MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes von Abdul Rehman, Syed Arif, Kristariyanto, Yosua Adi, Choi, Soo-Youn, Nkosi, Pedro Junior, Weidlich, Simone, Labib, Karim, Hofmann, Kay, Kulathu, Yogesh

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Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability von Kwasna, Dominika, Abdul Rehman, Syed Arif, Natarajan, Jayaprakash, Matthews, Stephen, Madden, Ross, De Cesare, Virginia, Weidlich, Simone, Virdee, Satpal, Ahel, Ivan, Gibbs-Seymour, Ian, Kulathu, Yogesh

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Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms von Malik, Asad U, Karapetsas, Athanasios, Nirujogi, Raja S, Mathea, Sebastian, Chatterjee, Deep, Pal, Prosenjit, Lis, Pawel, Taylor, Matthew, Purlyte, Elena, Gourlay, Robert, Dorward, Mark, Weidlich, Simone, Toth, Rachel, Polinski, Nicole K, Knapp, Stefan, Tonelli, Francesca, Alessi, Dario R

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The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms von Fulcher, Luke J, Bozatzi, Polyxeni, Tachie-Menson, Theresa, Wu, Kevin Z L, Cummins, Timothy D, Bufton, Joshua C, Pinkas, Daniel M, Dunbar, Karen, Shrestha, Sabin, Wood, Nicola T, Weidlich, Simone, Macartney, Thomas J, Varghese, Joby, Gourlay, Robert, Campbell, David G, Dingwell, Kevin S, Smith, James C, Bullock, Alex N, Sapkota, Gopal P

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Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma von Cammareri, Patrizia, Rose, Aidan M., Vincent, David F., Wang, Jun, Nagano, Ai, Libertini, Silvana, Ridgway, Rachel A., Athineos, Dimitris, Coates, Philip J., McHugh, Angela, Pourreyron, Celine, Dayal, Jasbani H. S., Larsson, Jonas, Weidlich, Simone, Spender, Lindsay C., Sapkota, Gopal P., Purdie, Karin J., Proby, Charlotte M., Harwood, Catherine A., Leigh, Irene M., Clevers, Hans, Barker, Nick, Karlsson, Stefan, Pritchard, Catrin, Marais, Richard, Chelala, Claude, South, Andrew P., Sansom, Owen J., Inman, Gareth J.

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Proteasomal Degradation of Human CYP1B1: Effect of the Asn453Ser Polymorphism on the Post-Translational Regulation of CYP1B1 Expression von Bandiera, Silvio, Weidlich, Simone, Harth, Volker, Broede, Peter, Ko, Yun, Friedberg, Thomas

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USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling von Herhaus, Lina, Al-Salihi, Mazin A., Dingwell, Kevin S., Cummins, Timothy D., Wasmus, Lize, Vogt, Janis, Ewan, Richard, Bruce, David, Macartney, Thomas, Weidlich, Simone, Smith, James C., Sapkota, Gopal P.

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OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3 von Herhaus, Lina, Al-Salihi, Mazin, Macartney, Thomas, Weidlich, Simone, Sapkota, Gopal P.

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A single MIU motif of MINDY‐1 recognizes K48‐linked polyubiquitin chains von Kristariyanto, Yosua Adi, Abdul Rehman, Syed Arif, Weidlich, Simone, Knebel, Axel, Kulathu, Yogesh

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CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription von Aregger, Michael, Kaskar, Aneesa, Varshney, Dhaval, Fernandez-Sanchez, Maria Elena, Inesta-Vaquera, Francisco A., Weidlich, Simone, Cowling, Victoria H.

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Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM von Varshney, Dhaval, Petit, Alain-Pierre, Bueren-Calabuig, Juan A, Jansen, Chimed, Fletcher, Dan A, Peggie, Mark, Weidlich, Simone, Scullion, Paul, Pisliakov, Andrei V, Cowling, Victoria H

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Expansion of DUB functionality generated by alternative isoforms - USP35, a case study von Leznicki, Pawel, Natarajan, Jayaprakash, Bader, Gerd, Spevak, Walter, Schlattl, Andreas, Abdul Rehman, Syed Arif, Pathak, Deepika, Weidlich, Simone, Zoephel, Andreas, Bordone, Marie C, Barbosa-Morais, Nuno L, Boehmelt, Guido, Kulathu, Yogesh

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HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation von Zhao, Jin-Feng, Rodger, Catherine E, Allen, George F G, Weidlich, Simone, Ganley, Ian G

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A metabolic checkpoint for mitophagy von Rodger, Catherine E, Allen, George F.G., Weidlich, Simone, Macartney, Thomas, Ganley, Ian

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DHX15 regulates CMTR1-dependent gene expression and cell proliferation von Inesta-Vaquera, Francisco, Chaugule, Viduth K, Galloway, Alison, Chandler, Laurel, Rojas-Fernandez, Alejandro, Weidlich, Simone, Peggie, Mark, Cowling, Victoria H

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Expansion of DUB functionality generated by alternative isoforms - USP35, a case study von Leznicki, Pawel, Natarajan, Jayaprakash, Bader, Gerd, Spevak, Walter, Schlattl, Andreas, Rehman, Syed Arif Abdul, Pathak, Deepika, Weidlich, Simone, Zoephel, Andreas, Bordone, Marie C, Barbosa-Morais, Nuno L, Boehmelt, Guido, Kulathu, Yogesh

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HIF1a-dependent mitophagy facilitates cardiomyoblast differentiation von Jin-Feng Zhao, Catherine E. Rodger, George F. G. Allen, Simone Weidlich, Ian G. Ganley

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Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser 16 to trigger its nuclear localization von Herhaus, Lina, Perez-Oliva, Ana B., Cozza, Giorgio, Gourlay, Robert, Weidlich, Simone, Campbell, David G., Pinna, Lorenzo A., Sapkota, Gopal P.

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Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma von Cammareri, Patrizia, Rose, Aidan M, Vincent, David F, Wang, Jun, Nagano, Ai, Libertini, Silvana, Ridgway, Rachel A, Athineos, Dimitris, Coates, Philip J, McHugh, Angela, Pourreyron, Celine, Dayal, Jasbani H S, Larsson, Jonas, Weidlich, Simone, Spender, Lindsay C, Sapkota, Gopal P, Purdie, Karin J, Proby, Charlotte M, Harwood, Catherine A, Leigh, Irene M, Clevers, Hans, Barker, Nick, Karlsson, Stefan, Pritchard, Catrin, Marais, Richard, Chelala, Claude, South, Andrew P, Sansom, Owen J, Inman, Gareth J

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Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization von Herhaus, Lina, Perez-Oliva, Ana B, Cozza, Giorgio, Gourlay, Robert, Weidlich, Simone, Campbell, David G, Pinna, Lorenzo A, Sapkota, Gopal P

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