VPS35 and the mitochondria: Connecting the dots in Parkinson's disease pathophysiology von Cutillo, Gianni, Simon, David K., Eleuteri, Simona

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Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases von Espay, Alberto J, Vizcarra, Joaquin A, Marsili, Luca, Lang, Anthony E, Simon, David K, Merola, Aristide, Josephs, Keith A, Fasano, Alfonso, Morgante, Francesca, Savica, Rodolfo, Greenamyre, J Timothy, Cambi, Franca, Yamasaki, Tritia R, Tanner, Caroline M, Gan-Or, Ziv, Litvan, Irene, Mata, Ignacio F, Zabetian, Cyrus P, Brundin, Patrik, Fernandez, Hubert H, Standaert, David G, Kauffman, Marcelo A, Schwarzschild, Michael A, Sardi, S Pablo, Sherer, Todd, Perry, George, Leverenz, James B

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Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators von St-Pierre, Julie, Drori, Stavit, Uldry, Marc, Silvaggi, Jessica M., Rhee, James, Jäger, Sibylle, Handschin, Christoph, Zheng, Kangni, Lin, Jiandie, Yang, Wenli, Simon, David K., Bachoo, Robert, Spiegelman, Bruce M.

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Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration von Quansah, Emmanuel, Peelaerts, Wouter, Langston, J William, Simon, David K, Colca, Jerry, Brundin, Patrik

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Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2 von Pankratz, Nathan, Beecham, Gary W., DeStefano, Anita L., Dawson, Ted M., Doheny, Kimberly F., Factor, Stewart A., Hamza, Taye H., Hung, Albert Y., Hyman, Bradley T., Ivinson, Adrian J., Krainc, Dmitri, Latourelle, Jeanne C., Clark, Lorraine N., Marder, Karen, Martin, Eden R., Mayeux, Richard, Ross, Owen A., Scherzer, Clemens R., Simon, David K., Tanner, Caroline, Vance, Jeffery M., Wszolek, Zbigniew K., Zabetian, Cyrus P., Myers, Richard H., Payami, Haydeh, Scott, William K., Foroud, Tatiana

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Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease mouse model von Fang, Tracy-Shi Zhang, Sun, Yu, Pearce, Andrew C., Eleuteri, Simona, Kemp, Mark, Luckhurst, Christopher A., Williams, Rachel, Mills, Ross, Almond, Sarah, Burzynski, Laura, Márkus, Nóra M., Lelliott, Christopher J., Karp, Natasha A., Adams, David J., Jackson, Stephen P., Zhao, Jin-Feng, Ganley, Ian G., Thompson, Paul W., Balmus, Gabriel, Simon, David K.

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Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice von Clark, Joanne, Clore, Elizabeth L, Zheng, Kangni, Adame, Anthony, Masliah, Eliezer, Simon, David K

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Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease von Clark, Joanne, Simon, David K

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An inverse-Warburg effect and the origin of Alzheimer’s disease von Demetrius, Lloyd A., Simon, David K.

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Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf von Clark, Joanne, Silvaggi, Jessica M, Kiselak, Tomas, Zheng, Kangni, Clore, Elizabeth L, Dai, Ying, Bass, Caroline E, Simon, David K

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Altered muscle electrical tissue properties in a mouse model of premature aging von Clark‐Matott, Joanne, Nagy, Janice A., Sanchez, Benjamin, Taylor, Rebecca, Riveros, Daniela, Abraham, Neeta A., Simon, David K., Rutkove, Seward B.

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Somatic mitochondrial DNA mutations in early parkinson and incidental lewy body disease von Lin, Michael T., Cantuti-Castelvetri, Ippolita, Zheng, Kangni, Jackson, Katie E., Tan, Yong B., Arzberger, Thomas, Lees, Andrew J., Betensky, Rebecca A., Beal, M. Flint, Simon, David K.

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Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease von Clark, Joanne, Reddy, Sonika, Zheng, Kangni, Betensky, Rebecca A, Simon, David K

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Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival von Lee, Junghee, Kim, Chun-Hyung, Simon, David K., Aminova, Lyaylya R., Andreyev, Alexander Y., Kushnareva, Yulia E., Murphy, Anne N., Lonze, Bonnie E., Kim, Kwang-Soo, Ginty, David D., Ferrante, Robert J., Ryu, Hoon, Ratan, Rajiv R.

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Efficacy of Deep Brain Stimulation in a Patient with Genetically Confirmed Chorea-Acanthocytosis von Richard, Alby, Hsu, Joey, Baum, Patricia, Alterman, Ron, Simon, David K.

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Trial of Cinpanemab in Early Parkinson’s Disease von Lang, Anthony E., Siderowf, Andrew D., Macklin, Eric A., Poewe, Werner, Brooks, David J., Fernandez, Hubert H., Rascol, Olivier, Giladi, Nir, Stocchi, Fabrizio, Tanner, Caroline M., Postuma, Ronald B., Simon, David K., Tolosa, Eduardo, Mollenhauer, Brit, Cedarbaum, Jesse M., Fraser, Kyle, Xiao, James, Evans, Karleyton C., Graham, Danielle L., Sapir, Inbal, Inra, Jennifer, Hutchison, R. Matthew, Yang, Minhua, Fox, Tara, Budd Haeberlein, Samantha, Dam, Tien

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Dystonia von Tarsy, Daniel, Simon, David K

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Associations between exercise classes and self-reported exercise by people with Parkinson’s disease at Parkinson’s foundation centers of excellence von Nettnin, Ella, Burrows, Stephanie, Miao, Guanhong, Wu, Samuel S., Simon, David K., Rafferty, Miriam R.

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No sex differences in use of dopaminergic medication in early Parkinson disease in the US and Canada - baseline findings of a multicenter trial von Umeh, Chizoba C, Pérez, Adriana, Augustine, Erika F, Dhall, Rohit, Dewey, Jr, Richard B, Mari, Zoltan, Simon, David K, Wills, Anne-Marie A, Christine, Chadwick W, Schneider, Jay S, Suchowersky, Oksana

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CURRENT CONCEPTS: Dystonia von Tarsy, Daniel, Simon, David K

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