Conformational Recognition of an Intrinsically Disordered Protein von Krieger, James M., Fusco, Giuliana, Lewitzky, Marc, Simister, Philip C., Marchant, Jan, Camilloni, Carlo, Feller, Stephan M., De Simone, Alfonso

Volltext

An Objective Assessment of Conformational Variability in Complexes of Hepatitis C Virus Polymerase with Non-Nucleoside Inhibitors von Caillet-Saguy, Célia, Simister, Philip C., Bressanelli, Stéphane

Volltext

GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development von Paster, Wolfgang, Brockmeyer, Claudia, Fu, Guo, Simister, Philip C, de Wet, Ben, Martinez-Riaño, Ana, Hoerter, John A H, Feller, Stephan M, Wülfing, Christoph, Gascoigne, Nicholas R J, Acuto, Oreste

Volltext

A THEMIS:SHP1 complex promotes T-cell survival von Paster, Wolfgang, Bruger, Annika M, Katsch, Kristin, Grégoire, Claude, Roncagalli, Romain, Fu, Guo, Gascoigne, Nicholas RJ, Nika, Konstantina, Cohnen, Andre, Feller, Stephan M, Simister, Philip C, Molder, Kelly C, Cordoba, Shaun-Paul, Dushek, Omer, Malissen, Bernard, Acuto, Oreste

Volltext

Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide von Sato, Seiichi, Zhao, Yingshe, Imai, Misa, Simister, Philip C, Feller, Stephan M, Trackman, Philip C, Kirsch, Kathrin H, Sonenshein, Gail E

Volltext

Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy von Simister, Philip C, Border, Ellen C, Vieira, João F, Pumphrey, Nicholas J

Volltext

A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes von SCHMITT, Melanie, SCRIMA, Nathalie, BRESSANELLI, Stéphane, RADUJKOVIC, Danijela, CAILLET-SAGUY, Célia, SIMISTER, Philip C, FRIEBE, Peter, WICHT, Oliver, KLEIN, Rahel, BARTENSCHLAGER, Ralf, LOHMANN, Volker

Volltext

Beyond ‘furballs’ and ‘dumpling soups’ – towards a molecular architecture of signaling complexes and networks von Lewitzky, Marc, Simister, Philip C., Feller, Stephan M.

Volltext

Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies von Simister, Philip C, Feller, Stephan M

Volltext

Self-organization and regulation of intrinsically disordered proteins with folded N-termini von Simister, Philip C, Schaper, Fred, O'Reilly, Nicola, McGowan, Simon, Feller, Stephan M

Volltext

Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3... von Rouka, Evgenia, Simister, Philip C., Janning, Melanie, Kumbrink, Joerg, Konstantinou, Tassos, Muniz, João R.C., Joshi, Dhira, O'Reilly, Nicola, Volkmer, Rudolf, Ritter, Brigitte, Knapp, Stefan, von Delft, Frank, Kirsch, Kathrin H., Feller, Stephan M.

Volltext

Inhibiting Helicobacter pylori HtrA protease by addressing a computationally predicted allosteric ligand binding site von Perna, Anna Maria, Reisen, Felix, Schmidt, Thomas P, Geppert, Tim, Pillong, Max, Weisel, Martin, Hoy, Benjamin, Simister, Philip C, Feller, Stephan M, Wessler, Silja, Schneider, Gisbert

Volltext

Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis von Harrus, Déborah, Ahmed-El-Sayed, Neveen, Simister, Philip C., Miller, Steve, Triconnet, Martine, Hagedorn, Curt H., Mahias, Kathleen, Rey, Félix A., Astier-Gin, Thérèse, Bressanelli, Stéphane

Volltext

MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch von Wolf, Alexandra, Eulenfeld, René, Bongartz, Hannes, Hessenkemper, Wiebke, Simister, Philip C., Lievens, Sam, Tavernier, Jan, Feller, Stephan M., Schaper, Fred

Volltext

Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen von Simister, Philip C., Luccarelli, James, Thompson, Sam, Appella, Daniel H., Feller, Stephan M., Hamilton, Andrew D.

Volltext

Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the SH3C Domain of Grb2 von Harkiolaki, Maria, Tsirka, Theodora, Lewitzky, Marc, Simister, Philip C., Joshi, Dhira, Bird, Louise E., Jones, E. Yvonne, O'Reilly, Nicola, Feller, Stephan M.

Volltext

Structural and Functional Analysis of Hepatitis C Virus Strain JFH1 Polymerase von SIMISTER, Philip, SCHMITT, Melanie, GEITMANN, Matthis, WICHT, Oliver, HELENA DANIELSON, U, KLEIN, Rahel, BRESSANELLI, Stéphane, LOHMANN, Volker

Volltext

Interactions between Conserved Domains within Homodimers in the BIG1, BIG2, and GBF1 Arf Guanine Nucleotide Exchange Factors von Ramaen, Odile, Joubert, Alexandra, Simister, Philip, Belgareh-Touzé, Naïma, Olivares-Sanchez, Maria Conception, Zeeh, Jean-Christophe, Chantalat, Sophie, Golinelli-Cohen, Marie-Pierre, Jackson, Catherine L., Biou, Valérie, Cherfils, Jacqueline

Volltext

Application of ring-closing metathesis to Grb2 SH3 domain-binding peptides von Liu, Fa, Giubellino, Alessio, Simister, Philip C., Qian, Wenjian, Giano, Michael C., Feller, Stephan M., Bottaro, Donald P., Burke Jr, Terrence R.

Volltext

A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding von Bernegger, Sabine, Brunner, Cyrill, Vizovišek, Matej, Fonovic, Marko, Cuciniello, Gaetano, Giordano, Flavia, Stanojlovic, Vesna, Jarzab, Miroslaw, Simister, Philip, Feller, Stephan M., Obermeyer, Gerhard, Posselt, Gernot, Turk, Boris, Cabrele, Chiara, Schneider, Gisbert, Wessler, Silja

Volltext