1411 CF102 FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA: A PHASE I/II, OPEN-LABEL, DOSE-ESCALATION STUDY von Stemmer, S.M, Benjaminov, O, Medalia, G, Ciuraru, N.B, Silverman, M.H, Bar-Yehuda, S, Fishman, S, Harpaz, Z, Farbstein, M, Cohen, S, Patoka, R, Singer, B, Kerns, W.D, Fishman, P

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Treatment of plaque-type psoriasis with oral CF101: data from an exploratory randomized phase 2 clinical trial von David, M., Akerman, L., Ziv, M., Kadurina, M., Gospodinov, D., Pavlotsky, F., Yankova, R., Kouzeva, V., Ramon, M., Silverman, M.H., Fishman, P.

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Safety, Tolerability and Pharmacokinetics of Icapamespib, a Selective Epichaperome Inhibitor, in Healthy Adults von Silverman, M. H., Duggan, S., Bardelli, Geraldine, Sadler, B., Key, C., Medlock, M., Reynolds, L., Wallner, B.

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384 Phase 1/2 trial of CF102, a selective A3 adenosine receptor (A3AR) agonist, in patients with hepatocellular carcinoma (HCC) von Stemmer, S, Silverman, M.H, Kerns, W.D, Yehuda, S. Bar, Fishman, S, Harpaz, Z, Farbstein, M, Binyaminov, O, Medalia, G, Fishman, P

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571 TLC388, a novel topoisomerase-1 inhibitor with anti-hypoxia inducible factor-1 alpha activity: a phase I and pharmacokinetic study in patients with advanced solid malignancies von Lin, C, Ghamande, S.A, Cho, D.C, Silverman, M.H, Fong, K, Kuo, M, Mach, W, Tseng, Y, Hsu, S.C, Goel, S

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575 ALB 109564(a), a novel tubulin inhibitor: phase 1 trial in patients with solid tumours von Clancy, M.S, Cleary, J.M, Mani, S, Choy, E, Wolf, M.A, Silverman, M.H, Gad, S.C, Cuasay, L.C, Dezube, B.J, Shapiro, G.I

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170 A6, a urokinase plasminogen activator (uPA)-derived peptide: a phase I trial in patients with advanced gynecologic cancer von Berkenblit, A., Gold, M.A., Matulonis, U.A., Kroener, J.F., Dezube, B.J., Lam, G.N., Brünner, N., Jones, T.R., Silverman, M.H.

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Implications of Race Adjustment in Lung-Function Equations von Diao, James A., He, Yixuan, Khazanchi, Rohan, Nguemeni Tiako, Max Jordan, Witonsky, Jonathan I., Pierson, Emma, Rajpurkar, Pranav, Elhawary, Jennifer R., Melas-Kyriazi, Luke, Yen, Albert, Martin, Alicia R., Levy, Sean, Patel, Chirag J., Farhat, Maha, Borrell, Luisa N., Cho, Michael H., Silverman, Edwin K., Burchard, Esteban G., Manrai, Arjun K.

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Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma von McGeachie, Michael J, Yates, Katherine P, Zhou, Xiaobo, Guo, Feng, Sternberg, Alice L, Van Natta, Mark L, Wise, Robert A, Szefler, Stanley J, Sharma, Sunita, Kho, Alvin T, Cho, Michael H, Croteau-Chonka, Damien C, Castaldi, Peter J, Jain, Gaurav, Sanyal, Amartya, Zhan, Ye, Lajoie, Bryan R, Dekker, Job, Stamatoyannopoulos, John, Covar, Ronina A, Zeiger, Robert S, Adkinson, N. Franklin, Williams, Paul V, Kelly, H. William, Grasemann, Hartmut, Vonk, Judith M, Koppelman, Gerard H, Postma, Dirkje S, Raby, Benjamin A, Houston, Isaac, Lu, Quan, Fuhlbrigge, Anne L, Tantisira, Kelan G, Silverman, Edwin K, Tonascia, James, Weiss, Scott T, Strunk, Robert C

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Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease von Serban, K.A., Pratte, K.A., Strange, C., Sandhaus, R.A., Turner, A.M., Beiko, T., Spittle, D.A., Maier, L., Hamzeh, N., Silverman, E.K., Hobbs, B.D., Hersh, C.P., DeMeo, D.L., Cho, M.H., Bowler, R.P.

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717TiP Randomized, open-label, 3-arm phase III study comparing MK-1308A + lenvatinib and pembrolizumab (pembro) + belzutifan + lenvatinib versus pembro + lenvatinib as first-line (... von Rini, B.I., Plimack, E.R., Powles, T.B., Voss, M.H., Gurney, H.P., Silverman, R., Perini, R., Rodriguez-Lopez, K., Choueiri, T.K.

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Organ Preservation in Patients With Orbit-Invasive Sinonasal Cancer von Yusuf, M.B, Amsbaugh, M.J, Silverman, C.L, Bumpous, J, Perez, C.A, Potts, K, Tennant, P, Redman, R, Bertke, M.H, Dunlap, N.E

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Acceptability of Supplemental Progesterone to Prevent Preterm Labor and Low Birth Weight in Pregnant Zambian Women [32D] von Wong, Jeffrey M.H., Dogra, Nupur, Kanga, Neha, Ngoma, Mary, Serghides, Lena, Silverman, Michael

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HPV Status May Have Limited Value as a Prognostic Factor in Postoperative Squamous Cell Carcinoma of the Head and Neck Compared to Extranodal Extension and Lymphovascular Space Inv... von Bertke, M.H, Shaughnessy, J.N, Forsthoefel, M.K, Cash, E, Silverman, C.L, Amsbaugh, M.J, Bumpous, J, Potts, K, Redman, R, Perez, C.A, Dunlap, N.E

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HPV Status May Alter the Significance of Extranodal Extension as a Negative Prognostic Factor in Postoperative Squamous Cell Carcinoma of the Head and Neck von Bertke, M.H, Shaughnessy, J.N, Aya, S.R, Cash, E.D, Silverman, C.L, Bumpous, J.M, Potts, K.L, Redman, R.A, Wilson, L.D, Dunlap, N.E

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OC-042: Definitive chemoradiotherapy: An alternative to surgery in stage III/IV squamous cell carcinoma of the oral cavity? von Bertke, M.H, Dunlap, N.E, Amsbaugh, M.J, Silverman, C.L, Bumpous, J.M, Potts, K.L, Redman, R.A, Shaughnessy, J.N

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Early determinants of atherosclerosis in paediatric systemic lupus erythematosus von BOROS, C. A, BRADLEY, T. J, CHEUNG, M. M. H, BARGMAN, J. M, RUSSELL, J. L, MCCRINDLE, B. W, ADELI, K, HAMILTON, J, SILVERMAN, E. D

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Genetic association between human chitinases and lung function in COPD von Aminuddin, F., Akhabir, L., Stefanowicz, D., Paré, P. D., Connett, J. E., Anthonisen, N. R., Fahy, J. V., Seibold, M. A., Burchard, E. G., Eng, C., Gulsvik, A., Bakke, P., Cho, M. H., Litonjua, A., Lomas, D. A., Anderson, W. H., Beaty, T. H., Crapo, J. D., Silverman, E. K., Sandford, A. J.

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The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle von Shaw, J.A. (National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD), Mol, P.C, Bowers, B, Silverman, S.J, Valdivieso, M.H, Duran, A, Cabib, E

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Nikkomycin Z is a specific inhibitor of Saccharomyces cerevisiae chitin synthase isozyme Chs3 in vitro and in vivo von Gaughran, J.P, Lai, M.H, Kirsch, D.R, Silverman, S.J

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