Discovering Anti-Cancer Drugs via Computational Methods von Cui, Wenqiang, Aouidate, Adnane, Wang, Shouguo, Yu, Qiuliyang, Li, Yanhua, Yuan, Shuguang

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New Binding Sites, New Opportunities for GPCR Drug Discovery von Chan, H.C. Stephen, Li, Yi, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang

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Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers von Zhang, Yingyi, Dijkman, Patricia M., Zou, Rongfeng, Zandl-Lang, Martina, Sanchez, Ricardo M., Eckhardt-Strelau, Luise, Köfeler, Harald, Vogel, Horst, Yuan, Shuguang, Kudryashev, Mikhail

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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis von Han, Yachun, Xu, Xiaoxuan, Tang, Chengyuan, Gao, Peng, Chen, Xianghui, Xiong, Xiaofen, Yang, Ming, Yang, Shikun, Zhu, Xuejing, Yuan, Shuguang, Liu, Fuyou, Xiao, Li, Kanwar, Yashpal S., Sun, Lin

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Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures von Hua, Tian, Li, Xiaoting, Wu, Lijie, Iliopoulos-Tsoutsouvas, Christos, Wang, Yuxia, Wu, Meng, Shen, Ling, Brust, Christina A., Nikas, Spyros P., Song, Feng, Song, Xiyong, Yuan, Shuguang, Sun, Qianqian, Wu, Yiran, Jiang, Shan, Grim, Travis W., Benchama, Othman, Stahl, Edward L., Zvonok, Nikolai, Zhao, Suwen, Bohn, Laura M., Makriyannis, Alexandros, Liu, Zhi-Jie

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Structure-Guided Rational Design of a Mono- and Diacylglycerol Lipase from Aspergillus oryzae: A Single Residue Mutant Increases the Hydrolysis Ability von Lan, Dongming, Zhao, Ge, Holzmann, Nicole, Yuan, Shuguang, Wang, Jia, Wang, Yonghua

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MM/PB(GB)SA benchmarks on soluble proteins and membrane proteins von Wang, Shiyu, Sun, Xiaolin, Cui, Wenqiang, Yuan, Shuguang

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TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease von Wang, Youliang, Zhu, Xuejing, Yuan, Shuguang, Wen, Si, Liu, Xuemei, Wang, Chang, Qu, Zhong, Li, Jun, Liu, Hong, Sun, Lin, Liu, Fuyou

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Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase von Xia, Yao, Zou, Rongfeng, Escouboué, Maxime, Zhong, Liang, Zhu, Chengjun, Pouzet, Cécile, Wu, Xueqiang, Wang, Yongjin, Lv, Guohua, Zhou, Haibo, Sun, Pinghua, Ding, Ke, Deslandes, Laurent, Yuan, Shuguang, Zhang, Zhi-Min

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The Role of TLR4 on PGC-1α-Mediated Oxidative Stress in Tubular Cell in Diabetic Kidney Disease von Sun, Lin, Liu, Fuyou, Liu, Hong, Xiao, Li, Li, Jun, Gong, Zailiang, Qu, Zhong, Shuguang, Yuan, Liu, Xuemei, Yuan, Shuguang, Yang, Yuan

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Accurate Physical Property Predictions via Deep Learning von Hou, Yuanyuan, Wang, Shiyu, Bai, Bing, Chan, H C Stephen, Yuan, Shuguang

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Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates von Kong, Xu-Dong, Yuan, Shuguang, Li, Lin, Chen, She, Xu, Jian-He, Zhou, Jiahai

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Cryo-EM structure of human heptameric pannexin 2 channel von Zhang, Hang, Wang, Shiyu, Zhang, Zhenzhen, Hou, Mengzhuo, Du, Chunyu, Zhao, Zhenye, Vogel, Horst, Li, Zhifang, Yan, Kaige, Zhang, Xiaokang, Lu, Jianping, Liang, Yujie, Yuan, Shuguang, Wang, Daping, Zhang, Huawei

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High salt promotes autoimmunity by TET2-induced DNA demethylation and driving the differentiation of Tfh cells von Wu, Haijing, Huang, Xin, Qiu, Hong, Zhao, Ming, Liao, Wei, Yuan, Shuguang, Xie, Yubing, Dai, Yong, Chang, Christopher, Yoshimura, Akihiko, Lu, Qianjin

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Predictive value of sub classification of focal segmental glomerular sclerosis in Oxford classification of IgA nephropathy von Yu, Fang, Zhu, Xuejing, Yuan, Shuguang, Chen, Xiaojun, Li, Zheng, Qu, Zhong, Liu, Hong, Sun, Lin, Liu, Fuyou

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MolADI: A Web Server for Automatic Analysis of Protein–Small Molecule Dynamic Interactions von Bai, Bing, Zou, Rongfeng, Chan, H. C. Stephen, Li, Hongchun, Yuan, Shuguang

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Alpha-kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway von Cui, Xinyuan, Li, Yifu, Yuan, Shuguang, Huang, Yao, Chen, Xiaojun, Han, Yachun, Liu, Zhiwen, Li, Zheng, Xiao, Yang, Wang, Youliang, Sun, Lin, Liu, Hong, Zhu, Xuejing

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p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy von Xu, Xiaoxuan, Zhu, Xuejing, Ma, Mingming, Han, Yachun, Hu, Chun, Yuan, Shuguang, Yang, Yuan, Xiao, Li, Liu, Fuyou, Kanwar, Yashpal S., Sun, Lin

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Tubular atrophy/interstitial fibrosis scores of Oxford classification combinded with proteinuria level at biopsy provides earlier risk prediction in lgA nephropathy von Zhu, Xuejing, Li, Huiqiong, Liu, Yexin, You, Jing, Qu, Zhong, Yuan, Shuguang, Peng, Youming, Liu, Fuyou, Liu, Hong

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Bowman's capsule rupture and the Oxford MEST-C score in adult patients with Immunoglobulin a vasculitis nephritis: a single center experience von Zhao, Qing, Duan, Tongyue, Chen, Anqun, He, Liyu, Liu, Hong, Yuan, Shuguang, Tang, Chengyuan, Liu, Yinghong, Liu, Yu, Liu, Fuyou, Xiao, Li, Zhu, Xuejing, Sun, Lin

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