Patient understanding of pharmacogenomic test results in clinical care von Doyle, Tom A., Schmidt, Karen K., Halverson, Colin M.E., Olivera, Jesus, Garcia, Abigail, Shugg, Tyler A., Skaar, Todd C., Schwartz, Peter H.

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Abstract 12367: Inhibition of Outward Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestolol von Shugg, Tyler A, Somberg, John C, Molnar, Janos, Overholser, Brian R

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Zwitterionic Chitosan Derivatives for pH-Sensitive Stealth Coating von Xu, Peisheng, Bajaj, Gaurav, Shugg, Tyler, Van Alstine, William G, Yeo, Yoon

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Neurohormonal Regulation of IKs in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death von Shugg, Tyler, Hudmon, Andy, Overholser, Brian R

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Prevalence and types of inconsistencies in clinical pharmacogenetic recommendations among major U.S. sources von Shugg, Tyler, Pasternak, Amy L., London, Bianca, Luzum, Jasmine A.

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Functional analysis of G6PD variants associated with low G6PD activity in the All of Us Research Program von Powell, Nicholas R, Geck, Renee C, Lai, Dongbing, Shugg, Tyler, Skaar, Todd C, Dunham, Maitreya J

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PCCA variant rs16957301 is a novel AKI risk genotype-specific for patients who receive ICI treatment: Real-world evidence from all of us cohort von Wang, Yanfei, Xiong, Chenxi, Yu, Weifeng, Zhou, Minghao, Shugg, Tyler, Hsu, Fang-Chi, Eadon, Michael T., Su, Jing, Song, Qianqian

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Neurohormonal Regulation of I Ks in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death von Shugg, Tyler, Hudmon, Andy, Overholser, Brian R

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Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report von Powell, Nicholas R, Shugg, Tyler, Ly, Reynold C, Albany, Costantine, Radovich, Milan, Schneider, Bryan P, Skaar, Todd C

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Evaluation of US Food and Drug Administration Drug Label Recommendations for Coadministration of Antivirals and Acid‐Reducing Agents von Shugg, Tyler, Powell, Nicholas R., Marroum, Patrick J., Skaar, Todd C., Younis, Islam R.

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Computational pharmacogenotype extraction from clinical next-generation sequencing von Shugg, Tyler, Ly, Reynold C, Osei, Wilberforce, Rowe, Elizabeth J, Granfield, Caitlin A, Lynnes, Ty C, Medeiros, Elizabeth B, Hodge, Jennelle C, Breman, Amy M, Schneider, Bryan P, Sahinalp, S Cenk, Numanagić, Ibrahim, Salisbury, Benjamin A, Bray, Steven M, Ratcliff, Ryan, Skaar, Todd C

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Implementation of Clinical Cytochrome P450 3A Genotyping for Tacrolimus Dosing in a Large Kidney Transplant Program von Tillman, Emma, Nikirk, Miley G., Chen, Jeanne, Skaar, Todd C., Shugg, Tyler, Maddatu, Judith P., Sharfuddin, Asif A., Eadon, Michael T.

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Analysis of the combined effect of rs699 and rs5051 on angiotensinogen expression and hypertension von Powell, Nicholas R., Shugg, Tyler, Leighty, Jacob, Martin, Matthew, Kreutz, Rolf P., Eadon, Michael T., Lai, Dongbing, Lu, Tao, Skaar, Todd C.

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Development of a Multifaceted Program for Pharmacogenetics Adoption at an Academic Medical Center: Practical Considerations and Lessons Learned von Shugg, Tyler, Tillman, Emma M., Breman, Amy M., Hodge, Jennelle C., McDonald, Christine A., Ly, Reynold C., Rowe, Elizabeth J., Osei, Wilberforce, Smith, Tayler B., Schwartz, Peter H., Callaghan, John T., Pratt, Victoria M., Lynch, Sheryl, Eadon, Michael T., Skaar, Todd C.

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eP373: Analytical validation of a computational method for pharmacogenetic genotyping from clinical exome sequencing von Ly, Reynold, Shugg, Tyler, Ratcliff, Ryan, Osei, Wilberforce, Pratt, Victoria, Schneider, Bryan, Radovich, Milan, Bray, Steven, Salisbury, Benjamin, Parikh, Baiju, Sahinalp, S. Cenk, Numanagić, Ibrahim, Skaar, Todd

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Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure von Luzum, Jasmine A., Ting, Christopher, Peterson, Edward L., Gui, Hongsheng, Shugg, Tyler, Williams, L. Keoki, Li, Liang, Sadee, Wolfgang, Wang, Danxin, Lanfear, David E.

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Letrozole targets the human ether‐a‐go‐go–related gene potassium current in glioblastoma von Shugg, Tyler, Dave, Nimita, Amarh, Enoch, Assiri, Abdullah A., Pollok, Karen E., Overholser, Brian R.

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Progesterone Metabolites Inhibit the Human Ether‐a‐go‐go‐Related Gene and Predict QT Interval Length von Shugg, Tyler, Egly, Christian, Stamatkin, Chris W., Patil, Avinash S., Tisdale, James E., Overholser, Brian R.

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Analytical Validation of a Computational Method for Pharmacogenetic Genotyping from Clinical Whole Exome Sequencing von Ly, Reynold C., Shugg, Tyler, Ratcliff, Ryan, Osei, Wilberforce, Lynnes, Ty C., Pratt, Victoria M., Schneider, Bryan P., Radovich, Milan, Bray, Steven M., Salisbury, Benjamin A., Parikh, Baiju, Sahinalp, S. Cenk, Numanagić, Ibrahim, Skaar, Todd C.

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Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B666 Allele Carriers von ABDELHADY, AHMED M., SHUGG, TYLER, THONG, NANCY, LU, JESSICA BO LI, KREUTZ, YVONNE, JAYNES, HEATHER A., ROBARGE, JASON D., TISDALE, JAMES E., DESTA, ZERUESENAY, OVERHOLSER, BRIAN R.

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