Targeting Receptor-Mediated Transport for Delivery of Biologics Across the Blood-Brain Barrier von Lajoie, Jason M, Shusta, Eric V

Volltext

Blood-Brain Barrier Modulation to Improve Glioma Drug Delivery von Luo, Huilong, Shusta, Eric V

Volltext

Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis von Nishihara, Hideaki, Perriot, Sylvain, Gastfriend, Benjamin D, Steinfort, Marel, Cibien, Celine, Soldati, Sasha, Matsuo, Kinya, Guimbal, Sarah, Mathias, Amandine, Palecek, Sean P, Shusta, Eric V, Pasquier, Renaud Du, Engelhardt, Britta

Volltext

A human three-dimensional neural-perivascular ‘assembloid’ promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology von Wang, Lu, Sievert, David, Clark, Alex E., Lee, Sangmoon, Federman, Hannah, Gastfriend, Benjamin D., Shusta, Eric V., Palecek, Sean P., Carlin, Aaron F., Gleeson, Joseph G.

Volltext

Blood-brain barrier transport of therapeutics via receptor-mediation von Jones, Angela R, Shusta, Eric V

Volltext

Transcriptomic comparison of human and mouse brain microvessels von Song, Hannah W., Foreman, Koji L., Gastfriend, Benjamin D., Kuo, John S., Palecek, Sean P., Shusta, Eric V.

Volltext

Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling von Lian, Xiaojun, Bao, Xiaoping, Al-Ahmad, Abraham, Liu, Jialu, Wu, Yue, Dong, Wentao, Dunn, Kaitlin K., Shusta, Eric V., Palecek, Sean P.

Volltext

An isogenic blood–brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells von Canfield, Scott G., Stebbins, Matthew J., Morales, Bethsymarie Soto, Asai, Shusaku W., Vatine, Gad D., Svendsen, Clive N., Palecek, Sean P., Shusta, Eric V.

Volltext

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells von Lippmann, Ethan S, Azarin, Samira M, Kay, Jennifer E, Nessler, Randy A, Wilson, Hannah K, Al-Ahmad, Abraham, Palecek, Sean P, Shusta, Eric V

Volltext

Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes von Pulido, Robert S., Munji, Roeben N., Chan, Tamara C., Quirk, Clare R., Weiner, Geoffrey A., Weger, Benjamin D., Rossi, Meghan J., Elmsaouri, Sara, Malfavon, Mario, Deng, Aaron, Profaci, Caterina P., Blanchette, Marie, Qian, Tongcheng, Foreman, Koji L., Shusta, Eric V., Gorman, Michael R., Gachon, Frédéric, Leutgeb, Stefan, Daneman, Richard

Volltext

Commentary on human pluripotent stem cell-based blood-brain barrier models von Lippmann, Ethan S, Azarin, Samira M, Palecek, Sean P, Shusta, Eric V

Volltext

Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier von Vatine, Gad D., Al-Ahmad, Abraham, Barriga, Bianca K., Svendsen, Soshana, Salim, Ariel, Garcia, Leslie, Garcia, Veronica J., Ho, Ritchie, Yucer, Nur, Qian, Tongcheng, Lim, Ryan G., Wu, Jie, Thompson, Leslie M., Spivia, Weston R., Chen, Zhaohui, Van Eyk, Jennifer, Palecek, Sean P., Refetoff, Samuel, Shusta, Eric V., Svendsen, Clive N.

Volltext

Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells von Stebbins, Matthew J., Wilson, Hannah K., Canfield, Scott G., Qian, Tongcheng, Palecek, Sean P., Shusta, Eric V.

Volltext

Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells von Gastfriend, Benjamin D, Nishihara, Hideaki, Canfield, Scott G, Foreman, Koji L, Engelhardt, Britta, Palecek, Sean P, Shusta, Eric V

Volltext

Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties von Stebbins, Matthew J, Gastfriend, Benjamin D, Canfield, Scott G, Lee, Ming-Song, Richards, Drew, Faubion, Madeline G, Li, Wan-Ju, Daneman, Richard, Palecek, Sean P, Shusta, Eric V

Volltext

An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons von Canfield, Scott G, Stebbins, Matthew J, Faubion, Madeline G, Gastfriend, Benjamin D, Palecek, Sean P, Shusta, Eric V

Volltext

Modeling the blood–brain barrier: Beyond the endothelial cells von Gastfriend, Benjamin D., Palecek, Sean P., Shusta, Eric V.

Volltext

Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells von Qian, Tongcheng, Maguire, Shaenah E, Canfield, Scott G, Bao, Xiaoping, Olson, William R, Shusta, Eric V, Palecek, Sean P

Volltext

Identification of lamprey variable lymphocyte receptors that target the brain vasculature von Lajoie, Jason M., Katt, Moriah E., Waters, Elizabeth A., Herrin, Brantley R., Shusta, Eric V.

Volltext

In vitro models of the blood-brain barrier: building in physiological complexity von Katt, Moriah E, Shusta, Eric V

Volltext