Drugging MYCN through an Allosteric Transition in Aurora Kinase A von Gustafson, William Clay, Meyerowitz, Justin Gabriel, Nekritz, Erin A., Chen, Justin, Benes, Cyril, Charron, Elise, Simonds, Erin F., Seeger, Robert, Matthay, Katherine K., Hertz, Nicholas T., Eilers, Martin, Shokat, Kevan M., Weiss, William A.

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Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development von Bendall, Sean C., Davis, Kara L., Amir, El-ad David, Tadmor, Michelle D., Simonds, Erin F., Chen, Tiffany J., Shenfeld, Daniel K., Nolan, Garry P., Pe’er, Dana

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Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis von Levine, Jacob H., Simonds, Erin F., Bendall, Sean C., Davis, Kara L., Amir, El-ad D., Tadmor, Michelle D., Litvin, Oren, Fienberg, Harris G., Jager, Astraea, Zunder, Eli R., Finck, Rachel, Gedman, Amanda L., Radtke, Ina, Downing, James R., Pe’er, Dana, Nolan, Garry P.

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A Universal Live Cell Barcoding-Platform for Multiplexed Human Single Cell Analysis von Hartmann, Felix J., Simonds, Erin F., Bendall, Sean C.

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viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia von Amir, El-ad David, Davis, Kara L, Tadmor, Michelle D, Simonds, Erin F, Levine, Jacob H, Bendall, Sean C, Shenfeld, Daniel K, Krishnaswamy, Smita, Nolan, Garry P, Pe'er, Dana

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Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum von Bendall, Sean C., Simonds, Erin F., Qiu, Peng, Amir, El-ad D., Krutzik, Peter O., Finck, Rachel, Bruggner, Robert V., Melamed, Rachel, Trejo, Angelica, Ornatsky, Olga I., Balderas, Robert S., Plevritis, Sylvia K., Sachs, Karen, Pe'er, Dana, Tanner, Scott D., Nolan, Garry P.

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Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators von Bodenmiller, Bernd, Zunder, Eli R, Finck, Rachel, Chen, Tiffany J, Savig, Erica S, Bruggner, Robert V, Simonds, Erin F, Bendall, Sean C, Sachs, Karen, Krutzik, Peter O, Nolan, Garry P

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A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma von Fan, QiWen, Aksoy, Ozlem, Wong, Robyn A., Ilkhanizadeh, Shirin, Novotny, Chris J., Gustafson, William C., Truong, Albert Yi-Que, Cayanan, Geraldine, Simonds, Erin F., Haas-Kogan, Daphne, Phillips, Joanna J., Nicolaides, Theodore, Okaniwa, Masanori, Shokat, Kevan M., Weiss, William A.

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Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse von Good, Zinaida, Sarno, Jolanda, Jager, Astraea, Samusik, Nikolay, Aghaeepour, Nima, Simonds, Erin F, White, Leah, Lacayo, Norman J, Fantl, Wendy J, Fazio, Grazia, Gaipa, Giuseppe, Biondi, Andrea, Tibshirani, Robert, Bendall, Sean C, Nolan, Garry P, Davis, Kara L

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Pediatric high-grade glioma: biologically and clinically in need of new thinking von Jones, Chris, Karajannis, Matthias A, Jones, David T W, Kieran, Mark W, Monje, Michelle, Baker, Suzanne J, Becher, Oren J, Cho, Yoon-Jae, Gupta, Nalin, Hawkins, Cynthia, Hargrave, Darren, Haas-Kogan, Daphne A, Jabado, Nada, Li, Xiao-Nan, Mueller, Sabine, Nicolaides, Theo, Packer, Roger J, Persson, Anders I, Phillips, Joanna J, Simonds, Erin F, Stafford, James M, Tang, Yujie, Pfister, Stefan M, Weiss, William A

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Normalization of mass cytometry data with bead standards von Finck, Rachel, Simonds, Erin F., Jager, Astraea, Krishnaswamy, Smita, Sachs, Karen, Fantl, Wendy, Pe'er, Dana, Nolan, Garry P., Bendall, Sean C.

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Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE von Qiu, Peng, Simonds, Erin F, Bendall, Sean C, Gibbs, Kenneth D, Bruggner, Robert V, Linderman, Michael D, Sachs, Karen, Nolan, Garry P, Plevritis, Sylvia K

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Single-cell RNA-Seq of follicular lymphoma reveals malignant B-cell types and coexpression of T-cell immune checkpoints von Andor, Noemi, Simonds, Erin F., Czerwinski, Debra K., Chen, Jiamin, Grimes, Susan M., Wood-Bouwens, Christina, Zheng, Grace X.Y., Kubit, Matthew A., Greer, Stephanie, Weiss, William A., Levy, Ronald, Ji, Hanlee P.

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A platinum‐based covalent viability reagent for single‐cell mass cytometry von Fienberg, Harris G., Simonds, Erin F., Fantl, Wendy J., Nolan, Garry P., Bodenmiller, Bernd

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Single-Cell Profiling Identifies Aberrant STAT5 Activation in Myeloid Malignancies with Specific Clinical and Biologic Correlates von Kotecha, Nikesh, Flores, Nikki J., Irish, Jonathan M., Simonds, Erin F., Sakai, Debbie S., Archambeault, Sophie, Diaz-Flores, Ernesto, Coram, Marc, Shannon, Kevin M., Nolan, Garry P., Loh, Mignon L.

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Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms von Oh, Stephen T., Simonds, Erin F., Jones, Carol, Hale, Matthew B., Goltsev, Yury, Gibbs, Kenneth D., Merker, Jason D., Zehnder, James L., Nolan, Garry P., Gotlib, Jason

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Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma von Simonds, Erin F, Lu, Edbert D, Badillo, Oscar, Karimi, Shokoufeh, Liu, Eric V, Tamaki, Whitney, Rancan, Chiara, Downey, Kira M, Stultz, Jacob, Sinha, Meenal, McHenry, Lauren K, Nasholm, Nicole M, Chuntova, Pavlina, Sundström, Anders, Genoud, Vassilis, Shahani, Shilpa A, Wang, Leo D, Brown, Christine E, Walker, Paul R, Swartling, Fredrik J, Fong, Lawrence, Okada, Hideho, Weiss, William A, Hellström, Mats

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Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis von Hartmann, Felix J., Simonds, Erin F., Vivanco, Nora, Bruce, Trevor, Borges, Luciene, Nolan, Garry P., Spitzer, Matthew H., Bendall, Sean C.

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Switchable assembly and function of antibody complexes in vivo using a small molecule von Martinko, Alexander J., Simonds, Erin F., Prasad, Suchitra, Ponce, Alberto, Bracken, Colton, Wei, Junnian, Wang, Yung-Hua, Chow, Tiffany-Lynn, Huang, Zhong, Evans, Michael J., Wells, James A., Hill, Zachary B.

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GateFinder: projection-based gating strategy optimization for flow and mass cytometry von Aghaeepour, Nima, Simonds, Erin F, Knapp, David J H F, Bruggner, Robert V, Sachs, Karen, Culos, Anthony, Gherardini, Pier Federico, Samusik, Nikolay, Fragiadakis, Gabriela K, Bendall, Sean C, Gaudilliere, Brice, Angst, Martin S, Eaves, Connie J, Weiss, William A, Fantl, Wendy J, Nolan, Garry P

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