Progress in the Synthesis of Canthine Alkaloids and Ring-Truncated Congeners von Showalter, H. D. Hollis

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Rifamycins – Obstacles and opportunities von Aristoff, Paul A, Garcia, George A, Kirchhoff, Paul D, Hollis Showalter, H.D

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Quaternary Diamines as Mass Spectrometry Cleavable Crosslinkers for Protein Interactions von Clifford-Nunn, Billy, Showalter, H. D. Hollis, Andrews, Philip C.

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X‑ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins von Molodtsov, Vadim, Nawarathne, Irosha N, Scharf, Nathan T, Kirchhoff, Paul D, Showalter, H. D. Hollis, Garcia, George A, Murakami, Katsuhiko S

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Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423 von Evelyn, Chris R., Bell, Jessica L., Ryu, Jenny G., Wade, Susan M., Kocab, Andrew, Harzdorf, Nicole L., Hollis Showalter, H.D., Neubig, Richard R., Larsen, Scott D.

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Protein cross-linking as a novel mechanism of action of a ubiquitin-activating enzyme inhibitor with anti-tumor activity von Kapuria, Vaibhav, Peterson, Luke F., Showalter, H.D. Hollis, Kirchhoff, Paul D., Talpaz, Moshe, Donato, Nicholas J.

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Stereoselective Synthesis of (S)-3-(Methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile von Lall, Manjinder S, Hoge, Garrett, Tran, Tuan P, Kissel, William, Murphy, Sean T, Taylor, Clarke, Hutchings, Kim, Samas, Brian, Ellsworth, Edmund L, Curran, Timothy, Showalter, H. D. Hollis

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Enediol mimics as inhibitors of the d-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis von Yep, Alejandra, Sorenson, Roderick J., Wilson, Michael R., Hollis Showalter, H.D., Larsen, Scott D., Keller, Paul R., Woodard, Ronald W.

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Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamid... von Smaill, Jeff B, Rewcastle, Gordon W, Loo, Joseph A, Greis, Kenneth D, Chan, O. Helen, Reyner, Eric L, Lipka, Elke, Showalter, H. D. Hollis, Vincent, Patrick W, Elliott, William L, Denny, William A

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Property-based design of a glucosylceramide synthase inhibitor that reduces glucosylceramide in the brain von Larsen, Scott D., Wilson, Michael W., Abe, Akira, Shu, Liming, George, Christopher H., Kirchhoff, Paul, Showalter, H. D. Hollis, Xiang, Jianming, Keep, Richard F., Shayman, James A.

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Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of β-catenin/TCF transcription von Zeller, Jörg, Turbiak, Anjanette J., Powelson, Ian A., Lee, Surin, Sun, Duxin, Showalter, H.D. Hollis, Fearon, Eric R.

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Synthesis and structure–activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors von Titchenell, Paul M., Hollis Showalter, H.D., Pons, Jean-François, Barber, Alistair J., Jin, Yafei, Antonetti, David A.

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3-Aminoquinazolinediones as a New Class of Antibacterial Agents Demonstrating Excellent Antibacterial Activity Against Wild-Type and Multidrug Resistant Organisms von Ellsworth, Edmund L, Tran, Tuan P, Hollis Showalter, H. D, Sanchez, Joseph P, Watson, Brian M, Stier, Michael A, Domagala, John M, Gracheck, Stephen J, Joannides, E. Themis, Shapiro, Martin A, Dunham, Steve A, Hanna, Debra L, Huband, Michael D, Gage, Jeffrey W, Bronstein, Joel C, Liu, Jia Yeu, Nguyen, Dai Q, Singh, Rajeshwar

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Synthesis and structure–activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin von Jin, Yafei, Gill, Sumandeep K., Kirchhoff, Paul D., Wan, Baojie, Franzblau, Scott G., Garcia, George A., Showalter, H.D. Hollis

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A novel synthesis of 3-(substituted)pyrimido[4,5- c]pyridazine-5,7(1 H,6 H)-diones von Turbiak, Anjanette J., Kampf, Jeff W., Hollis Showalter, H.D.

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Synthesis and Structure−Activity Relationships of Soluble 7-Substituted 3-(3,5-Dimethoxyphenyl)-1,6-naphthyridin-2-amines and Related Ureas as Dual Inhibitors of the Fibroblast Gro... von Thompson, Andrew M, Delaney, Amy M, Hamby, James M, Schroeder, Mel C, Spoon, Teresa A, Crean, Sheila M, Showalter, H. D. Hollis, Denny, William A

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3‑Substituted‑N‑(4-Hydroxynaphthalen-1-yl)arylsulfonamides as a Novel Class of Selective Mcl‑1 Inhibitors: Structure-Based Design, Synthesis, SAR, and Biological Evaluation von Abulwerdi, Fardokht A, Liao, Chenzhong, Mady, Ahmed S, Gavin, Jordan, Shen, Chenxi, Cierpicki, Tomasz, Stuckey, Jeanne A, Showalter, H. D. Hollis, Nikolovska-Coleska, Zaneta

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Tyrosine Kinase Inhibitors. 18. 6-Substituted 4-Anilinoquinazolines and 4-Anilinopyrido[3,4-d]pyrimidines as Soluble, Irreversible Inhibitors of the Epidermal Growth Factor Recepto... von Smaill, Jeff B, Showalter, H. D. Hollis, Zhou, Hairong, Bridges, Alexander J, McNamara, Dennis J, Fry, David W, Nelson, James M, Sherwood, Veronika, Vincent, Patrick W, Roberts, Bill J, Elliott, William L, Denny, William A

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Synthesis and structural–activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agents von Tran, Tuan P., Ellsworth, Edmund L., Stier, Michael A., Domagala, John M., Hollis Showalter, H.D., Gracheck, Stephen J., Shapiro, Martin A., Joannides, Themis E., Singh, Rajeshwar

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A 5-week study of the pharmacokinetics and pharmacodynamics of LY2189265, a novel, long-acting glucagon-like peptide-1 analogue, in patients with type 2 diabetes von Barrington, P., Chien, J. Y., Showalter, H. D. H., Schneck, K., Cui, S., Tibaldi, F., Ellis, B., Hardy, T. A.

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