Reduction of Cyclic and Acyclic Diazene Derivatives by Azotobacter vinelandii Nitrogenase:  Diazirine and trans-Dimethyldiazene von McKenna, Charles E, Simeonov, Anton M, Eran, Henry, Bravo-Leerabhandh, Marjorie

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Catalytic Reduction of cis-Dimethyldiazene by the [MoFe3S4]3+ Clusters. The Four-Electron Reduction of a NN Bond by a Nitrogenase-Relevant Cluster and Implications for the Functio... von Malinak, Steven M, Simeonov, Anton M, Mosier, Patrick E, McKenna, Charles E, Coucouvanis, Dimitri

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A Convenient Phase-Transfer Method for Preparation of Pure cis-Dimethyldiazene (cis-Azomethane) in Aqueous Solution. Proton and Carbon NMR Studies of trans- and cis-Dimethyldiazene von Simeonov, Anton M, McKenna, Charles E

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Catalytic Reduction of cis -Dimethyldiazene by the [MoFe 3 S 4 ] 3+ Clusters. The Four-Electron Reduction of a NN Bond by a Nitrogenase-Relevant Cluster and Implications for the Fu... von Malinak, Steven M., Simeonov, Anton M., Mosier, Patrick E., McKenna, Charles E., Coucouvanis, Dimitri

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INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE AND HISTONE DEACETYLASE FOR TREATMENT OF CANCER von FERRER, Marc, TAWA, Gregory James, THAKUR, Ashish, SIMEONOV, Anton M, GREWAL, Gurmit

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Perspectives on the Mechanism of ATP Hydrolysis by Nitrogenase von Krause, Stephan O., Gutheil, William G., Simeonov, Anton M., Matsunaga, Terry O., Stauber, Margaret J., Kenyon, George L., Mckenna, Charles E.

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Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library von Cruz, Deu John M, Bonotto, Rafaela M, Gomes, Rafael G B, da Silva, Camila T, Taniguchi, Juliana B, No, Joo Hwan, Lombardot, Benoit, Schwartz, Olivier, Hansen, Michael A E, Freitas-Junior, Lucio H

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Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen von Xu, Miao, Lee, Emily M, Wen, Zhexing, Cheng, Yichen, Huang, Wei-Kai, Qian, Xuyu, TCW, Julia, Kouznetsova, Jennifer, Ogden, Sarah C, Hammack, Christy, Jacob, Fadi, Nguyen, Ha Nam, Itkin, Misha, Hanna, Catherine, Shinn, Paul, Allen, Chase, Michael, Samuel G, Simeonov, Anton, Huang, Wenwei, Christian, Kimberly M, Goate, Alison, Brennand, Kristen J, Huang, Ruili, Xia, Menghang, Ming, Guo-li, Zheng, Wei, Song, Hongjun, Tang, Hengli

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Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy von Stafford, WC, Peng, XX, Olofsson, MH, Zhang, XN, Luci, DK, Lu, L, Cheng, Q, Tresaugues, L, Dexheimer, TS, Coussens, NP, Augsten, M, Ahlzen, HSM, Orwar, O, Ostman, A, Stone-Elander, S, Maloney, DJ, Jadhav, A, Simeonov, A, Linder, S, Arner, ESJ

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Biological activity-based modeling identifies antiviral leads against SARS-CoV-2 von Huang, Ruili, Xu, Miao, Zhu, Hu, Chen, Catherine Z., Zhu, Wei, Lee, Emily M., He, Shihua, Zhang, Li, Zhao, Jinghua, Shamim, Khalida, Bougie, Danielle, Huang, Wenwei, Xia, Menghang, Hall, Mathew D., Lo, Donald, Simeonov, Anton, Austin, Christopher P., Qiu, Xiangguo, Tang, Hengli, Zheng, Wei

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Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions von Seidel, Susanne A.I., Dijkman, Patricia M., Lea, Wendy A., van den Bogaart, Geert, Jerabek-Willemsen, Moran, Lazic, Ana, Joseph, Jeremiah S., Srinivasan, Prakash, Baaske, Philipp, Simeonov, Anton, Katritch, Ilia, Melo, Fernando A., Ladbury, John E., Schreiber, Gideon, Watts, Anthony, Braun, Dieter, Duhr, Stefan

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A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells von Chen, Yu, Tristan, Carlos A., Chen, Lu, Jovanovic, Vukasin M., Malley, Claire, Chu, Pei-Hsuan, Ryu, Seungmi, Deng, Tao, Ormanoglu, Pinar, Tao, Dingyin, Fang, Yuhong, Slamecka, Jaroslav, Hong, Hyenjong, LeClair, Christopher A., Michael, Sam, Austin, Christopher P., Simeonov, Anton, Singeç, Ilyas

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A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth von Wang, Lei, Chang, Jianjun, Varghese, Diana, Dellinger, Michael, Kumar, Subodh, Best, Anne M., Ruiz, Julio, Bruick, Richard, Peña-Llopis, Samuel, Xu, Junjie, Babinski, David J., Frantz, Doug E., Brekken, Rolf A., Quinn, Amy M., Simeonov, Anton, Easmon, Johnny, Martinez, Elisabeth D.

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Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH) von Rai, Ganesha, Brimacombe, Kyle R, Mott, Bryan T, Urban, Daniel J, Hu, Xin, Yang, Shyh-Ming, Lee, Tobie D, Cheff, Dorian M, Kouznetsova, Jennifer, Benavides, Gloria A, Pohida, Katie, Kuenstner, Eric J, Luci, Diane K, Lukacs, Christine M, Davies, Douglas R, Dranow, David M, Zhu, Hu, Sulikowski, Gary, Moore, William J, Stott, Gordon M, Flint, Andrew J, Hall, Matthew D, Darley-Usmar, Victor M, Neckers, Leonard M, Dang, Chi V, Waterson, Alex G, Simeonov, Anton, Jadhav, Ajit, Maloney, David J

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells von Griner, Lesley A. Mathews, Guha, Rajarshi, Shinn, Paul, Young, Ryan M., Keller, Jonathan M., Liu, Dongbo, Goldlust, Ian S., Yasgar, Adam, McKnight, Crystal, Boxer, Matthew B., Duveau, Damien Y., Jiang, Jian-Kang, Michael, Sam, Mierzwa, Tim, Huang, Wenwei, Walsh, Martin J., Mott, Bryan T., Patel, Paresma, Leister, William, Maloney, David J., Leclair, Christopher A., Rai, Ganesha, Jadhav, Ajit, Peyser, Brian D., Austin, Christopher P., Martin, Scott E., Simeonov, Anton, Ferrer, Marc, Staudt, Louis M., Thomas, Craig J.

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Unexplored therapeutic opportunities in the human genome von Oprea, Tudor I., Bologa, Cristian G., Brunak, Søren, Campbell, Allen, Gan, Gregory N., Gaulton, Anna, Gomez, Shawn M., Guha, Rajarshi, Hersey, Anne, Holmes, Jayme, Jadhav, Ajit, Jensen, Lars Juhl, Johnson, Gary L., Karlson, Anneli, Leach, Andrew R., Ma'ayan, Avi, Malovannaya, Anna, Mani, Subramani, Mathias, Stephen L., McManus, Michael T., Meehan, Terrence F., von Mering, Christian, Muthas, Daniel, Nguyen, Dac-Trung, Overington, John P., Papadatos, George, Qin, Jun, Reich, Christian, Roth, Bryan L., Schürer, Stephan C., Simeonov, Anton, Sklar, Larry A., Southall, Noel, Tomita, Susumu, Tudose, Ilinca, Ursu, Oleg, Vidović, Dušica, Waller, Anna, Westergaard, David, Yang, Jeremy J., Zahoránszky-Köhalmi, Gergely

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Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor von Paul, Debasish, Kales, Stephen C., Cornwell, James A., Afifi, Marwa M., Rai, Ganesha, Zakharov, Alexey, Simeonov, Anton, Cappell, Steven D.

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Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2 von Chen, Catherine Z., Shinn, Paul, Itkin, Zina, Eastman, Richard T., Bostwick, Robert, Rasmussen, Lynn, Huang, Ruili, Shen, Min, Hu, Xin, Wilson, Kelli M., Brooks, Brianna M., Guo, Hui, Zhao, Tongan, Klump-Thomas, Carleen, Simeonov, Anton, Michael, Samuel G., Lo, Donald C., Hall, Matthew D., Zheng, Wei

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Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes von Yan, Wenjing, Zhong, Yongwang, Hu, Xin, Xu, Tuan, Zhang, Yinghua, Kales, Stephen, Qu, Yanyan, Talley, Daniel C., Baljinnyam, Bolormaa, LeClair, Christopher A., Simeonov, Anton, Polster, Brian M., Huang, Ruili, Ye, Yihong, Rai, Ganesha, Henderson, Mark J., Tao, Dingyin, Fang, Shengyun

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Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites von Dorjsuren, Dorjbal, Eastman, Richard T., Wicht, Kathryn J., Jansen, Daniel, Talley, Daniel C., Sigmon, Benjamin A., Zakharov, Alexey V., Roncal, Norma, Girvin, Andrew T., Antonova-Koch, Yevgeniya, Will, Paul M., Shah, Pranav, Sun, Hongmao, Klumpp-Thomas, Carleen, Mok, Sachel, Yeo, Tomas, Meister, Stephan, Marugan, Juan Jose, Ross, Leila S., Xu, Xin, Maloney, David J., Jadhav, Ajit, Mott, Bryan T., Sciotti, Richard J., Winzeler, Elizabeth A., Waters, Norman C., Campbell, Robert F., Huang, Wenwei, Simeonov, Anton, Fidock, David A.

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