Design, Synthesis, and Phenotypic Profiling of Pyrano‐Furo‐Pyridone Pseudo Natural Products von Christoforow, Andreas, Wilke, Julian, Binici, Aylin, Pahl, Axel, Ostermann, Claude, Sievers, Sonja, Waldmann, Herbert

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Natural product fragment combination to performance-diverse pseudo-natural products von Grigalunas, Michael, Burhop, Annina, Zinken, Sarah, Pahl, Axel, Gally, José-Manuel, Wild, Niklas, Mantel, Yannik, Sievers, Sonja, Foley, Daniel J., Scheel, Rebecca, Strohmann, Carsten, Antonchick, Andrey P., Waldmann, Herbert

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Assessing biologic/toxicologic effects of extractables from plastic contact materials for advanced therapy manufacturing using cell painting assay and cytotoxicity screening von Pahl, Ina, Pahl, Axel, Hauk, Armin, Budde, Dana, Sievers, Sonja, Fruth, Lothar, Menzel, Roberto

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A Scaffold‐Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides von Zimmermann, Stefan, Akbarzadeh, Mohammad, Otte, Felix, Strohmann, Carsten, Sankar, Muthukumar Gomathi, Ziegler, Slava, Pahl, Axel, Sievers, Sonja, Kumar, Kamal

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Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor von Laraia, Luca, Garivet, Guillaume, Foley, Daniel J., Kaiser, Nadine, Müller, Sebastian, Zinken, Sarah, Pinkert, Thomas, Wilke, Julian, Corkery, Dale, Pahl, Axel, Sievers, Sonja, Janning, Petra, Arenz, Christoph, Wu, Yaowen, Rodriguez, Raphaël, Waldmann, Herbert

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Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas von Götze, Silke, Wolter, Marietta, Reifenberger, Guido, Müller, Oliver, Sievers, Sonja

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Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization von Hackl, Mathias W, Lakemeyer, Markus, Dahmen, Maria, Glaser, Manuel, Pahl, Axel, Lorenz-Baath, Katrin, Menzel, Thomas, Sievers, Sonja, Böttcher, Thomas, Antes, Iris, Waldmann, Herbert, Sieber, Stephan A

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The Organocatalytic Approach to Enantiopure 2H- and 3H-Pyrroles: Inhibitors of the Hedgehog Signaling Pathway von Kötzner, Lisa, Leutzsch, Markus, Sievers, Sonja, Patil, Sumersing, Waldmann, Herbert, Zheng, Yiying, Thiel, Walter, List, Benjamin

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Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway von Samanta, Rajarshi, Narayan, Rishikesh, Bauer, Jonathan O, Strohmann, Carsten, Sievers, Sonja, Antonchick, Andrey P

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Small-molecule screening of ribonuclease L binders for RNA degradation von Borgelt, Lydia, Haacke, Neele, Lampe, Philipp, Qiu, Xiaqiu, Gasper, Raphael, Schiller, Damian, Hwang, Jimin, Sievers, Sonja, Wu, Peng

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ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma von Götze, Silke, Feldhaus, Valeska, Traska, Thilo, Wolter, Marietta, Reifenberger, Guido, Tannapfel, Andrea, Kuhnen, Cornelius, Martin, Dirk, Müller, Oliver, Sievers, Sonja

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Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells von GÖTZE, SILKE, COERSMEYER, MONIQUE, MÜLLER, OLIVER, SIEVERS, SONJA

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Synthesis of Indofulvin Pseudo‐Natural Products Yields a New Autophagy Inhibitor Chemotype von Burhop, Annina, Bag, Sukdev, Grigalunas, Michael, Woitalla, Sophie, Bodenbinder, Pia, Brieger, Lukas, Strohmann, Carsten, Pahl, Axel, Sievers, Sonja, Waldmann, Herbert

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2‐Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation von Förster, Tim, Shang, Erchang, Shimizu, Kenshiro, Sanada, Emiko, Schölermann, Beate, Huebecker, Mylene, Hahne, Gernot, López‐Alberca, Maria Pascual, Janning, Petra, Watanabe, Nobumoto, Sievers, Sonja, Giordanetto, Fabrizio, Shimizu, Takeshi, Ziegler, Slava, Osada, Hiroyuki, Waldmann, Herbert

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Discovery of a Novel Pseudo‐Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling von Wang, Lin, Yilmaz, Furkan, Yildirim, Okan, Schölermann, Beate, Bag, Sukdev, Greiner, Luca, Pahl, Axel, Sievers, Sonja, Scheel, Rebecca, Strohmann, Carsten, Squire, Christopher, Foley, Daniel J., Ziegler, Slava, Grigalunas, Michael, Waldmann, Herbert

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Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation von Sidarovich, Anzhalika, Will, Cindy L, Anokhina, Maria M, Ceballos, Javier, Sievers, Sonja, Agafonov, Dmitry E, Samatov, Timur, Bao, Penghui, Kastner, Berthold, Urlaub, Henning, Waldmann, Herbert, Lührmann, Reinhard

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Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma von Shamloo, Sama, Kloetgen, Andreas, Petroulia, Stavroula, Hockemeyer, Kathryn, Sievers, Sonja, Tsirigos, Aristotelis, Aifantis, Ioannis, Imig, Jochen

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Morphological profiling of small molecules von Ziegler, Slava, Sievers, Sonja, Waldmann, Herbert

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The Cell Painting Assay as a Screening Tool for the Discovery of Bioactivities in New Chemical Matter von Pahl, Axel, Sievers, Sonja

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Fluorescent probes and degraders of the sterol transport protein Aster-A von He, Nianzhe, Depta, Laura, Sievers, Sonja, Laraia, Luca

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