Discovery and Synthesis of Hydroxy-l-Proline Blockers of the Neutral Amino Acid Transporters SLC1A4 (ASCT1) and SLC1A5 (ASCT2) von Lyda, Brent R, Leary, Gregory P, Farnsworth, Jill, Seaver, Benjamin, Silvius, Derek, Kavanaugh, Michael P, Esslinger, C Sean, Natale, Nicholas R

Volltext

Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes von Zou, Dan, Silvius, Derek, Fritzsch, Bernd, Xu, Pin-Xian

Volltext

Six1 is required for the early organogenesis of mammalian kidney von Xu, Pin-Xian, Zheng, Weiming, Huang, Li, Maire, Pascal, Laclef, Christine, Silvius, Derek

Volltext

The role of Six1 in mammalian auditory system development von Zheng, Weiming, Huang, Li, Wei, Zhu-Bo, Silvius, Derek, Tang, Bihui, Xu, Pin-Xian

Volltext

SIX1 Mutations Cause Branchio-Oto-Renal Syndrome by Disruption of EYA1-SIX1-DNA Complexes von Ruf, Rainer G., Xu, Pin-Xian, Silvius, Derek, Otto, Edgar A., Beekmann, Frank, Muerb, Ulla T., Kumar, Shrawan, Neuhaus, Thomas J., Kemper, Markus J., Raymond, Richard M., Brophy, Patrick D., Berkman, Jennifer, Gattas, Michael, Hyland, Valentine, Ruf, Eva-Maria, Schwartz, Charles, Chang, Eugene H., Richard J. H. Smith, Stratakis, Constantine A., Weil, Dominique, Petit, Christine, Hildebrandt, Friedhelm, Weissman, Irving L.

Volltext

Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease von Silvius, Derek, Pitstick, Rose, Ahn, Misol, Meishery, Delisha, Oehler, Abby, Barsh, Gregory S, DeArmond, Stephen J, Carlson, George A, Gunn, Teresa M

Volltext

Discovery and Synthesis of Hydroxy-l-Proline Blockers of the Neutral Amino Acid Transporters SLC1A4 von Lyda, Brent R, Leary, Gregory P, Farnsworth, Jill, Seaver, Benjamin, Silvius, Derek, Kavanaugh, Michael P, Esslinger, C. Sean, Natale, Nicholas R

Volltext

Generation and characterization of a knock-in mouse model for spastic tetraplegia, thin corpus callosum, and progressive microcephaly (SPATCCM) von Ratz-Mitchem, Megan L., Leary, Greg, Grindeland, Andrea, Silvius, Derek, Guter, Joseph, Kavanaugh, Michael P., Gunn, Teresa M.

Volltext

Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease von Vallabh, Sonia M, Zou, Dan, Pitstick, Rose, O'Moore, Jill, Peters, Janet, Silvius, Derek, Kriz, Jasna, Jackson, Walker S, Carlson, George A, Minikel, Eric Vallabh, Cabin, Deborah E

Volltext

Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis von Gunn, Teresa M., Silvius, Derek, Lester, Andrew, Gibbs, Britney

Volltext

Spermatid nuclear and sperm periaxonemal anomalies in the mouse Ube2b null mutant von Escalier, Denise, Bai, Xi-Yuan, Silvius, Derek, Xu, Pin-Xian, Xu, Xin

Volltext

Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1 von Zou, Dan, Silvius, Derek, Davenport, Julie, Grifone, Raphaelle, Maire, Pascal, Xu, Pin-Xian

Volltext

Eya1 acts as a critical regulator for specifying the metanephric mesenchyme von Sajithlal, Gangadharan, Zou, Dan, Silvius, Derek, Xu, Pin-Xian

Volltext

Transcription Factor SIX5 Is Mutated in Patients with Branchio-Oto-Renal Syndrome von Hoskins, Bethan E., Cramer, Carl H., Silvius, Derek, Zou, Dan, Raymond, Richard M., Orten, Dana J., Kimberling, William J., Smith, Richard J.H., Weil, Dominique, Petit, Christine, Otto, Edgar A., Xu, Pin-Xian, Hildebrandt, Friedhelm

Volltext

Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear von Zou, Dan, Silvius, Derek, Rodrigo-Blomqvist, Sandra, Enerbäck, Sven, Xu, Pin-Xian

Volltext

MGRN1-dependent pigment-type switching requires its ubiquitination activity but not its interaction with TSG101 or NEDD4 von Gunn, Teresa M., Silvius, Derek, Bagher, Pooneh, Sun, Kaihua, Walker, Katherine K.

Volltext

Spermatogenesis of mice lacking CK2α′: Failure of germ cell survival and characteristic modifications of the spermatid nucleus von Escalier, Denise, Silvius, Derek, Xu, Xin

Volltext

MGRN 1‐dependent pigment‐type switching requires its ubiquitination activity but not its interaction with TSG 101 or NEDD 4 von Gunn, Teresa M., Silvius, Derek, Bagher, Pooneh, Sun, Kaihua, Walker, Katherine K.

Volltext

Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2 von Bai, Xiyuan, Silvius, Derek, Chan, Edward D, Escalier, Denise, Xu, Shaun Xin

Volltext

Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice von Anderson, Sarah R, Lee, Inyoul, Ebeling, Christine, Stephenson, Dennis A, Schweitzer, Kelsey M, Baxter, David, Moon, Tara M, LaPierre, Sarah, Jaques, Benjamin, Silvius, Derek, Wegner, Michael, Hood, Leroy E, Carlson, George, Gunn, Teresa M

Volltext