Creating transient cell membrane pores using a standard inkjet printer von Owczarczak, Alexander B, Shuford, Stephen O, Wood, Scott T, Deitch, Sandra, Dean, Delphine

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Abstract 2244: PARP inhibition in combination with pembrolizumab enhances cytotoxicity in ovarian cancer patient-derived 3D spheroids von Appleton, Kathryn M., Elrod, Ashley, Shuford, Stephen, DesRochers, Teresa M.

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PD-1/PD-L1 checkpoint inhibitors in combination with olaparib display antitumor activity in ovarian cancer patient-derived three-dimensional spheroid cultures von Appleton, Kathryn M., Elrod, Ashley K., Lassahn, Katy A., Shuford, Stephen, Holmes, Lillia M., DesRochers, Teresa M.

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TMOD-42. PROSPECTIVE VALIDATION OF AN EX VIVO 3D ASSAY FOR PREDICTION OF TEMOZOLOMIDE RESPONSE IN GLIOBLASTOMA von Smith, Ashley, Holmes, Lillia, Shuford, Stephen, Kanos, Charles, Gardner, Stephen, Hodge, Philip, Lynn, Michael, Edenfield, Jeff, DesRochers, Teresa

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Prospective Validation of an Ex Vivo, Patient-Derived 3D Spheroid Model for Response Predictions in Newly Diagnosed Ovarian Cancer von Shuford, Stephen, Wilhelm, Christine, Rayner, Melissa, Elrod, Ashley, Millard, Melissa, Mattingly, Christina, Lotstein, Alina, Smith, Ashley M., Guo, Qi Jin, O’Donnell, Lauren, Elder, Jeffrey, Puls, Larry, Weroha, S. John, Hou, Xiaonan, Zanfagnin, Valentina, Nick, Alpa, Stany, Michael P., Maxwell, G. Larry, Conrads, Thomas, Sood, Anil K., Orr, David, Holmes, Lillia M., Gevaert, Matthew, Crosswell, Howland E., DesRochers, Teresa M.

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Abstract 2240: Redefining personalized medicine by drug response profiling of patient-derived spheroids von Shuford, Stephen, Wilhelm, Christine, Smith, Ashley M., Rayner, Melissa, Stuart, Jeremy, Holmes, Lillia, Gevaert, Matt, Crosswell, Howland E., DesRochers, Teresa M.

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Abstract TMIM-069: PROSPECTIVE CLINICAL VALIDATION OF EX VIVO, PATIENT-SPECIFIC RESPONSE PREDICTION TO FIRST-LINE CHEMOTHERAPY von Shuford, Stephen, Elder, Jeffrey, Puls, Larry, Weroha, John, Hou, Xiaonan, Zanfagnin, Valentina, Nick, Alpa, Stany, Michael P., Maxwell, Larry, Conrads, Thomas, Corless, Chris, Sood, Anil K., Gevaert, Matthew, Crosswell, Howland E., DesRochers, Teresa M.

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Abstract 4834: 3D modeling of immune cell interactions in breast cancer and prediction of immunotherapy response von Guo, Qi, Shuford, Stephen, McKinley, Brian, Rippon, Mary, Cornett, Wendy, O'Rourke, Mark, Schammel, David, Edenfield, Jeff, Kaplan, David L., Crosswell, Hal E., Desrochers, Teresa

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Abstract 3935: A perfused 3D co-culture model of vemurafenib-resistant melanoma von Cheluvaraju, Chaitra, Shuford, Stephen, Mattingly, Christina, DesRochers, Teresa, Gevaert, Matthew, Orr, David E., Crosswell, Hal E.

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Abstract 5119: Complex, 3D tissues for modeling the immune response in cancer and predicting the activity of immunotherapies von DesRochers, Tessa M., Holmes, Lillia, Guo, Qi, O’Donnell, Lauren, Shuford, Stephen, Puls, Larry, Elder, Jeff, Edenfield, Jeff, Crosswell, Hal E.

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A Long-term Co-perfused Disseminated Tuberculosis-3D Liver Hollow Fiber Model for Both Drug Efficacy and Hepatotoxicity in Babies von Srivastava, Shashikant, Pasipanodya, Jotam G., Ramachandran, Geetha, Deshpande, Devyani, Shuford, Stephen, Crosswell, Howland E., Cirrincione, Kayle N., Sherman, Carleton M., Swaminathan, Soumya, Gumbo, Tawanda

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Abstract LB-36: Chemotherapy testing of primary human ovarian cancers in an ex vivo 3D culture platform: A novel method of phenotypic profiling for clinical trial selection and per... von Shuford, Stephen, Widener, Rebecca, Cheluvaraju, Chaitra, Desrochers, Teresa, mattingly, christina, Puls, Larry, gevaert, matt, Orr, David, Crosswell, Hal E.

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Abstract 318: Enhancing drug discovery and development throughput without sacrificing predictivity: ex vivo 3D drug response profiling (DRP) using patient-derived xenografts (PDX) von DesRochers, Tessa M., Mattingly, Christina, Shuford, Stephen, Gevaert, Matthew, Orr, David, Bult, Carol, Airhart, Susie, Cheng, Mingshan, Wang, Minan, Keck, James, Crosswell, Howland

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Abstract 320: Perfused 3D tri-culture breast cancer microtumors for accurate prediction of drug response von DesRochers, Tessa M., Shuford, Stephen, Mattingly, Christina, Bruce, Terri, Liu, Zhiyi, Quinn, Kyle, Georgakoudi, Irene, Kaplan, David L., Orr, David, Crosswell, Howland E.

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Abstract LB-282: Ex vivo 3d drug response profiling of primary human ovarian cancer differentiates treatment-naive and relapsed patients and molecular subtypes von Desrochers, Tessa, Shuford, Stephen, Mattingly, Christina, Holmes, Lillia, Gevaert, Matt, Elder, Jeff, Orr, David, Corless, Christopher, Puls, Larry, Crosswell, Hal E.

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Abstract A40: Development of a perfusion-based 3D human tri-culture breast microtumor von DesRochers, Teresa M., Shuford, Stephen, Bruce, Terri F., Gevaert, Matthew R., Cheluvaraju, Chaitra, Georgakoudi, Irene, Kaplan, David L., Orr, Davie E., Crosswell, Howland E.

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Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay von Shuford, Stephen, Lipinski, Lindsay, Abad, Ajay, Smith, Ashley M, Rayner, Melissa, O’Donnell, Lauren, Stuart, Jeremy, Mechtler, Laszlo L, Fabiano, Andrew J, Edenfield, Jeff, Kanos, Charles, Gardner, Stephen, Hodge, Philip, Lynn, Michael, Butowski, Nicholas A, Han, Seunggu J, Redjal, Navid, Crosswell, Howland E, Vibat, Cecile Rose T, Holmes, Lillia, Gevaert, Matthew, Fenstermaker, Robert A, DesRochers, Teresa M

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Abstract 1102: The 3DKUBE™ segregated co-culture system: optimal tumor-stromal interactions for modeling the tumor microenvironment in anticancer therapeutic development von Crosswell, Hal, Widener, Rebecca D., Desgupta, Anindya, Shuford, Stephen, Gevaert, Matthew R., Orr, David E., Langenheim, John

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Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer von Owczarczak, Alexander B., Shuford, Stephen O., Wood, Scott T., Deitch, Sandra, Dean, Delphine

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Macrophage incorporation into a 3D perfusion tri-culture model of human breast cancer von DesRochers, Teresa M, Holmes, Lillia, O'Donnell, Lauren, Mattingly, Christina, Shuford, Stephen, O'Rourke, Mark A, Rippon, Mary B, Edenfield, William J, Gevaert, Matthew R, Orr, David E, Crosswell, Howland E

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