Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids von Hu, Ming-Ming, Shu, Hong-Bing

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The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation von Lin, Heng, Li, Shu, Shu, Hong-Bing

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DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity von Sun, Xiaona, Liu, Ting, Zhao, Jun, Xia, Hansong, Xie, Jun, Guo, Yu, Zhong, Li, Li, Mi, Yang, Qing, Peng, Cheng, Rouvet, Isabelle, Belot, Alexandre, Shu, Hong-Bing, Feng, Pinghui, Zhang, Junjie

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Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response von Li, Mi, Shu, Hong-Bing

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Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination von Wu, Xin, Lei, Caoqi, Xia, Tian, Zhong, Xuan, Yang, Qing, Shu, Hong-Bing

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Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5 von Hu, Ming-Ming, Liao, Chen-Yang, Yang, Qing, Xie, Xue-Qin, Shu, Hong-Bing

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The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors von Lian, Huan, Zang, Ru, Wei, Jin, Ye, Wen, Hu, Ming-Ming, Chen, Yun-Da, Zhang, Xia-Nan, Guo, Yi, Lei, Cao-Qi, Yang, Qing, Luo, Wei-Wei, Li, Shu, Shu, Hong-Bing

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Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus von Hu, Ming-Ming, Yang, Qing, Xie, Xue-Qin, Liao, Chen-Yang, Lin, Heng, Liu, Tian-Tian, Yin, Lei, Shu, Hong-Bing

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ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response von Lian, Huan, Wei, Jin, Zang, Ru, Ye, Wen, Yang, Qing, Zhang, Xia-Nan, Chen, Yun-Da, Fu, Yu-Zhi, Hu, Ming-Ming, Lei, Cao-Qi, Luo, Wei-Wei, Li, Shu, Shu, Hong-Bing

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mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis von Liu, Rui, Zeng, Lin-Wen, Gong, Rong, Yuan, Fanen, Shu, Hong-Bing, Li, Shu

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USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy von Xiong, Wenjun, Gao, Xueliang, Zhang, Tiantian, Jiang, Baishan, Hu, Ming-Ming, Bu, Xia, Gao, Yang, Zhang, Lin-Zhou, Xiao, Bo-Lin, He, Chuan, Sun, Yishuang, Li, Haiou, Shi, Jie, Xiao, Xiangling, Xiang, Bolin, Xie, Conghua, Chen, Gang, Zhang, Haojian, Wei, Wenyi, Freeman, Gordon J., Shu, Hong-Bing, Wang, Haizhen, Zhang, Jinfang

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TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination von Zhang, Jing, Hu, Ming-Ming, Wang, Yan-Yi, Shu, Hong-Bing

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USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA von Zhang, Man, Zhang, Meng-Xin, Zhang, Qiang, Zhu, Gao-Feng, Yuan, Lei, Zhang, Dong-Er, Zhu, Qiyun, Yao, Jing, Shu, Hong-Bing, Zhong, Bo

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TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis von Zhang, Hong-Xia, Xu, Zhi-Sheng, Lin, Hen, Li, Mi, Xia, Tian, Cui, Kaisa, Wang, Su-Yun, Li, Youjun, Shu, Hong-Bing, Wang, Yan-Yi

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Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity von Hu, Ming-Ming, He, Wen-Rui, Gao, Peng, Yang, Qing, He, Ke, Cao, Li-Bo, Li, Shu, Feng, Yu-Qi, Shu, Hong-Bing

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The tumor suppressor PTEN has a critical role in antiviral innate immunity von Li, Shun, Zhu, Mingzhu, Pan, Ruangang, Fang, Ting, Cao, Yuan-Yuan, Chen, Shuliang, Zhao, Xiaolu, Lei, Cao-Qi, Guo, Lin, Chen, Yu, Li, Chun-Mei, Jokitalo, Eija, Yin, Yuxin, Shu, Hong-Bing, Guo, Deyin

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USP13 negatively regulates antiviral responses by deubiquitinating STING von Sun, He, Zhang, Qiang, Jing, Ying-Ying, Zhang, Man, Wang, Hai-Ying, Cai, Zeng, Liuyu, Tianzi, Zhang, Zhi-Dong, Xiong, Tian-Chen, Wu, Yan, Zhu, Qi-Yun, Yao, Jing, Shu, Hong-Bing, Lin, Dandan, Zhong, Bo

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Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis von Zhong, Li, Hu, Ming-Ming, Bian, Li-Jun, Liu, Ying, Chen, Qiang, Shu, Hong-Bing

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RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms von Qin, Yue, Zhou, Mao-Tian, Hu, Ming-Ming, Hu, Yun-Hong, Zhang, Jing, Guo, Lin, Zhong, Bo, Shu, Hong-Bing

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TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses von Yang, Qing, Liu, Tian-Tian, Lin, Heng, Zhang, Man, Wei, Jin, Luo, Wei-Wei, Hu, Yun-Hong, Zhong, Bo, Hu, Ming-Ming, Shu, Hong-Bing

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