Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells von Douvaras, Panagiotis, Wang, Jing, Zimmer, Matthew, Hanchuk, Stephanie, O’Bara, Melanie A., Sadiq, Saud, Sim, Fraser J., Goldman, James, Fossati, Valentina

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Human iPSC-derived myelinating organoids and globoid cells to study Krabbe disease von Evans, Lisa Marie P, Gawron, Joseph, Sim, Fraser J, Feltri, M Laura, Marziali, Leandro N

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CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells von Sim, Fraser J, Goldman, Steven A, McClain, Crystal R, Schanz, Steven J, Protack, Tricia L, Windrem, Martha S

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The Transcriptome and Metabolic Gene Signature of Protoplasmic Astrocytes in the Adult Murine Cortex von Lovatt, Ditte, Sonnewald, Ursula, Waagepetersen, Helle S, Schousboe, Arne, He, Wei, Lin, Jane H.-C, Han, Xiaoning, Takano, Takahiro, Wang, Su, Sim, Fraser J, Goldman, Steven A, Nedergaard, Maiken

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Clemastine Induces Oligodendrocyte Progenitor Pool Exhaustion and Senescence in the Context of Chronic Demyelination in a Rabbit Model von Cooper, James J M, Muthaiah, Rupadevi, Frost, Jon R, Buck, Gregory T, Ravichandar, Roopa, Gadelkarim, Farah, Raymond, Faye D, Sim, Fraser J

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Transcription factor induction of human oligodendrocyte progenitor fate and differentiation von Wang, Jing, Pol, Suyog U, Haberman, Alexa K, Wang, Chunming, O'Bara, Melanie A, Sim, Fraser J

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Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination von Tripathi, Ajai, Volsko, Christina, Garcia, Jessie P., Agirre, Eneritz, Allan, Kevin C., Tesar, Paul J., Trapp, Bruce D., Castelo-Branco, Goncalo, Sim, Fraser J., Dutta, Ranjan

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p38γ MAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions von Marziali, Leandro N, Hwang, Yoonchan, Palmisano, Marilena, Cuenda, Ana, Sim, Fraser J, Gonzalez, Alberto, Volsko, Christina, Dutta, Ranjan, Trapp, Bruce D, Wrabetz, Lawrence, Feltri, Maria L

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Differential gene expression by endothelial cells under positive and negative streamwise gradients of high wall shear stress von Dolan, Jennifer M, Meng, Hui, Sim, Fraser J, Kolega, John

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Endothelial cells express a unique transcriptional profile under very high wall shear stress known to induce expansive arterial remodeling von Dolan, Jennifer M, Sim, Fraser J, Meng, Hui, Kolega, John

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Targeting human oligodendrocyte progenitors for myelin repair von Dietz, Karen C., Polanco, Jessie J., Pol, Suyog U., Sim, Fraser J.

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Chronic demyelination of rabbit lesions is attributable to failed oligodendrocyte progenitor cell repopulation von Cooper, James J. M., Polanco, Jessie J., Saraswat, Darpan, Peirick, Jennifer J., Seidl, Anna, Li, Yi, Ma, Dan, Sim, Fraser J.

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Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells von Seidman, Richard A., Khattab, Heba, Polanco, Jessie J., Broome, Jacqueline E., Sim, Fraser J.

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Heparanome-Mediated Rescue of Oligodendrocyte Progenitor Quiescence following Inflammatory Demyelination von Saraswat, Darpan, Welliver, R Ross, Ravichandar, Roopa, Tripathi, Ajai, Polanco, Jessie J, Broome, Jacqueline, Hurley, Edward, Dutta, Ranjan, Feltri, M Laura, Sim, Fraser J

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Hyaluronan accumulation and arrested oligodendrocyte progenitor maturation in vanishing white matter disease von BUGIANI, Marianna, POSTMA, Nienke, POLDER, Emiel, DIELEMAN, Nikki, SCHEFFER, Peter G, SIM, Fraser J, DER KNAAP, Marjo S. Van, BOOR, Ilja

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Transcriptional Differences between Normal and Glioma-Derived Glial Progenitor Cells Identify a Core Set of Dysregulated Genes von Auvergne, Romane M., Sim, Fraser J., Wang, Su, Chandler-Militello, Devin, Burch, Jaclyn, Al Fanek, Yazan, Davis, Danielle, Benraiss, Abdellatif, Walter, Kevin, Achanta, Pragathi, Johnson, Mahlon, Quinones-Hinojosa, Alfredo, Natesan, Sridaran, Ford, Heide L., Goldman, Steven A.

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Anti-muscarinic adjunct therapy accelerates functional human oligodendrocyte repair von Abiraman, Kavitha, Pol, Suyog U, O'Bara, Melanie A, Chen, Guang-Di, Khaku, Zainab M, Wang, Jing, Thorn, David, Vedia, Bansi H, Ekwegbalu, Ezinne C, Li, Jun-Xu, Salvi, Richard J, Sim, Fraser J

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Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination von Saraswat, Darpan, Shayya, Hani J., Polanco, Jessie J., Tripathi, Ajai, Welliver, R. Ross, Pol, Suyog U., Seidman, Richard A., Broome, Jacqueline E., O’Bara, Melanie A., van Kuppervelt, Toin H., Phillips, Joanna J., Dutta, Ranjan, Sim, Fraser J.

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EGR3 regulates opioid-related nociception and motivation in male rats von Mitra, Swarup, Thomas, Shruthi A., Martin, Jennifer A., Williams, Jamal, Woodhouse, Kristen, Chandra, Ramesh, Li, Jun Xu, Lobo, Mary Kay, Sim, Fraser J., Dietz, David M.

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Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors von Wang, Jing, Saraswat, Darpan, Sinha, Anjali K., Polanco, Jessie, Dietz, Karen, O’Bara, Melanie A., Pol, Suyog U., Shayya, Hani J., Sim, Fraser J.

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