RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks von Dungrawala, Huzefa, Bhat, Kamakoti P., Le Meur, Rémy, Chazin, Walter J., Ding, Xia, Sharan, Shyam K., Wessel, Sarah R., Sathe, Aditya A., Zhao, Runxiang, Cortez, David

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Replication fork stability confers chemoresistance in BRCA-deficient cells von Ray Chaudhuri, Arnab, Callen, Elsa, Ding, Xia, Gogola, Ewa, Duarte, Alexandra A., Lee, Ji-Eun, Wong, Nancy, Lafarga, Vanessa, Calvo, Jennifer A., Panzarino, Nicholas J., John, Sam, Day, Amanda, Crespo, Anna Vidal, Shen, Binghui, Starnes, Linda M., Ruiter, Julian R. de, Daniel, Jeremy A., Konstantinopoulos, Panagiotis A., Cortez, David, Cantor, Sharon B., Fernandez-Capetillo, Oscar, Ge, Kai, Jonkers, Jos, Rottenberg, Sven, Sharan, Shyam K., Nussenzweig, André

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Recombineering: a homologous recombination-based method of genetic engineering von Sharan, Shyam K, Thomason, Lynn C, Kuznetsov, Sergey G, Court, Donald L

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Genetically engineered mouse models for hereditary cancer syndromes von Biswas, Kajal, Mohammed, Altaf, Sharan, Shyam K., Shoemaker, Robert H.

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Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity von Palmer, Nathan, Talib, S Zakiah A, Goh, Christine M F, Biswas, Kajal, Sharan, Shyam K, Kaldis, Philipp

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Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants von Sahu, Sounak, Sullivan, Teresa L, Mitrophanov, Alexander Y, Galloux, Mélissa, Nousome, Darryl, Southon, Eileen, Caylor, Dylan, Mishra, Arun Prakash, Evans, Christine N, Clapp, Michelle E, Burkett, Sandra, Malys, Tyler, Chari, Raj, Biswas, Kajal, Sharan, Shyam K

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Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2 von Hartford, Suzanne A, Chittela, Rajanikant, Ding, Xia, Vyas, Aradhana, Martin, Betty, Burkett, Sandra, Haines, Diana C, Southon, Eileen, Tessarollo, Lino, Sharan, Shyam K

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Translating Embryogenesis to Generate Organoids: Novel Approaches to Personalized Medicine von Sahu, Sounak, Sharan, Shyam K.

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Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect von Singh, Smriti, Narayanan, Sathiya Pandi, Biswas, Kajal, Gupta, Amit, Ahuja, Neha, Yadav, Sandhya, Panday, Rajendra Kumar, Samaiya, Atul, Sharan, Shyam K., Shukla, Sanjeev

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Coiled-Coil Domain: Uncoiling Tumor Suppression by BRCA1 von Mishra, Arun P, Sahu, Sounak, Sharan, Shyam K

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Saturation genome editing-based clinical classification of BRCA2 variants von Sahu, Sounak, Galloux, Melissa, Southon, Eileen, Caylor, Dylan, Sullivan, Teresa, Arnaudi, Matteo, Zanti, Maria, Geh, Josephine, Chari, Raj, Michailidou, Kyriaki, Papaleo, Elena, Sharan, Shyam K

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microRNA-155 positively regulates glucose metabolism via PIK3R1-FOXO3a-cMYC axis in breast cancer von Kim, Sinae, Lee, Eunji, Jung, Jaeyun, Lee, Jong Won, Kim, Hee Jung, Kim, Jisun, Yoo, Hyun ju, Lee, Hee Jin, Chae, Sun Young, Jeon, Sang Min, Son, Byung Ho, Gong, Gyungyup, Sharan, Shyam K, Chang, Suhwan

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Bypass of premature stop codons and generation of functional BRCA2 by exon skipping von Stauffer, Stacey, Biswas, Kajal, Sharan, Shyam K

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RAD52 S346X variant reduces breast cancer risk in BRCA2 mutation carriers von Biswas, Kajal, Sharan, Shyam K.

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WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells von Datta, Arindam, Biswas, Kajal, Sommers, Joshua A., Thompson, Haley, Awate, Sanket, Nicolae, Claudia M., Thakar, Tanay, Moldovan, George-Lucian, Shoemaker, Robert H., Sharan, Shyam K., Brosh, Robert M.

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Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15 von Moro, Ramona N., Biswas, Uddipta, Kharat, Suhas S., Duzanic, Filip D., Das, Prosun, Stavrou, Maria, Raso, Maria C., Freire, Raimundo, Chaudhuri, Arnab Ray, Sharan, Shyam K., Penengo, Lorenza

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Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies von Ding, Xia, Chaudhuri, Arnab Ray, Callen, Elsa, Pang, Yan, Biswas, Kajal, Klarmann, Kimberly D., Martin, Betty K., Burkett, Sandra, Cleveland, Linda, Stauffer, Stacey, Sullivan, Teresa, Dewan, Aashish, Marks, Hanna, Tubbs, Anthony T., Wong, Nancy, Buehler, Eugen, Akagi, Keiko, Martin, Scott E., Keller, Jonathan R., Nussenzweig, André, Sharan, Shyam K.

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The Indenoisoquinoline TOP1 Inhibitors Selectively Target Homologous Recombination-Deficient and Schlafen 11-Positive Cancer Cells and Synergize with Olaparib von Marzi, Laetitia, Szabova, Ludmila, Gordon, Melanie, Weaver Ohler, Zoe, Sharan, Shyam K, Beshiri, Michael L, Etemadi, Moudjib, Murai, Junko, Kelly, Kathleen, Pommier, Yves

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The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation von Xu, Xiaoping, Ni, Kai, He, Yafeng, Ren, Jianke, Sun, Chongkui, Liu, Yie, Aladjem, Mirit I., Burkett, Sandra, Finney, Richard, Ding, Xia, Sharan, Shyam K., Muegge, Kathrin

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Antibacterial Use in Admitted Patients of a Super Speciality Hospital in Western India von Shyam, Sharan, Jaiswal, Sanjay

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