Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector von Mantilla, Brian S, Marchese, Letícia, Casas-Sánchez, Aitor, Dyer, Naomi A, Ejeh, Nicholas, Biran, Marc, Bringaud, Frédéric, Lehane, Michael J, Acosta-Serrano, Alvaro, Silber, Ariel M

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Carbohydrate metabolism in trypanosomatids: New insights revealing novel complexity, diversity and species-unique features von Michels, Paul A.M., Villafraz, Oriana, Pineda, Erika, Alencar, Mayke B., Cáceres, Ana J., Silber, Ariel M., Bringaud, Frédéric

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Natural products as a source for treating neglected parasitic diseases von Ndjonka, Dieudonné, Rapado, Ludmila Nakamura, Silber, Ariel M, Liebau, Eva, Wrenger, Carsten

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Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline von Villafraz, Oriana, Biran, Marc, Pineda, Erika, Plazolles, Nicolas, Cahoreau, Edern, Ornitz Oliveira Souza, Rodolpho, Thonnus, Magali, Allmann, Stefan, Tetaud, Emmanuel, Rivière, Loïc, Silber, Ariel M, Barrett, Michael P, Zíková, Alena, Boshart, Michael, Portais, Jean-Charles, Bringaud, Frédéric

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Nucleosome landscape reflects phenotypic differences in Trypanosoma cruzi life forms von Lima, Alex R J, de Araujo, Christiane B, Bispo, Saloe, Patané, José, Silber, Ariel M, Elias, M Carolina, da Cunha, Julia P C

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Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi von Shiratsubaki, Isabel S, Fang, Xin, Souza, Rodolpho O O, Palsson, Bernhard O, Silber, Ariel M, Siqueira-Neto, Jair L

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Proteome and morphological analysis show unexpected differences between promastigotes of Leishmania amazonensis PH8 and LV79 strains von Tano, Fabia Tomie, Barbosa, Gustavo Rolim, de Rezende, Eloiza, Souza, Rodolpho Ornitz Oliveira, Muxel, Sandra Marcia, Silber, Ariel Mariano, Palmisano, Giuseppe, Stolf, Beatriz Simonsen

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Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi von Souza, Rodolpho Ornitz Oliveira, Damasceno, Flávia Silva, Marsiccobetre, Sabrina, Biran, Marc, Murata, Gilson, Curi, Rui, Bringaud, Frédéric, Silber, Ariel Mariano

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Responsible Science Assessment: downplaying indexes, boosting quality von Kowaltowski, Alicia J, Silber, Ariel M, Oliveira, Marcus F

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The Trypanosoma cruzi TcrNT2 Nucleoside Transporter Is a Conduit for the Uptake of 5-F-2'-Deoxyuridine and Tubercidin Analogues von Aldfer, Mustafa M, Alfayez, Ibrahim A, Elati, Hamza A A, Gayen, Nilanjana, Elmahallawy, Ehab Kotb, Milena Murillo, Ana, Marsiccobetre, Sabrina, Van Calenbergh, Serge, Silber, Ariel M, de Koning, Harry P

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Actions of a proline analogue, L-thiazolidine-4-carboxylic acid (T4C), on Trypanosoma cruzi von Magdaleno, Anahí, Ahn, Il-Young, Paes, Lisvane Silva, Silber, Ariel M

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How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell von Nascimento, Janaina F, Souza, Rodolpho O O, Alencar, Mayke B, Marsiccobetre, Sabrina, Murillo, Ana M, Damasceno, Flávia S, Girard, Richard B M M, Marchese, Letícia, Luévano-Martinez, Luis A, Achjian, Renan W, Haanstra, Jurgen R, Michels, Paul A M, Silber, Ariel M

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Computational approaches for drug discovery against trypanosomatid-caused diseases von Pereira, Claudio A, Sayé, Melisa, Reigada, Chantal, Silber, Ariel M, Labadie, Guillermo R, Miranda, Mariana R, Valera-Vera, Edward

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Crystal structure of histidine ammonia-lyase from Trypanosoma cruzi von Miranda, Robson R., Silva, Marcio, Barisón, Maria J., Silber, Ariel M., Iulek, Jorge

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Protein kinases on carbon metabolism: potential targets for alternative chemotherapies against toxoplasmosis von Dos Santos, Denis Amilton, Souza, Higo Fernando Santos, Silber, Ariel M, de Souza, Tatiana de Arruda Campos Brasil, Ávila, Andréa Rodrigues

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The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids von Marchese, Letícia, Nascimento, Janaina de Freitas, Damasceno, Flávia Silva, Bringaud, Frédéric, Michels, Paul A M, Silber, Ariel Mariano

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Abnormal sterol-induced cell wall glucan deficiency in yeast is due to impaired glucan synthase transport to the plasma membrane von Gutierrez-Armijos, Roxana, Sussmann, Rodrigo Antonio Ceschini, Silber, Ariel Mariano, Cortez, Mauro, Hernandez, Agustin

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Cloning and characterisation of the Equilibrative Nucleoside Transporter family of Trypanosoma cruzi: ultra-high affinity and selectivity to survive in the intracellular niche von Campagnaro, Gustavo D., de Freitas Nascimento, Janaína, Girard, Richard B.M., Silber, Ariel M., de Koning, Harry P.

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Higher expression of proline dehydrogenase altered mitochondrial function and increased Trypanosoma cruzi differentiation in vitro and in the insect vector von Mantilla, Brian S, Paes-Vieira, Lisvane, de Almeida Dias, Felipe, Calderano, Simone G, Elias, Maria Carolina, Cosentino-Gomes, Daniela, Oliveira, Pedro L, Meyer-Fernandes, José Roberto, Silber, Ariel M

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The crystal structure of AjiA1 reveals a novel structural motion mechanism in the adenylate‐forming enzyme family von de Paiva, Fernanda C. R., Chan, Karen, Samborskyy, Markiyan, Silber, Ariel M., Leadlay, Peter F., Dias, Marcio V. B.

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