MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death von Prudent, Julien, Zunino, Rodolfo, Sugiura, Ayumu, Mattie, Sevan, Shore, Gordon C., McBride, Heidi M.

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Signaling cell death from the endoplasmic reticulum stress response von Shore, Gordon C, Papa, Feroz R, Oakes, Scott A

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Programming cancer cells for high expression levels of Mcl1 von Ertel, Franziska, Nguyen, Mai, Roulston, Anne, Shore, Gordon C

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Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis von Nguyen, Mai, Marcellus, Richard C, Roulston, Anne, Watson, Mark, Serfass, Lucile, Murthy Madiraju, S.R, Goulet, Daniel, Viallet, Jean, Bélec, Laurent, Billot, Xavier, Acoca, Stephane, Purisima, Enrico, Wiegmans, Adrian, Cluse, Leonie, Johnstone, Ricky W, Beauparlant, Pierre, Shore, Gordon C

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Synergy between the NAMPT inhibitor GMX1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption von Chan, Manuel, Gravel, Michel, Bramoullé, Alexandre, Bridon, Gaëlle, Avizonis, Daina, Shore, Gordon C, Roulston, Anne

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Translation initiation factor eIF4F modifies the dexamethasone response in multiple myeloma von Robert, Francis, Roman, William, Bramoullé, Alexandre, Fellmann, Christof, Roulston, Anne, Shustik, Chaim, Porco, John A., Shore, Gordon C., Sebag, Michael, Pelletier, Jerry

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The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors von Watson, Mark, Roulston, Anne, Bélec, Laurent, Billot, Xavier, Marcellus, Richard, Bédard, Dominique, Bernier, Cynthia, Branchaud, Stéphane, Chan, Helen, Dairi, Kenza, Gilbert, Karine, Goulet, Daniel, Gratton, Michel-Olivier, Isakau, Henady, Jang, Anne, Khadir, Abdelkrim, Koch, Elizabeth, Lavoie, Manon, Lawless, Michael, Nguyen, Mai, Paquette, Denis, Turcotte, Émilie, Berger, Alvin, Mitchell, Matthew, Shore, Gordon C., Beauparlant, Pierre

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Caspase Cleavage Product of BAP31 Induces Mitochondrial Fission through Endoplasmic Reticulum Calcium Signals, Enhancing Cytochrome c Release to the Cytosol von Breckenridge, David G., Stojanovic, Marina, Marcellus, Richard C., Shore, Gordon C.

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New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology von Roulston, Anne, Shore, Gordon C.

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BCL2-CISD2: An ER complex at the nexus of autophagy and calcium homeostasis? von Chang, Natasha C., Nguyen, Mai, Shore, Gordon C.

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Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1 von Chang, Natasha C, Nguyen, Mai, Germain, Marc, Shore, Gordon C

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BH3-only BIK Regulates BAX,BAK-dependent Release of Ca2+ from Endoplasmic Reticulum Stores and Mitochondrial Apoptosis during Stress-induced Cell Death von Mathai, Jaigi P., Germain, Marc, Shore, Gordon C.

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Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy von Cole, Jonathan, Guiot, Marie-Christine, Gravel, Michel, Bernier, Cynthia, Shore, Gordon C, Roulston, Anne

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Antagonism of Beclin 1‐dependent autophagy by BCL‐2 at the endoplasmic reticulum requires NAF‐1 von Chang, Natasha C, Nguyen, Mai, Germain, Marc, Shore, Gordon C

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Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis von Cheung, Eric CC, Joza, Nicholas, Steenaart, Nancy AE, McClellan, Kelly A, Neuspiel, Margaret, McNamara, Stephen, MacLaurin, Jason G, Rippstein, Peter, Park, David S, Shore, Gordon C, McBride, Heidi M, Penninger, Josef M, Slack, Ruth S

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Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31 von Heath-Engel, Hannah M., Wang, Bing, Shore, Gordon C.

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BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization von Ruffolo, Salvatore C, Shore, Gordon C

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BIM, PUMA, and the achilles' heel of oncogene addiction von Roulston, Anne, Muller, William J, Shore, Gordon C

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BH3-ligand regulates access of MCL-1 to its E3 ligase von Warr, Matthew R., Acoca, Stephane, Liu, Zhiqian, Germain, Marc, Watson, Mark, Blanchette, Mathieu, Wing, Simon S., Shore, Gordon C.

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BH-3-only BIK Functions at the Endoplasmic Reticulum to Stimulate Cytochrome c Release from Mitochondria von Germain, Marc, Mathai, Jaigi P., Shore, Gordon C.

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