Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation von Winkler, I G, Pettit, A R, Raggatt, L J, Jacobsen, R N, Forristal, C E, Barbier, V, Nowlan, B, Cisterne, A, Bendall, L J, Sims, N A, Lévesque, J-P

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Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes von Gooi, J.H, Pompolo, S, Karsdal, M.A, Kulkarni, N.H, Kalajzic, I, McAhren, S.H.M, Han, B, Onyia, J.E, Ho, P.W.M, Gillespie, M.T, Walsh, N.C, Chia, L.Y, Quinn, J.M.W, Martin, T.J, Sims, N.A

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Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males von SIMS, N. A, DUPONT, S, KRUST, A, CLEMENT-LACROIX, P, MINET, D, RESCHE-RIGON, M, GAILLARD-KELLY, M, BARON, R

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Regulatory pathways revealing new approaches to the development of anabolic drugs for osteoporosis von Martin, T. J., Sims, N. A., Ng, K. W.

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Proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair von Georgy, S.R, Pagel, C.N, Ghasem-Zadeh, A, Zebaze, R.M.D, Pike, R.N, Sims, N.A, Mackie, E.J

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Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone von Calvi, L M, Sims, N A, Hunzelman, J L, Knight, M C, Giovannetti, A, Saxton, J M, Kronenberg, H M, Baron, R, Schipani, E

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Severe developmental bone phenotype in ClC-7 deficient mice von Neutzsky-Wulff, A.V., Sims, N.A., Supanchart, C., Kornak, U., Felsenberg, D., Poulton, I.J., Martin, T.J., Karsdal, M.A., Henriksen, K.

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Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis von Baron, R, Sabatakos, G, Sims, N. A, Chen, J, Aoki, K, Kelz, M. B, Amling, M, Bouali, Y, Mukhopadhyay, K, Ford, K, Nestler, E. J

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Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling von Liu, X., D'Cruz, A.A., Hansen, J., Croker, B.A., Lawlor, K.E., Sims, N.A., Wicks, I.P.

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Mechanisms Involved in Skeletal Anabolic Therapies von MARTIN, T.J., QUINN, J.M.W., GILLESPIE, M.T., NG, K.W., KARSDAL, M.A., SIMS, N.A.

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Disrupted type II collagenolysis impairs angiogenesis, delays endochondral ossification and initiates aberrant ossification in mouse limbs von Gauci, S.J., Golub, S.B., Tatarczuch, L., Lee, E., Chan, D., Walsh, N.C., Little, C.B., Stanton, H., Lokmic, Z., Sims, N.A., Mackie, E.J., Fosang, A.J.

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Biomechanical testing of the calcified metacarpal articular surface and its association with subchondral bone microstructure in Thoroughbred racehorses von Williamson, A. J., Sims, N. A., Thomas, C. D. L., Lee, P. V. S., Stevenson, M. A., Whitton, R. C.

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The Increased Bone Mass in ΔFosB Transgenic Mice Is Independent of Circulating Leptin Levels von Kveiborg, M, Chiusaroli, R, Sims, N. A, Wu, M, Sabatakos, G, Horne, W. C, Baron, R

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The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: increased resorption and osteopenia in me(v)/me(v) mutant mice von Aoki, K, Didomenico, E, Sims, N A, Mukhopadhyay, K, Neff, L, Houghton, A, Amling, M, Levy, J B, Horne, W C, Baron, R

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Estradiol treatment transiently increases trabecular bone volume in ovariectomized rats von Sims, N.A., Morris, H.A., Moore, R.J., Durbridge, T.C.

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Decreased c-Src Expression Enhances Osteoblast Differentiation and Bone Formation von Marzia, Marilena, Sims, Natalie A., Voit, Susanne, Migliaccio, Silvia, Taranta, Anna, Bernardini, Silvia, Faraggiana, Tullio, Yoneda, Toshiyuki, Mundy, Gregory R., Boyce, Brendan F., Baron, Roland, Teti, Anna

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Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5 von Sims, N A, Clément-Lacroix, P, Da Ponte, F, Bouali, Y, Binart, N, Moriggl, R, Goffin, V, Coschigano, K, Gaillard-Kelly, M, Kopchick, J, Baron, R, Kelly, P A

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Regulating ΔFosB expression in adult tet-off-ΔFosB transgenic mice alters bone formation and bone mass von SIMS, N. A, SABATAKOS, G, CHEN, J.-S, KELZ, M. B, NESTLER, E. J, BARON, R

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Increased formation and decreased resorption of bone in mice with elevated vitamin D receptor in mature cells of the osteoblastic lineage von Gardiner, Edith M., Baldock, Paul A., Thomas, Gethin P., Sims, Natalie A., Henderson, N. Kathryn, Hollis, Bruce, White, Christopher P., Sunn, Kathryn L., Morrison, Nigel A., Walsh, William R., Eisman, John A.

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Increased bone resorption precedes increased bone formation in the ovariectomized rat von Sims, N. A., Morris, H. A., Moore, R. J., Durbridge, T. C.

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