Monoacylglycerol lipase (MAGL) as a promising therapeutic target von Gil-Ordóñez, Ana, Martín-Fontecha, Mar, Ortega-Gutiérrez, Silvia, López-Rodríguez, María L.

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New Pharmacological Approaches for Rare Diseases von Ortega-Gutiérrez, Silvia

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Chemistry for the Identification of Therapeutic Targets: Recent Advances and Future Directions von Khiar‐Fernández, Nora, Macicior, Jon, Marcos‐Ramiro, Beatriz, Ortega‐Gutiérrez, Silvia

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Small-Molecule Therapeutic Perspectives for the Treatment of Progeria von Macicior, Jon, Marcos-Ramiro, Beatriz, Ortega-Gutiérrez, Silvia

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A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration von González-Gil, Inés, Zian, Debora, Vázquez-Villa, Henar, Hernández-Torres, Gloria, Martínez, R. Fernando, Khiar-Fernández, Nora, Rivera, Richard, Kihara, Yasuyuki, Devesa, Isabel, Mathivanan, Sakthikumar, del Valle, Cristina Rosell, Zambrana-Infantes, Emma, Puigdomenech, María, Cincilla, Giovanni, Sanchez-Martinez, Melchor, Rodríguez de Fonseca, Fernando, Ferrer-Montiel, Antonio V, Chun, Jerold, López-Vales, Rubén, López-Rodríguez, María L, Ortega-Gutiérrez, Silvia

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A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia von Marín-Ramos, Nagore I, Balabasquer, Moisés, Ortega-Nogales, Francisco J, Torrecillas, Iván R, Gil-Ordóñez, Ana, Marcos-Ramiro, Beatriz, Aguilar-Garrido, Pedro, Cushman, Ian, Romero, Antonio, Medrano, Francisco J, Gajate, Consuelo, Mollinedo, Faustino, Philips, Mark R, Campillo, Mercedes, Gallardo, Miguel, Martín-Fontecha, Mar, López-Rodríguez, María L, Ortega-Gutiérrez, Silvia

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CB1 Cannabinoid Receptors and On-Demand Defense against Excitotoxicity von Marsicano, Giovanni, Goodenough, Sharon, Monory, Krisztina, Hermann, Heike, Eder, Matthias, Cannich, Astrid, Azad, Shahnaz C., Cascio, Maria Grazia, Gutiérrez, Silvia Ortega, van der Stelt, Mario, López-Rodríguez, Maria Luz, Casanova, Emilio, Schütz, Günther, Zieglgänsberger, Walter, Di Marzo, Vincenzo, Behl, Christian, Lutz, Beat

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A new fluorescent probe for the visualization of progerin von Macicior, Jon, Fernández, Daniel, Ortega-Gutiérrez, Silvia

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Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice von Khiar-Fernández, Nora, Zian, Debora, Vázquez-Villa, Henar, Martínez, R. Fernando, Escobar-Peña, Andrea, Foronda-Sainz, Román, Ray, Manisha, Puigdomenech-Poch, Maria, Cincilla, Giovanni, Sánchez-Martínez, Melchor, Kihara, Yasuyuki, Chun, Jerold, López-Vales, Rubèn, López-Rodríguez, María L., Ortega-Gutiérrez, Silvia

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Ligand chain length drives activation of lipid G protein-coupled receptors von Troupiotis-Tsaïlaki, Anastassia, Zachmann, Julian, González-Gil, Inés, Gonzalez, Angel, Ortega-Gutiérrez, Silvia, López-Rodríguez, Maria L., Pardo, Leonardo, Govaerts, Cedric

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A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB1 in Human Blood and Tonsil Immune System Cells von Martín-Fontecha, Mar, Angelina, Alba, Rückert, Beate, Rueda-Zubiaurre, Ainoa, Martín-Cruz, Leticia, van de Veen, Willem, Akdis, Mübeccel, Ortega-Gutiérrez, Silvia, López-Rodríguez, María Luz, Akdis, Cezmi A, Palomares, Oscar

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Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson–Gilford Progeria Syndrome von Marcos-Ramiro, Beatriz, Gil-Ordóñez, Ana, Marín-Ramos, Nagore I, Ortega-Nogales, Francisco J, Balabasquer, Moisés, Gonzalo, Pilar, Khiar-Fernández, Nora, Rolas, Loïc, Barkaway, Anna, Nourshargh, Sussan, Andrés, Vicente, Martín-Fontecha, Mar, López-Rodríguez, María L, Ortega-Gutiérrez, Silvia

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New Synthetic Inhibitors of Fatty Acid Synthase with Anticancer Activity von Turrado, Carlos, Puig, Teresa, García-Cárceles, Javier, Artola, Marta, Benhamú, Bellinda, Ortega-Gutiérrez, Silvia, Relat, Joana, Oliveras, Gloria, Blancafort, Adriana, Haro, Diego, Marrero, Pedro F, Colomer, Ramón, López-Rodríguez, María L

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New Trends in Aging Drug Discovery von Benhamú, Bellinda, Martín-Fontecha, Mar, Vázquez-Villa, Henar, López-Rodríguez, María L, Ortega-Gutiérrez, Silvia

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New Inhibitors of Angiogenesis with Antitumor Activity in Vivo von Marín-Ramos, Nagore I, Alonso, Dulce, Ortega-Gutiérrez, Silvia, Ortega-Nogales, Francisco J, Balabasquer, Moisés, Vázquez-Villa, Henar, Andradas, Clara, Blasco-Benito, Sandra, Pérez-Gómez, Eduardo, Canales, Ángeles, Jiménez-Barbero, Jesús, Marquina, Ana, del Prado, Jaime Moscoso, Sánchez, Cristina, Martín-Fontecha, Mar, López-Rodríguez, María L

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Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis von Ortega-Gutiérrez, Silvia, Molina-Holgado, Eduardo, Arévalo-Martín, Ángel, Correa, Fernando, Viso, Alma, López-Rodríguez, María L, Di Marzo, Vincenzo, Guaza, Carmen

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Structure–Activity Relationship of a New Series of Reversible Dual Monoacylglycerol Lipase/Fatty Acid Amide Hydrolase Inhibitors von Cisneros, José A, Björklund, Emmelie, González-Gil, Inés, Hu, Yanling, Canales, Ángeles, Medrano, Francisco J, Romero, Antonio, Ortega-Gutiérrez, Silvia, Fowler, Christopher J, López-Rodríguez, María L

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Development of Endocannabinoid-Based Chemical Probes for the Study of Cannabinoid Receptors von Martín-Couce, Lidia, Martín-Fontecha, Mar, Capolicchio, Samanta, López-Rodríguez, María L, Ortega-Gutiérrez, Silvia

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Inside Cover: A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis (Angew. Chem. Int. Ed. 50/2014) von Hernández-Torres, Gloria, Cipriano, Mariateresa, Hedén, Erika, Björklund, Emmelie, Canales, Ángeles, Zian, Debora, Feliú, Ana, Mecha, Miriam, Guaza, Carmen, Fowler, Christopher J., Ortega-Gutiérrez, Silvia, López-Rodríguez, María L.

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Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice von Ortega-Gutiérrez, Silvia, Leung, Donmienne, Ficarro, Scott, Peters, Eric C, Cravatt, Benjamin F

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