgii, Lizneva, Daria, Yuen, Tony, Zaidi, Mone

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High-density volumetric super-resolution microscopy von Daly, Sam, Ferreira Fernandes, João, Bruggeman, Ezra, Handa, Anoushka, Peters, Ruby, Benaissa, Sarah, Zhang, Boya, Beckwith, Joseph S., Sanders, Edward W., Sims, Ruth R., Klenerman, David, Davis, Simon J., O’Holleran, Kevin, Lee, Steven F.

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Six Months of Hybrid Closed-Loop Versus Manual Insulin Delivery With Fingerprick Blood Glucose Monitoring in Adults With Type 1 Diabetes: A Randomized, Controlled Trial von McAuley, Sybil A., Lee, Melissa H., Paldus, Barbora, Vogrin, Sara, de Bock, Martin I., Abraham, Mary B., Bach, Leon A., Burt, Morton G., Cohen, Neale D., Colman, Peter G., Davis, Elizabeth A., Hendrieckx, Christel, Holmes-Walker, D. Jane, Kaye, Joey, Keech, Anthony C., Kumareswaran, Kavita, MacIsaac, Richard J., McCallum, Roland W., Sims, Catriona M., Speight, Jane, Stranks, Stephen N., Sundararajan, Vijaya, Trawley, Steven, Ward, Glenn M., Jenkins, Alicia J., Jones, Timothy W., O'Neal, David N.

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Multiplexed single-cell analysis reveals prognostic and nonprognostic T cell types in human colorectal cancer von Masuda, Kazuya, Kornberg, Adam, Miller, Jonathan, Lin, Sijie, Suek, Nathan, Botella, Theo, Secener, Kerim A, Bacarella, Alyssa M, Cheng, Liang, Ingham, Matthew, Rosario, Vilma, Al-Mazrou, Ahmed M, Lee-Kong, Steven A, Kiran, Ravi P, Stoeckius, Marlon, Smibert, Peter, Del Portillo, Armando, Oberstein, Paul E, Sims, Peter A, Yan, Kelley S, Han, Arnold

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Physical activity-mediated associations between perceived neighborhood social environment and depressive symptoms among Jackson Heart Study participants von Tamura, Kosuke, Langerman, Steven D., Orstad, Stephanie L., Neally, Sam J., Andrews, Marcus R., Ceasar, Joniqua N., Sims, Mario, Lee, Jae E., Powell-Wiley, Tiffany M.

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Improved Satisfaction While Maintaining Safety and High Time in Range (TIR) With a Medtronic Investigational Enhanced Advanced Hybrid Closed-Loop (e-AHCL) System von Yuan, Cheng Yi, Kong, Yee W, Amoore, Tess, Brown, Katrin, Grosman, Benyamin, Jenkins, Alicia, Jones, Hannah, Kurtz, Natalie, Lee, Melissa H, MacIsaac, Richard, Netzer, Emma, Paldus, Barbora, Robinson, Lesley, Roy, Anirban, Sims, Catriona M, Trawley, Steven, Vogrin, Sara, O'Neal, David N

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Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes von Sims, Emily K, Bahnson, Henry T, Nyalwidhe, Julius, Haataja, Leena, Davis, Asa K, Speake, Cate, DiMeglio, Linda A, Blum, Janice, Morris, Margaret A, Mirmira, Raghavendra G, Nadler, Jerry, Mastracci, Teresa L, Marcovina, Santica, Qian, Wei-Jun, Yi, Lian, Swensen, Adam C, Yip-Schneider, Michele, Schmidt, C Max, Considine, Robert V, Arvan, Peter, Greenbaum, Carla J, Evans-Molina, Carmella

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Maintenance and functional regulation of immune memory to COVID-19 vaccines in tissues von Davis-Porada, Julia, George, Alex B., Lam, Nora, Caron, Daniel P., Gray, Joshua I., Huang, Jenny, Hwu, Jennifer, Wells, Steven B., Matsumoto, Rei, Kubota, Masaru, Lee, YoonSeung, Morrison-Colvin, Rory, Jensen, Isaac J., Ural, Basak B., Shaabani, Namir, Weiskopf, Daniela, Grifoni, Alba, Sette, Alessandro, Szabo, Peter A., Teijaro, John R., Sims, Peter A., Farber, Donna L.

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922-P: Improved Satisfaction while Maintaining Safety and High Time in Range (TIR) with a Medtronic Investigational Enhanced Advanced Hybrid Closed-Loop System (eAHCL) von YI YUAN, CHENG, KONG, YEE W., AMOORE, TESS, BROWN, KATRIN, GROSMAN, BENYAMIN, JENKINS, ALICIA, JONES, HANNAH, KURTZ, NATALIE, LEE, MELISSA H., MACISAAC, RICHARD, NETZER, EMMA, PALDUS, BARBORA, ROBINSON, LESLEY, ROY, ANIRBAN, SIMS, CATRIONA M., TRAWLEY, STEVEN, VOGRIN, SARA, O'NEAL, DAVID N.

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Barriers to Employer Uptake of Anti-obesity Medication Coverage: Results from the OBSERVE Study von Gudzune, Kimberly, Kumar, Rekha, Kaplan, Lee, Sims, Tracy, Demauri, Mackie, Senglaub, Steven, Jauregui, Adam, Dunn, Julia, Ahmad, Nadia, Kan, Hong

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Experience and Perceptions of Anti-obesity Medications Among Persons With Obesity or Overweight von Kaplan, Lee, Kumar, Rekha, Ahmad, Nadia, Sims, Tracy, Kan, Hong, Mackie, Demauri, King-Concialdi, Kristen, Senglaub, Steven, Kahan, Scott

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Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study von Korn, Stephanie, Corren, Jonathan, Bednarczyk, Artur, Ponnarambil, Sandhia, Caveney, Scott, Almqvist, Gun, Simonsson, Linda, Lawson, Kaitlyn, Bowen, Karin, Colice, Gene, Hetzel, Jorge Lima, Antila, Martti Anton, Bezerra, Patricia Gomes de Matos, Lemiere, Catherine, Mitchell, Patrick, Chouinard, Guy, Cheema, Amarjit S, Yang, William Ho-Ching, Philteos, George, Bourdin, Arnaud, Taille, Camille, Leroyer, Christophe, Beurnier, Antoine, Garcia, Gilles, Girodet, Pierre-Olivier, Blanc, François-Xavier, Wanin, Stéphanie, Just, Jocelyne, Geßner, Christian, Buhl, Roland Otto, Kornmann, Marc Oliver, Linnhoff, Anneliese, Ludwig-Sengpiel, Andrea, Steffen, Heiner, Hoffmann, Martin, Kirschner, Joachim, Schmidt, Olaf, Wand, Ori, Izbicki, Gabriel, Berkman, Neville, Adir, Yochai, Rewerska, Barbara, Kurbacheva, Oksana, Mikhailov, Sergey L, Albanna, Amr, Bernhardi, David, Hoosen, Farzana, Naidoo, Visvakuren, Nell, Haylene, Padayachee, Trevenesan, Reddy, Jeevren, Petrick, Friedrich, Vawda, Zubar Fazal Ahmed, Park, Hae-Sim, Cho, You Sook, Lee, Byung Jae, Chang, Yoon-Seok, Lee, Sook Young, Yoon, HyoungKyu, Min, Kyung Hoon, Cho, Young Joo, Sheu, Chau-Chyun, Tu, Chih-Yen, Lee, Kang-Yun, Ediger, Dane, Kalkan, Ilkay Koca, Makieieva, Nataliia, Ostrovskyy, Mykola, Dytyatkovs'ka, Yevgeniya, Mostovoy, Yuriy Mykhaylovych, Lebed, Kyrylo, Mooring, Timothy, Thompson, Ernest, Chappel, Christopher M, Cole, Jeremy, Greenwald, Gary I, Jones, Conigliaro, Klein, Ryan Mitchell, Weinstein, Steven F, Windom, Hugh H, Kao, Neil L, Bhat, Saligrama, Aish, Bassil, Kerwin, Edward M, Delgado, John Palsted, Thompson, Charles A, Alpizar, Sady A, Vadgama, Sanjay Virgi, Zafar, Zahid, Lugogo, NJira, Jain, Neal, Sher, Lawrence D, Andrawis, Nabil S, Fuentes, David, Gonzalez, Erika G, Totszollosy Tarpay, Martha M, Tillinghast, Jeffrey P, Korenblat, Phillip E, Shenoy, Kartik, Que, Loretta

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Variation in Weight Loss Goals of U.S. Adults Meeting BMI Criteria for Anti-Obesity Pharmacotherapy von Kan, Hong, Gudzune, Kimberly, Kaplan, Lee, Kahan, Scott, Ard, Jamy, Poon, Jiat Ling, Mackie, Demauri, Jauregui, Adam, Senglaub, Steven, Sims, Tracy, Dunn, Julia

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The Conceptual Definition of Sarcopenia: Delphi Consensus from the Global Leadership Initiative in Sarcopenia (GLIS) von Kirk, Ben, Cawthon, Peggy M, Arai, Hidenori, Ávila-Funes, José A, Barazzoni, Rocco, Bhasin, Shalender, Binder, Ellen F, Bruyere, Olivier, Cederholm, Tommy, Chen, Liang-Kung, Cooper, Cyrus, Duque, Gustavo, Fielding, Roger A, Guralnik, Jack, Kiel, Douglas P, Landi, Francesco, Reginster, Jean-Yves, Sayer, Avan A, Visser, Marjolein, von Haehling, Stephan, Woo, Jean, Cruz-Jentoft, Alfonso J

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Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer von Drilon, Alexander, Camidge, D. Ross, Lin, Jessica J., Kim, Sang-We, Solomon, Benjamin J., Dziadziuszko, Rafal, Besse, Benjamin, Goto, Koichi, de Langen, Adrianus Johannes, Wolf, Jürgen, Lee, Ki Hyeong, Popat, Sanjay, Springfeld, Christoph, Nagasaka, Misako, Felip, Enriqueta, Yang, Nong, Velcheti, Vamsidhar, Lu, Shun, Kao, Steven, Dooms, Christophe, Krebs, Matthew G., Yao, Wenxiu, Beg, Muhammad Shaalan, Hu, Xiufeng, Moro-Sibilot, Denis, Cheema, Parneet, Stopatschinskaja, Shanna, Mehta, Minal, Trone, Denise, Graber, Armin, Sims, Gregory, Yuan, Yong, Cho, Byoung Chul

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Predicting Alzheimer’s disease progression using multi-modal deep learning approach von Lee, Garam, Nho, Kwangsik, Kang, Byungkon, Sohn, Kyung-Ah, Kim, Dokyoon

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