Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP level in... von Wang, Xuan, Li, Yunsheng, Qian, Yanrong, Cao, Yanyang, Shriwas, Pratik, Zhang, Haiyun, Chen, Xiaozhuo

Volltext

From Transcriptomics, Metabolomics to Functional Studies: Extracellular ATP Induces TGF-β-Like Epithelial Mesenchymal Transition in Lung Cancer Cells von Evers, Maria, Song, Jingwen, Shriwas, Pratik, Greenbaum, Harrison S., Chen, Xiaozhuo

Volltext

A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism von Shriwas, Pratik, Roberts, Dennis, Li, Yunsheng, Wang, Liyi, Qian, Yanrong, Bergmeier, Stephen, Hines, Jennifer, Adhicary, Subhodip, Nielsen, Corinne, Chen, Xiaozhuo

Volltext

Diverse temporal and spatial mechanisms work, partially through Stanniocalcin-1, V-ATPase and senescence, to activate the extracellular ATP-mediated drug resistance in human cancer... von Zhang, Haiyun, Song, Jingwen, Ward, Ryan, Han, Yong, Hunt, Arabella, Shriwas, Pratik, Steed, Alexander, Edwards, Cory, Cao, Yanyang, Co, Milo, Chen, Xiaozhuo

Volltext

Intra-tumoral YAP and TAZ heterogeneity drives collective NSCLC invasion that is targeted by SUMOylation inhibitor TAK-981 von Sharma, Richa, Sharma, Shagun, Shriwas, Pratik, Mehta, Labdhi, Vu, An H., Mouw, Janna K., Koo, Junghui, Huang, Chunzi, Matsuk, Veronika Y., Tucker-Burden, Carol, Joseph, Gregory, Behera, Madhusmita, Sun, Shi-Yong, Roy, Melissa A., Gilbert-Ross, Melissa, Leal, Ticiana, Marcus, Adam I., Shanmugam, Mala

Volltext

Abstract 4191: Characterization of a novel anti-glucose transporter inhibitor as a pan-anticancer therapeutic in vitro and in vivo von Shriwas, Pratik, Bergmeier, Stephen, Chen, Xiaozhuo

Volltext

Plant‐derived glucose transport inhibitors with potential antitumor activity von Shriwas, Pratik, Chen, Xiaozhuo, Kinghorn, A. Douglas, Ren, Yulin

Volltext

First-in-Class Dual Targeting Compounds for the Management of Seizures in Glucose Transporter Type 1 Deficiency Syndrome von Angeli, Andrea, Ferraroni, Marta, Granchi, Carlotta, Minutolo, Filippo, Chen, Xiaozhuo, Shriwas, Pratik, Russo, Emilio, Leo, Antonio, Selleri, Silvia, Carta, Fabrizio, Supuran, Claudiu T.

Volltext

Human CYP2C19 Substrate and Inhibitor Characterization of Organophosphate Pesticides von Vignaux, Patricia A., Shriwas, Pratik, Revnew, Andre, Agarwal, Garima, Lane, Thomas R., McElroy, Craig A., Ekins, Sean

Volltext

Na+/K+‑ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives von Ren, Yulin, Ribas, Hennrique T, Heath, Kimberly, Wu, Sijin, Ren, Jinhong, Shriwas, Pratik, Chen, Xiaozhuo, Johnson, Michael E, Cheng, Xiaolin, Burdette, Joanna E, Kinghorn, A. Douglas

Volltext

Abstract 2799: New-generation glucose transporter inhibitors targeting non-small cell lung cancer and triple-negative breast cancer von Shriwas, Pratik, Qian, Yanrong, Wang, Xuan, Roberts, Dennis, Bergmeier, Stephen, Chen, Xiaozhuo

Volltext

Isosteres of ester derived glucose uptake inhibitors von Roberts, Dennis A., Wang, Liyi, Zhang, Weihe, Liu, Yi, Shriwas, Pratik, Qian, Yanrong, Chen, Xiaozhuo, Bergmeier, Stephen C.

Volltext

Abstract 1157: Screening and identification of new generation glucose transporter inhibitors as anticancer therapeutics von Qian, Yanrong, Shriwas, Pratik, Wang, Xuan, Roberts, Dennis, Kessler, Emma, Bergmeier, Stephen, Chen, Xiaozhuo

Volltext

Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper von Ren, Yulin, Tan, Qingwei, Heath, Kimberly, Wu, Sijin, Wilson, James R., Ren, Jinhong, Shriwas, Pratik, Yuan, Chunhua, Ngoc Ninh, Tran, Chai, Hee-Byung, Chen, Xiaozhuo, Soejarto, Djaja D., Johnson, Michael E., Cheng, Xiaolin, Burdette, Joanna E., Kinghorn, A. Douglas

Volltext

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice von Nielsen, Corinne M., Qian, Yanrong, Adhicary, Subhodip, Li, Yunsheng, Shriwas, Pratik, Wang, Xuan, Bachmann, Lindsey, Chen, Xiaozhuo

Volltext

Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity von Ren, Yulin, Chen, Wei-Lun, Lantvit, Daniel D, Sass, Ellen J, Shriwas, Pratik, Ninh, Tran Ngoc, Chai, Hee-Byung, Zhang, Xiaoli, Soejarto, Djaja D, Chen, Xiaozhuo, Lucas, David M, Swanson, Steven M, Burdette, Joanna E, Kinghorn, A. Douglas

Volltext

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice von Nielsen, Corinne M., Qian, Yanrong, Adhicary, Subhodip, Li, Yunsheng, Shriwas, Pratik, Wang, Xuan, Bachmann, Lindsey, Chen, Xiaozhuo

Volltext

Na+/K+-ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semi-synthetic Derivatives von Ren, Yulin, Ribas, Hennrique T., Heath, Kimberly, Wu, Sijin, Ren, Jinhong, Shriwas, Pratik, Chen, Xiaozhuo, Johnson, Michael E., Cheng, Xiaolin, Burdette, Joanna E., Kinghorn, A. Douglas

Volltext

4‑Amidophenol Quinone Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus-Aged Ac... von Lovins, Alex R., Miller, Kevin A., Buck, Anne K., Ensey, D. Sophia, Homoelle, Rose K., Murtha, Megan C., Ward, Nathan A., Shanahan, Liam A., Gutti, Gopichand, Shriwas, Pratik, McElroy, Craig A., Callam, Christopher S., Hadad, Christopher M.

Volltext

Abstract 1047: Combinatorial anticancer therapy strategy using a pan-class I glucose transporter inhibitor with chemotherapy and target drugs in vitro and in vivo von Bachmann, Lindsey M., Shriwas, Pratik, Ward, Ryan A., Wang, Liyi, Bergmeier, Stephen C., Li, Yunsheng, Chen, Xiaozhuo

Volltext