Sonic hedgehog: restricted expression and limb dysmorphologies von Hill, Robert E., Heaney, Simon J. H., Lettice, Laura A.

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A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly von Lettice, Laura A., Heaney, Simon J.H., Purdie, Lorna A., Li, Li, de Beer, Philippe, Oostra, Ben A., Goode, Debbie, Elgar, Greg, Hill, Robert E., de Graaff, Esther

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Disruption of a Long-Range Cis-Acting Regulator for Shh Causes Preaxial Polydactyly von Lettice, Laura A., Horikoshi, Taizo, Simon J. H. Heaney, van Baren, Marijke J., van der Linde, Herma C., Breedveld, Guido J., Joosse, Marijke, Akarsu, Nurten, Oostra, Ben A., Endo, Naoto, Shibata, Minoru, Suzuki, Mikio, Takahashi, Eiichi, Shinka, Toshikatsu, Nakahori, Yutaka, Ayusawa, Dai, Nakabayashi, Kazuhiko, Scherer, Stephen W., Heutink, Peter, Hill, Robert E., Noji, Sumihare

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Sasquatch mouse: an enhanced limb von Heaney, Simon J. H

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The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease von Adeloye, Davies, Elneima, Omer, Daines, Luke, Poinasamy, Krisnah, Quint, Jennifer K, Walker, Samantha, Brightling, Chris E, Siddiqui, Salman, Hurst, John R, Chalmers, James D, Pfeffer, Paul E, Novotny, Petr, Drake, Thomas M, Heaney, Liam G, Rudan, Igor, Sheikh, Aziz, De Soyza, Anthony, Adeloye, Davies, Elneima, Omer, Daines, Luke, Poinasamy, Krisnah, Quint, Jennifer K, Walker, Samantha, Brightling, Chris E, Siddiqui, Salman, Hurst, John R, Chalmers, James D, Pfeffer, Paul E, Novotny, Petr, Drake, Thomas M, Abdollahi, Mohammad, Agarwal, Dhiraj, Al-Lehebi, Riyad, Barnes, Peter J, Bayry, Jagadeesh, Bonay, Marcel, Bont, Louis J, Bourdin, Arnaud, Brown, Thomas, Caramori, Gaetano, Chan, Amy Hai Yan, Dockrell, David H, Doe, Simon, Duckers, Jamie, D'Urzo, Anthony, Ekström, Magnus, Esteban, Cristóbal, Greene, Catherine M, Gupta, Atul, Ingram, Jennifer L, Khoo, Ee Ming, Ko, Fanny Wai San, Koppelman, Gerard H, Lipworth, Brian J, Lisspers, Karin, Loebinger, Michael, Lopez-Campos, Jose Luis, Maddocks, Matthew, Mannino, David, Martinez-Garcia, Miguel A, Mcnamara, Renae, Miravitlles, Marc, Ndarukwa, Pisirai, Pooler, Alison, Rhee, Chin Kook, Schwarz, Peter, Shaw, Dominick, Steiner, Michael, Tai, Andrew, Ulrik, Charlotte Suppli, Walker, Paul, Williams, Michelle C, Heaney, Liam G, Rudan, Igor, Sheikh, Aziz, De Soyza, Anthony

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Characterisation of patients with severe asthma in the UK Severe Asthma Registry in the biologic era von Jackson, David J, Busby, John, Pfeffer, Paul E, Menzies-Gow, Andrew, Brown, Thomas, Gore, Robin, Doherty, Martin, Mansur, Adel H, Message, Simon, Niven, Robert, Patel, Mitesh, Heaney, Liam G, Dilworth, Paul, Vyas, Aashish, Chadhuri, Rekha, Subramnian, Deepak, Dennison, Paddy

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Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma von Couillard, Simon, Shrimanker, Rahul, Chaudhuri, Rekha, Mansur, Adel H., McGarvey, Lorcan P., Heaney, Liam G., Fowler, Stephen J., Bradding, Peter, Pavord, Ian D., Hinks, Timothy S. C.

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Phenotypic and functional translation of IL33 genetics in asthma von Ketelaar, Maria E., Portelli, Michael A., Dijk, F. Nicole, Shrine, Nick, Faiz, Alen, Vermeulen, Cornelis J., Xu, Cheng J., Hankinson, Jenny, Bhaker, Sangita, Henry, Amanda P., Billington, Charlote K., Shaw, Dominick E., Johnson, Simon R., Benest, Andrew V., Pang, Vincent, Bates, David O., Pogson, Z.E.K., Fogarty, Andrew, McKeever, Tricia M., Singapuri, Amisha, Heaney, Liam G., Mansur, Adel H., Chaudhuri, Rekha, Thomson, Neil C., Holloway, John W., Lockett, Gabrielle A., Howarth, Peter H., Niven, Robert, Simpson, Angela, Tobin, Martin D., Hall, Ian P., Wain, Louise V., Blakey, John D., Brightling, Christopher E., Obeidat, Ma'en, Sin, Don D., Nickle, David C., Bossé, Yohan, Vonk, Judith M., van den Berge, Maarten, Koppelman, Gerard H., Sayers, Ian, Nawijn, Martijn C.

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Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma von Khalfaoui, Latifa, Symon, Fiona A., Couillard, Simon, Hargadon, Beverley, Chaudhuri, Rekha, Bicknell, Steve, Mansur, Adel H., Shrimanker, Rahul, Hinks, Timothy S. C., Pavord, Ian D., Fowler, Stephen J., Brown, Vanessa, McGarvey, Lorcan P., Heaney, Liam G., Austin, Cary D., Howarth, Peter H., Arron, Joseph R., Choy, David F., Bradding, Peter

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7 von Curran, Martin D., Roy, Sunando, Shaaban, Sharif, de Cesare, Mariateresa, Stark, Richard, Palmer, Steve, Jeffries, Aaron R., da Silva Filipe, Ana, Davis, Thomas, Collins, Jennifer, Williams, Thomas, Haldenby, Sam T., Cook, Kate, Davies, Robert, Kay, Sally, Poplawski, Radoslaw, Reynolds, Nicola, Moll, Robin J., Thornton, Alicia, Gatica-Wilcox, Bree, Louka, Stavroula F., Kraemer, Moritz U.G., Freeman, Timothy M., Abudahab, Khalil, Menegazzo, Mirko, Mason, Jenifer, Holmes, Alison, Curran, Tanya, Mookerjee, Siddharth, Munn, Robert, Davies, Alisha, Smith, Nikki, Cormie, Claire, Lo, Stephanie, Auckland, Cressida, Mollett, Guy, Harper, Katherine L., Bonner, Stephen, Padgett, Debra, Burton-Fanning, Shirelle, Bedford, Luke, Coupland, Lindsay, Wright, Victoria, Ball, Jonathan, Boswell, Tim, Duckworth, Nichola, Williams, Rebecca, Cogger, Benjamin J., Farr, Ben W., Thurston, Scott A.J., Bronner, Iraad F., Aigrain, Louise, Gallagher, Michael D., Miah, Shahjahan, Ramsay, Mary, Schaefer, Ulf, Manesis, Nikos, Allara, Elias, Nichols, Jenna, Vamos, Edith E., Hughes, Margaret, Wilson, Harry D., Wilson, Rebekah E., Thompson, Thomas, O’Brien, Sarah, Rudder, Steven, McCluggage, Kathryn, Bonfield, James, Liddle, Jennifier, Rowe, Will, Bevan, Paul, Clark, Richard, Cutts, Tim, Densem, Aiden, Dodd, David, Griffiths, Coline, Kay, Keely, Lensing, Stefanie, Lewis-Wade, Amanah, Mamun, Irfan, Martin, Matt, McClintock, Jo, Nathwani, Claire, Nicholson, Jon, Patel, Gaurang, Petersen, Arabella, Reynolds, Joe, Rudd, Luke, Sadri, Ramin, Sizer, Dale, Soria, Carmen Diaz, Sousa, Catarina, Squares, Janet, Stickland, Tim, Still, Ian, Symons, Edward, Uphill, James, Van, Philip Jansen, Voak, Paul, Corti, Davide

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Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study von Elneima, Omer, McAuley, Hamish J C, Leavy, Olivia C, Chalmers, James D, Horsley, Alex, Ho, Ling-Pei, Marks, Michael, Poinasamy, Krisnah, Raman, Betty, Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Harris, Victoria C, Houchen-Wolloff, Linzy, Saunders, Ruth M, Greening, Neil J, Richardson, Matthew, Quint, Jennifer K, Briggs, Andrew, Docherty, Annemarie B, Kerr, Steven, Harrison, Ewen M, Lone, Nazir I, Thorpe, Mathew, Heaney, Liam G, Lewis, Keir E, Aul, Raminder, Beirne, Paul, Bolton, Charlotte E, Brown, Jeremy S, Choudhury, Gourab, Bakerly, Nawar Diar, Easom, Nicholas, Echevarria, Carlos, Fuld, Jonathan, Hart, Nick, Hurst, John R, Jones, Mark G, Parekh, Dhruv, Pfeffer, Paul, Rahman, Najib M, Rowland-Jones, Sarah L, Thompson, Aa Roger, Jolley, Caroline, Shah, Ajay M, Wootton, Dan G, Chalder, Trudie, Davies, Melanie J, De Soyza, Anthony, Geddes, John R, Greenhalf, William, Heller, Simon, Howard, Luke S, Jacob, Joseph, Jenkins, R Gisli, Lord, Janet M, Man, William D-C, McCann, Gerry P, Neubauer, Stefan, Openshaw, Peter Jm, Porter, Joanna C, Rowland, Matthew J, Scott, Janet T, Semple, Malcolm G, Singh, Sally J, Thomas, David C, Toshner, Mark, Smith, Nikki, Sheikh, Aziz, Brightling, Christopher E, Wain, Louise V, Evans, Rachael A

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De novo variants in FRYL are associated with developmental delay, intellectual disability, and dysmorphic features von Pan, Xueyang, Tao, Alice M., Lu, Shenzhao, Ma, Mengqi, Hannan, Shabab B., Slaugh, Rachel, Drewes Williams, Sarah, O'Grady, Lauren, Kanca, Oguz, Person, Richard, Carter, Melissa T., Platzer, Konrad, Schnabel, Franziska, Abou Jamra, Rami, Roberts, Amy E., Newburger, Jane W., Revah-Politi, Anya, Granadillo, Jorge L., Stegmann, Alexander P.A., Sinnema, Margje, Accogli, Andrea, Salpietro, Vincenzo, Capra, Valeria, Ghaloul-Gonzalez, Lina, Brueckner, Martina, Simon, Marleen E.H., Sweetser, David A., Glinton, Kevin E., Kirk, Susan E., Burrage, Lindsay C., Heaney, Jason D., Kim, Seon-Young, Lanza, Denise G., Liu, Zhandong, Mao, Dongxue, Milosavljevic, Aleksander, Nagamani, Sandesh C.S., Posey, Jennifer E., Ramamurthy, Uma, Ramanathan, Vivek, Rogers, Jeffrey, Rosenfeld, Jill A., Roth, Matthew, Zahedi Darshoori, Ramin, Wangler, Michael F., Yamamoto, Shinya, Chung, Wendy K., Bellen, Hugo J.

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The impact of the first COVID-19 surge on severe asthma patients in the UK. Which is worse: the virus or the lockdown? von Smith, Steven J., Busby, John, Heaney, Liam G., Pfeffer, Paul E., Jackson, David J., Yang, Freda, Fowler, Stephen J., Menzies-Gow, Andrew, Idris, Elfatih, Brown, Thomas, Gore, Robin, Faruqi, Shoaib, Dennison, Paddy, Dodd, James W., Doe, Simon, Mansur, Adel H., Priyadarshi, Radhika, Holmes, Joshua, Hearn, Andrew, Al-Aqqad, Hamsa, Loewenthal, Lola, Cooper, Angela, Fox, Lauren, Selvan, Mayurun, Crooks, Michael G., Thompson, Alison, Higbee, Daniel, Fawdon, Michelle, Nathwani, Vishal, Holmes, LeanneJo, Chaudhuri, Rekha

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Ethnic Differences in Severe Asthma Clinical Care and Outcomes: An Analysis of United Kingdom Primary and Specialist Care von Busby, John, Heaney, Liam G., Brown, Thomas, Chaudhuri, Rekha, Dennison, Paddy, Gore, Robin, Jackson, David J., Mansur, Adel H., Menzies-Gow, Andrew, Message, Simon, Niven, Rob, Patel, Mitesh, Price, David, Siddiqui, Salman, Stone, Robert, Pfeffer, Paul E.

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Application of SARS-CoV-2 Serology to Address Public Health Priorities von Sherman, Amy C., Smith, Teresa, Zhu, Yerun, Taibl, Kaitlin, Howard-Anderson, Jessica, Landay, Taylor, Pisanic, Nora, Kleinhenz, Jennifer, Simon, Trevor W., Espinoza, Daniel, Edupuganti, Neena, Hammond, Skyler, Rouphael, Nadine, Shen, Huifeng, Fairley, Jessica K., Edupuganti, Srilatha, Cardona-Ospina, Jaime A., Rodriguez-Morales, Alfonso J., Premkumar, Lakshmanane, Wrammert, Jens, Tarleton, Rick, Fridkin, Scott, Heaney, Christopher D., Scherer, Erin M., Collins, Matthew H.

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Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium von Portelli, Michael A., Dijk, F. Nicole, Ketelaar, Maria E., Shrine, Nick, Hankinson, Jenny, Bhaker, Sangita, Grotenboer, Neomi S., Obeidat, Ma'en, Henry, Amanda P., Billington, Charlotte K., Shaw, Dominick, Johnson, Simon R., Pogson, Zara E. K., Fogarty, Andrew, McKeever, Tricia M., Nickle, David C., Bosse, Yohan, van den Berge, Maarten, Faiz, Alen, Brouwer, Sharon, Vonk, Judith M., de Vos, Paul, Brandsma, Corry-Anke, Vermeulen, Cornelis J., Singapuri, Amisha, Heaney, Liam G., Mansur, Adel H., Chaudhuri, Rekha, Thomson, Neil C., Holloway, John W., Lockett, Gabrielle A., Howarth, Peter H., Niven, Robert, Simpson, Angela, Blakey, John D., Tobin, Martin D., Postma, Dirkje S., Hall, Ian P., Wain, Louise, Nawijn, Martijn C., Brightling, Christopher E., Koppelman, Gerard H., Sayers, Ian

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Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density von Swan, AL, Schuett, C, Rozman, J, Moreno, MDMM, Brandmaier, S, Simon, M, Leuchtenberger, S, Griffiths, M, Brommage, R, Keskivali-Bond, P, Grallert, H, Werner, T, Teperino, R, Becker, L, Miller, G, Moshiri, A, Seavitt, JR, Cissell, DD, Meehan, TF, Acar, EF, Lelliott, CJ, Flenniken, AM, Champy, M-F, Sorg, T, Ayadi, A, Braun, RE, Cater, H, Dickinson, ME, Flicek, P, Gallegos, J, Ghirardello, EJ, Heaney, JD, Jacquot, S, Lally, C, Logan, JG, Teboul, L, Mason, J, Spielmann, N, McKerlie, C, Murray, SA, Nutter, LMJ, Odfalk, KF, Parkinson, H, Prochazka, J, Reynolds, CL, Selloum, M, Spoutil, F, Svenson, KL, Vales, TS, Wells, SE, White, JK, Sedlacek, R, Wurst, W, Lloyd, KKC, Croucher, P, Fuchs, H, Williams, GR, Bassett, D, Gailus-Durner, V, Herault, Y, Mallon, A-M, Brown, SDM, Mayer-Kuckuk, P, De Angelis, MH

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Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes von McHugh, M.P., Rambaut, Andrew, Snell, Luke B., Jackson, David K., Moore, Catherine, Jackson, Leigh M., Aanensen, David M., Barrett, Jeffrey C., Bashton, Matthew, Wang, Dennis, Thomas, Claire, Simpson, David A., Paterson, Steve, Pybus, Oliver G., Taylor, Joshua F., Crown, Matthew R., Monahan, Irene M., Silviera, Siona, Harvey, William T., O'Toole, Áine, Kitchman, Katie, Dervisevic, Samir, Barrow, Magdalena, Xu-McCrae, Li, Cox, Alison, Withell, Karen T., Denton-Smith, Rebecca, Sloan, Tim J., Pymont, Hannah M., Crudgington, Dorian, Iturriza-Gomara, Miren, Rooke, Stefan, Yebra, Gonzalo, Blane, Beth, Green, Angie, Kay, Sally, Reynolds, Nicola, Hollis, Amy, Yew, Wen C., Hey, Jessica, Jones, Hannah, Hornsby, Hailey R., Pohare, Manoj, Boyd, Olivia, Jackson, Chris, Vattipally, Sreenu, de Oliveira Martins, Leonardo, Jackson, Ben, Medd, Nathan, Smith, Ken, Guest, Martyn, Kitchen, Christine, Churcher, Carol M., Delgado Callico, Laia, Judges, Sarah, Bolt, Frances, De Lacy, Elen, Foulser, Luke, Boswell, Tim, Howson-Wells, Hannah C., Khakh, Manjinder, Lister, Michelle M., Helmer, Thomas, Hughes, Warwick, Lee, Jack CD, Shah, Divya, Ohemeng-Kumi, Natasha, Sluga, Graciela, Ahmad, Shazaad SY, Barton, Edward, Scott, Garren, Johnson, Kate, Lawton, Andrew I., Ashfield, Paula, Best, Angus, Crawford, Liam, Ensell, Leah, Easton, Lisa J., Nicodemi, Roberto, Beggs, Andrew, Dias, Joana, Park, Emily J., Francois, Sarah, Ragonnet-Cronin, Manon, Nichols, Jenna, Nomikou, Kyriaki, Tsatsani, Ioulia, Hubb, Jonathan, Manesis, Nikos, Aydin, Alp, Foster-Nyarko, Ebenezer, Prosolek, Sophie J., Mariappan, Arun, Bayzid, Nadua, Cotic, Marius, Michelsen, Michelle L., Eccles, Richard, Gemmell, Matthew, Gregory, Richard, Bronner, Iraad F.

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SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2 von Eales, Oliver, Page, Andrew J, de Oliveira Martins, Leonardo, Wang, Haowei, Bodinier, Barbara, Haw, David, Jonnerby, Jakob, Atchison, Christina, Ashby, Deborah, Barclay, Wendy, Taylor, Graham, Cooke, Graham, Ward, Helen, Darzi, Ara, Riley, Steven, Chadeau-Hyam, Marc, Donnelly, Christl A, Elliott, Paul

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Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps... von Lawton, J., Kirkham, J., Rankin, D., White, D. A., Elliott, J., Jaap, A., Smithson, W. H., Heller, S.

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