Formation of geoinformation provision elements of railway networks for logistic transportation management von Kukhar, M A, Kasyanov, V V, Shuldiner, J V, Maliavin, A N, Voronkov, O A

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Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease von Dewey, Frederick E, Gusarova, Viktoria, O’Dushlaine, Colm, Gottesman, Omri, Trejos, Jesus, Hunt, Charleen, Van Hout, Cristopher V, Habegger, Lukas, Buckler, David, Lai, Ka-Man V, Leader, Joseph B, Murray, Michael F, Ritchie, Marylyn D, Kirchner, H. Lester, Ledbetter, David H, Penn, John, Lopez, Alexander, Borecki, Ingrid B, Overton, John D, Reid, Jeffrey G, Carey, David J, Murphy, Andrew J, Yancopoulos, George D, Baras, Aris, Gromada, Jesper, Shuldiner, Alan R

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The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World Implementation von Shuldiner, A R, Relling, M V, Peterson, J F, Hicks, K, Freimuth, R R, Sadee, W, Pereira, N L, Roden, D M, Johnson, J A, Klein, T E

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Clinical case study meets population cohort: identification of a BRCA1 pathogenic founder variant in Orcadians von Kerr, Shona M, Cowan, Emma, Klaric, Lucija, Bell, Christine, O'Sullivan, Dawn, Buchanan, David, Grzymski, Joseph J, van Hout, Cristopher V, Tzoneva, Gannie, Shuldiner, Alan R, Wilson, James F, Miedzybrodzka, Zosia

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The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems von Luzum, JA, Pakyz, RE, Elsey, AR, Haidar, CE, Peterson, JF, Whirl‐Carrillo, M, Handelman, SK, Palmer, K, Pulley, JM, Beller, M, Schildcrout, JS, Field, JR, Weitzel, KW, Cooper‐DeHoff, RM, Cavallari, LH, O'Donnell, PH, Altman, RB, Pereira, N, Ratain, MJ, Roden, DM, Embi, PJ, Sadee, W, Klein, TE, Johnson, JA, Relling, MV, Wang, L, Weinshilboum, RM, Shuldiner, AR, Freimuth, RR

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Meta-analysis of genome-wide association data identifies two loci influencing age at menarche von Stolk, Lisette, Murabito, Joanne M, Rivadeneira, Fernando, Boerwinkle, Eric, Ferrucci, Luigi, Nalls, Michael A, Shuldiner, Alan R, Bandinelli, Stefania, Kiel, Douglas P, Harris, Tamara B, Spector, Tim D, Folsom, Aaron R, Murray, Anna, Lunetta, Kathryn L, Aspelund, Thor, Weedon, Michael N, van Meurs, Joyce, Visser, Jenny A, Garcia, Melissa, Zhuang, Vivian, Gudnason, Vilmundur, Singleton, Andrew, Zhai, Guangju, McArdle, Patrick F, Launer, Lenore J, Soranzo, Nicole, Streeten, Elizabeth A, Hofman, Albert, Demerath, Ellen W, Wilson, Scott G, Estrada, Karol, Uitterlinden, André G, Eiriksdottir, Gudny, Karasik, David, Tanaka, Toshiko, Franceschini, Nora, Perry, John R B, Smith, Albert V, Cherkas, Lynn

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Implementing genomic medicine in the clinic: the future is here von Manolio, Teri A., Chisholm, Rex L., Ozenberger, Brad, Roden, Dan M., Williams, Marc S., Wilson, Richard, Bick, David, Bottinger, Erwin P., Brilliant, Murray H., Eng, Charis, Frazer, Kelly A., Korf, Bruce, Ledbetter, David H., Lupski, James R., Marsh, Clay, Mrazek, David, Murray, Michael F., O’Donnell, Peter H., Rader, Daniel J., Relling, Mary V., Shuldiner, Alan R., Valle, David, Weinshilboum, Richard, Green, Eric D., Ginsburg, Geoffrey S.

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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure von Henry, Albert, Roselli, Carolina, Sveinbjörnsson, Garðar, Fatemifar, Ghazaleh, Hedman, Åsa K., Morley, Michael P., Helgadottir, Anna, Verweij, Niek, Dehghan, Abbas, Almgren, Peter, Andersson, Charlotte, Backman, Joshua D., Biggs, Mary L., Brandimarto, Jeffrey, Buckbinder, Leonard, Carey, David J., Chasman, Daniel I., Chen, Xu, Chung, Jonathan, Cook, James P., Delgado, Graciela E., Denaxas, Spiros, Dörr, Marcus, Dudley, Samuel C., Esko, Tõnu, Finan, Chris, Gottdiener, John S., Gross, Stefan, Guðbjartsson, Daníel F., Gutmann, Rebecca, Haggerty, Christopher M., Hyde, Craig L., Ingelsson, Erik, Jukema, J. Wouter, Kavousi, Maryam, Khaw, Kay-Tee, Kleber, Marcus E., Køber, Lars, Koekemoer, Andrea, Langenberg, Claudia, Lind, Lars, Lotta, Luca A., Luan, Jian’an, März, Winfried, Melander, Olle, Mordi, Ify R., Morgan, Thomas, Morris, Andrew D., Morris, Andrew P., Morrison, Alanna C., Nelson, Christopher P., Niessner, Alexander, Niiranen, Teemu, O’Donoghue, Michelle L., Owens, Anjali T., Parry, Helen M., Perola, Markus, Rice, Kenneth M., Ridker, Paul M., Rotter, Jerome I., Salo, Perttu, Salomaa, Veikko, Smelser, Diane T., Stender, Steen, Stott, David J., Tammesoo, Mari-Liis, Taylor, Kent D., Teder-Laving, Maris, Thorsteinsdottir, Unnur, Torp-Pedersen, Christian, Trompet, Stella, Tyl, Benoit, Uitterlinden, Andre G., Veluchamy, Abirami, Völker, Uwe, Voors, Adriaan A., Wareham, Nicholas J., Waterworth, Dawn, Weiss, Raul, Wiggins, Kerri L., Yerges-Armstrong, Laura M., Yu, Bing, Zannad, Faiez, Zhao, Jing Hua, Hemingway, Harry, McMurray, John J. V., Yang, Jian, Visscher, Peter M., Malarstig, Anders, Holm, Hilma, Sattar, Naveed, Holmes, Michael V., Cappola, Thomas P., Hingorani, Aroon D., Kuchenbaecker, Karoline, Ellinor, Patrick T., Smith, J. Gustav, Vasan, Ramachandran S., Swerdlow, Daniel I., Lumbers, R. Thomas

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Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits von Speliotes, Elizabeth K, Yerges-Armstrong, Laura M, Wu, Jun, Hernaez, Ruben, Kim, Lauren J, Palmer, Cameron D, Gudnason, Vilmundur, Eiriksdottir, Gudny, Garcia, Melissa E, Launer, Lenore J, Nalls, Michael A, Clark, Jeanne M, Mitchell, Braxton D, Shuldiner, Alan R, Butler, Johannah L, Tomas, Marta, Hoffmann, Udo, Hwang, Shih-Jen, Massaro, Joseph M, O'Donnell, Christopher J, Sahani, Dushyant V, Salomaa, Veikko, Schadt, Eric E, Schwartz, Stephen M, Siscovick, David S, Voight, Benjamin F, Carr, J Jeffrey, Feitosa, Mary F, Harris, Tamara B, Fox, Caroline S, Smith, Albert V, Kao, W H Linda, Hirschhorn, Joel N, Borecki, Ingrid B

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Global Pharmacogenomics Within Precision Medicine: Challenges and Opportunities von Chenoweth, Meghan J., Giacomini, Kathleen M., Pirmohamed, Munir, Hill, Susan L., Schaik, Ron H.N., Schwab, Matthias, Shuldiner, Alan R., Relling, Mary V., Tyndale, Rachel F.

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Exome sequencing and characterization of 49,960 individuals in the UK Biobank von Van Hout, Cristopher V., Tachmazidou, Ioanna, Backman, Joshua D., Hoffman, Joshua D., Liu, Daren, Pandey, Ashutosh K., Gonzaga-Jauregui, Claudia, Khalid, Shareef, Ye, Bin, Banerjee, Nilanjana, Li, Alexander H., O’Dushlaine, Colm, Marcketta, Anthony, Staples, Jeffrey, Schurmann, Claudia, Hawes, Alicia, Maxwell, Evan, Barnard, Leland, Lopez, Alexander, Penn, John, Habegger, Lukas, Blumenfeld, Andrew L., Bai, Xiaodong, O’Keeffe, Sean, Yadav, Ashish, Praveen, Kavita, Jones, Marcus, Salerno, William J., Chung, Wendy K., Surakka, Ida, Willer, Cristen J., Hveem, Kristian, Leader, Joseph B., Carey, David J., Ledbetter, David H., Cardon, Lon, Yancopoulos, George D., Economides, Aris, Coppola, Giovanni, Shuldiner, Alan R., Balasubramanian, Suganthi, Cantor, Michael, Nelson, Matthew R., Whittaker, John, Reid, Jeffrey G., Marchini, Jonathan, Overton, John D., Scott, Robert A., Abecasis, Gonçalo R., Yerges-Armstrong, Laura, Baras, Aris

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Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention von Cavallari, Larisa H., Lee, Craig R., Beitelshees, Amber L., Cooper-DeHoff, Rhonda M., Duarte, Julio D., Voora, Deepak, Kimmel, Stephen E., McDonough, Caitrin W., Gong, Yan, Dave, Chintan V., Pratt, Victoria M., Alestock, Tameka D., Anderson, R. David, Alsip, Jorge, Ardati, Amer K., Brott, Brigitta C., Brown, Lawrence, Chumnumwat, Supatat, Clare-Salzler, Michael J., Coons, James C., Denny, Joshua C., Dillon, Chrisly, Elsey, Amanda R., Hamadeh, Issam S., Harada, Shuko, Hillegass, William B., Hines, Lindsay, Horenstein, Richard B., Howell, Lucius A., Jeng, Linda J.B., Kelemen, Mark D., Lee, Yee Ming, Magvanjav, Oyunbileg, Montasser, May, Nelson, David R., Nutescu, Edith A., Nwaba, Devon C., Pakyz, Ruth E., Palmer, Kathleen, Peterson, Josh F., Pollin, Toni I., Quinn, Alison H., Robinson, Shawn W., Schub, Jamie, Skaar, Todd C., Smith, D. Max, Sriramoju, Vindhya B., Starostik, Petr, Stys, Tomasz P., Stevenson, James M., Varunok, Nicholas, Vesely, Mark R., Wake, Dyson T., Weck, Karen E., Weitzel, Kristin W., Wilke, Russell A., Willig, James, Zhao, Richard Y., Kreutz, Rolf P., Stouffer, George A., Empey, Philip E., Limdi, Nita A., Shuldiner, Alan R., Winterstein, Almut G., Johnson, Julie A.

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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis von Vujkovic, Marijana, Keaton, Jacob M., Lynch, Julie A., Miller, Donald R., Zhou, Jin, Tcheandjieu, Catherine, Huffman, Jennifer E., Assimes, Themistocles L., Lorenz, Kimberly, Zhu, Xiang, Hilliard, Austin T., Judy, Renae L., Huang, Jie, Lee, Kyung M., Klarin, Derek, Pyarajan, Saiju, Danesh, John, Melander, Olle, Rasheed, Asif, Mallick, Nadeem H., Hameed, Shahid, Qureshi, Irshad H., Afzal, Muhammad Naeem, Malik, Uzma, Jalal, Anjum, Abbas, Shahid, Sheng, Xin, Gao, Long, Kaestner, Klaus H., Susztak, Katalin, Sun, Yan V., DuVall, Scott L., Cho, Kelly, Lee, Jennifer S., Gaziano, J. Michael, Phillips, Lawrence S., Meigs, James B., Reaven, Peter D., Wilson, Peter W., Edwards, Todd L., Rader, Daniel J., Damrauer, Scott M., O’Donnell, Christopher J., Tsao, Philip S., Chang, Kyong-Mi, Voight, Benjamin F., Saleheen, Danish

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Identification and functional validation of rare coding variants in genes linked to monogenic obesity von Köroğlu, Çiğdem, Traurig, Michael, Muller, Yunhua L., Day, Samantha E., Piaggi, Paolo, Wiedrich, Kim, Vazquez, Laura, Hanson, Robert L., Van Hout, Cristopher V., Alkelai, Anna, Shuldiner, Alan R., Bogardus, Clifton, Baier, Leslie J.

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Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction von O'DONNELL, Christopher J, KAVOUSI, Maryam, HOFFMANN, Udo, BIELAK, Lawrence F, QUNYUAN ZHANG, EIRIKSDOTTIR, Gudny, VAN DUIJN, Cornelia M, FOX, Caroline S, DE ANDRADE, Mariza, KRAJA, Aldi T, SIGURDSSON, Sigurdur, ELIAS-SMALE, Suzette E, SMITH, Albert V, MURABITO, Joanne M, LAUNER, Lenore J, VAN DER LUGT, Aad, KATHIRESAN, Sekar, KRESTIN, Gabriel P, HERRINGTON, David M, HOWARD, Timothy D, YONGMEI LIU, POST, Wendy, MITCHELL, Braxton D, KARDIA, Sharon L. R, O'CONNELL, Jeffrey R, HAIQING SHEN, SHULDINER, Alan R, ALTSHULER, David, ELOSUA, Roberto, SALOMAA, Veikko, SCHWARTZ, Stephen M, SISCOVICK, David S, VOIGHT, Benjamin F, BIS, Joshua C, FEITOSA, Mary F, GLAZER, Nicole L, PSATY, Bruce M, BOERWINKLE, Eric, HEISS, Gerardo, BLANKENBERG, Stefan, ZELLER, Tanja, WILD, Philipp S, SCHNABEL, Renate B, SCHILLERT, Arne, ZIEGLER, Andreas, HWANG, Shih-Jen, MIINZEL, Thomas F, WHITE, Charles C, ROTTER, Jerome I, NAILS, Michael, OUDKERK, Matthijs, JOHNSON, Andrew D, NEWMAN, Anne B, UITTERLINDEN, Andre G, MASSARO, Joseph M, CUNNINGHAM, Julie, SUN, Yan V, PROVINCE, Michael A, ASPELUND, Thor, DEHGHAN, Abbas

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The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response von Giacomini, K M, Brett, C M, Altman, R B, Benowitz, N L, Dolan, M E, Flockhart, D A, Johnson, J A, Hayes, D F, Klein, T, Krauss, R M, Kroetz, D L, McLeod, H L, Nguyen, A T, Ratain, M J, Relling, M V, Reus, V, Roden, D M, Schaefer, C A, Shuldiner, A R, Skaar, T, Tantisira, K, Tyndale, R F, Wang, L, Weinshilboum, R M, Weiss, S T, Zineh, I

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Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation von Chu, Audrey Y, Deng, Xuan, Fisher, Virginia A, Drong, Alexander, Zhang, Yang, Feitosa, Mary F, Liu, Ching-Ti, Weeks, Olivia, Choh, Audrey C, Duan, Qing, Dyer, Thomas D, Eicher, John D, Guo, Xiuqing, Heard-Costa, Nancy L, Kacprowski, Tim, Kent, Jack W, Lange, Leslie A, Liu, Xinggang, Lohman, Kurt, Lu, Lingyi, Mahajan, Anubha, O'Connell, Jeffrey R, Parihar, Ankita, Peralta, Juan M, Smith, Albert V, Zhang, Yi, Homuth, Georg, Kissebah, Ahmed H, Kullberg, Joel, Laqua, René, Launer, Lenore J, Nauck, Matthias, Olivier, Michael, Peyser, Patricia A, Terry, James G, Wojczynski, Mary K, Yao, Jie, Bielak, Lawrence F, Blangero, John, Borecki, Ingrid B, Bowden, Donald W, Carr, John Jeffrey, Czerwinski, Stefan A, Ding, Jingzhong, Friedrich, Nele, Gudnason, Vilmunder, Harris, Tamara B, Ingelsson, Erik, Johnson, Andrew D, Kardia, Sharon L R, Langefeld, Carl D, Lind, Lars, Liu, Yongmei, Mitchell, Braxton D, Morris, Andrew P, Mosley, Thomas H, Rotter, Jerome I, Shuldiner, Alan R, Towne, Bradford, Völzke, Henry, Wallaschofski, Henri, Wilson, James G, Allison, Matthew, Lindgren, Cecilia M, Goessling, Wolfram, Cupples, L Adrienne, Steinhauser, Matthew L, Fox, Caroline S

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Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR Study von Dewey, Frederick E.

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Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity von Akbari, Parsa, Gilani, Ankit, Sosina, Olukayode, Kosmicki, Jack A., Khrimian, Lori, Fang, Yi-Ya, Persaud, Trikaldarshi, Garcia, Victor, Sun, Dylan, Li, Alexander, Mbatchou, Joelle, Locke, Adam E., Benner, Christian, Verweij, Niek, Lin, Nan, Hossain, Sakib, Agostinucci, Kevin, Pascale, Jonathan, Dirice, Ercument, Dunn, Michael, Kraus, William E., Shah, Svati H., Chen, Yii-Der, Rotter, Jerome, Rader, Daniel J., Melander, Olle, Still, Christopher D., Mirshahi, Tooraj, Carey, David J., Berumen-Campos, Jaime, Kuri-Morales, Pablo, Alegre-Diaz, Jesus, Torres, Jason M., Emberson, Jonathan R., Collins, Rory, Balasubramanian, Suganthi, Hawes, Alicia, Jones, Marcus, Zambrowicz, Brian, Murphy, Andrew J., Paulding, Charles, Coppola, Giovanni, Overton, John D., Reid, Jeffrey G., Shuldiner, Alan R., Cantor, Michael, Kang, Hyun M., Abecasis, Goncalo R., Karalis, Katia, Economides, Aris N., Marchini, Jonathan, Yancopoulos, George D., Sleeman, Mark W., Altarejos, Judith, Della Gatta, Giusy, Tapia-Conyer, Roberto, Schwartzman, Michal L., Baras, Aris, Ferreira, Manuel A. R., Lotta, Luca A.

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Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank von Szustakowski, Joseph D., Balasubramanian, Suganthi, Kvikstad, Erika, Khalid, Shareef, Bronson, Paola G., Sasson, Ariella, Wong, Emily, Liu, Daren, Wade Davis, J., Haefliger, Carolina, Katrina Loomis, A., Mikkilineni, Rajesh, Noh, Hyun Ji, Wadhawan, Samir, Bai, Xiaodong, Hawes, Alicia, Krasheninina, Olga, Ulloa, Ricardo, Lopez, Alex E., Smith, Erin N., Waring, Jeffrey F., Whelan, Christopher D., Tsai, Ellen A., Overton, John D., Salerno, William J., Jacob, Howard, Szalma, Sandor, Runz, Heiko, Hinkle, Gregory, Nioi, Paul, Petrovski, Slavé, Miller, Melissa R., Baras, Aris, Mitnaul, Lyndon J., Reid, Jeffrey G.

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