Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity von Towne, Jennifer E., Renshaw, Blair R., Douangpanya, Jason, Lipsky, Brian P., Shen, Min, Gabel, Christopher A., Sims, John E.

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IL-1RL2 and its ligands contribute to the cytokine network in psoriasis von Blumberg, Hal, Dinh, Huyen, Dean, Jr, Charles, Trueblood, Esther S, Bailey, Keith, Shows, Donna, Bhagavathula, Narasimharao, Aslam, Muhammad Nadeem, Varani, James, Towne, Jennifer E, Sims, John E

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Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation von Blumberg, Hal, Dinh, Huyen, Trueblood, Esther S, Pretorius, James, Kugler, David, Weng, Ning, Kanaly, Suzanne T, Towne, Jennifer E, Willis, Cynthia R, Kuechle, Melanie K, Sims, John E, Peschon, Jacques J

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The IL-1 family: regulators of immunity von Sims, John E, Smith, Dirk E

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SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling von Li, Xiaoxia, Wald, David, Qin, Jinzhong, Zhao, Zhendong, Qian, Youcun, Naramura, Mayumi, Tian, Liping, Towne, Jennifer, Sims, John E, Stark, George R

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A Central Nervous System-Restricted Isoform of the Interleukin-1 Receptor Accessory Protein Modulates Neuronal Responses to Interleukin-1 von Smith, Dirk E., Lipsky, Brian P., Russell, Chris, Ketchem, Randal R., Kirchner, Jacqueline, Hensley, Kelly, Huang, Yangyang, Friedman, Wilma J., Boissonneault, Vincent, Plante, Marie-Michèle, Rivest, Serge, Sims, John E.

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A novel mutation of IL1RN in the deficiency of interleukin‐1 receptor antagonist syndrome: Description of two unrelated cases from Brazil von Jesus, Adriana A., Osman, Mazen, Silva, Clovis A., Kim, Peter W., Pham, Tuyet‐Hang, Gadina, Massimo, Yang, Barbara, Bertola, Débora R., Carneiro‐Sampaio, Magda, Ferguson, Polly J., Renshaw, Blair R., Schooley, Ken, Brown, Michael, Al‐Dosari, Asma, Al‐Alami, Jamil, Sims, John E., Goldbach‐Mansky, Raphaela, El‐Shanti, Hatem

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Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages von Martin, Unja, Scholler, John, Gurgel, Jesse, Renshaw, Blair, Sims, John E, Gabel, Christopher A

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IL-36R ligands are potent regulators of dendritic and T cells von Vigne, Solenne, Palmer, Gaby, Lamacchia, Céline, Martin, Praxedis, Talabot-Ayer, Dominique, Rodriguez, Emiliana, Ronchi, Francesca, Sallusto, Federica, Dinh, Huyen, Sims, John E., Gabay, Cem

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Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis von Marrakchi, Slaheddine, Guigue, Philippe, Renshaw, Blair R, Puel, Anne, Pei, Xue-Yuan, Fraitag, Sylvie, Zribi, Jihen, Bal, Elodie, Cluzeau, Céline, Chrabieh, Maya, Towne, Jennifer E, Douangpanya, Jason, Pons, Christian, Mansour, Sourour, Serre, Valérie, Makni, Hafedh, Mahfoudh, Nadia, Fakhfakh, Faiza, Bodemer, Christine, Feingold, Josué, Hadj-Rabia, Smail, Favre, Michel, Genin, Emmanuelle, Sahbatou, Mourad, Munnich, Arnold, Casanova, Jean-Laurent, Sims, John E, Turki, Hamida, Bachelez, Hervé, Smahi, Asma

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Neuron-specific effects of interleukin-1β are mediated by a novel isoform of the IL-1 receptor accessory protein von Huang, Yangyang, Smith, Dirk E, Ibáñez-Sandoval, Osvaldo, Sims, John E, Friedman, Wilma J

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IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells von Vigne, Solenne, Palmer, Gaby, Martin, Praxedis, Lamacchia, Céline, Strebel, Deborah, Rodriguez, Emiliana, Olleros, Maria L., Vesin, Dominique, Garcia, Irene, Ronchi, Francesca, Sallusto, Federica, Sims, John E., Gabay, Cem

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The Soluble Form of IL-1 Receptor Accessory Protein Enhances the Ability of Soluble Type II IL-1 Receptor to Inhibit IL-1 Action von Smith, Dirk E., Hanna, Roberta, Della Friend, Moore, Heather, Chen, Hongbo, Farese, Ann M., MacVittie, Thomas J., Virca, G.Duke, Sims, John E.

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IL-1 and IL-18 receptors, and their extended family von Sims, John E

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Accessory to inflammation von Sims, John E

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction von O'Neill, Luke A. J, Fitzgerald, Katherine A, Palsson-McDermott, Eva M, Bowie, Andrew G, Jefferies, Caroline A, Mansell, Ashley S, Brady, Gareth, Brint, Elizabeth, Dunne, Aisling, Gray, Pearl, Harte, Mary T, McMurray, Diane, Smith, Dirk E, Sims, John E, Bird, Timothy A

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Essential pathogenic role of endogenous IL‐18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL‐18‐b... von Nicoletti, Ferdinando, Marco, Roberto Di, Papaccio, Gianpaolo, Conget, Ignacio, Gomis, Ramon, Bernardini, Renato, Sims, John E., Shoenfeld, Yehuda, Bendtzen, Klaus

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Novel protein therapeutic joint retention strategy based on collagen‐binding Avimers von Hulme, Joanne T., D'Souza, Warren N., McBride, Helen J., Yoon, Bo‐Rin Park, Willee, Angela M., Duguay, Amy, Thomas, Melissa, Fan, Bin, Dayao, Maria Rosalyn, Rottman, James B., Merriam, Kim, Xie, Jiansong, Smith, Richard, Alba, Benjamin M., Case, Ryan B., Dang, Khue, Montalvan, Anielka, Grinberg, Natalia, Sun, Hong, Black, Roy A., Gabel, Christopher A., Sims, John E., Moore, Kevin, Bakker, Alice, Li, Peng

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Four New Members Expand the Interleukin-1 Superfamily von Smith, Dirk E., Renshaw, Blair R., Ketchem, Randal R., Kubin, Marek, Garka, Kirsten E., Sims, John E.

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Purification, Cloning, and Characterization of Nek8, a Novel NIMA-related Kinase, and Its Candidate Substrate Bicd2 von Holland, Pamela M., Milne, Alison, Garka, Kirsten, Johnson, Richard S., Willis, Cynthia, Sims, John E., Rauch, Charles T., Bird, Timothy A., Virca, G. Duke

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