Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation von Ikizawa, Takeshi, Ikeda, Kazutaka, Arita, Makoto, Kitajima, Shojiro, Soga, Tomoyoshi, Ichijo, Hidenori, Naguro, Isao

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Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization von Kato, Hiroyuki, Asamitsu, Kaori, Sun, Wendi, Kitajima, Shojiro, Yoshizawa-Sugata, Naoko, Okamoto, Takashi, Masai, Hisao, Poellinger, Lorenz

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A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition von Kitajima, Shojiro, Sun, Wendi, Lee, Kian Leong, Ho, Jolene Caifeng, Oyadomari, Seiichi, Okamoto, Takashi, Masai, Hisao, Poellinger, Lorenz, Kato, Hiroyuki

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AGE/RAGE axis regulates reversible transition to quiescent states of ALK-rearranged NSCLC and pancreatic cancer cells in monolayer cultures von Kadonosono, Tetsuya, Miyamoto, Kotaro, Sakai, Shiori, Matsuo, Yoshiyuki, Kitajima, Shojiro, Wang, Qiannan, Endo, Minori, Niibori, Mizuho, Kuchimaru, Takahiro, Soga, Tomoyoshi, Hirota, Kiichi, Kizaka-Kondoh, Shinae

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A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4 von Yamaguchi, Takehiro, Watanabe, Ayano, Tanaka, Masako, Shiota, Masayuki, Osada-Oka, Mayuko, Sano, Soichi, Yoshiyama, Minoru, Miura, Katsuyuki, Kitajima, Shojiro, Matsunaga, Shinji, Tomita, Shuhei, Iwao, Hiroshi, Izumi, Yasukatsu

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Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia von Zhang, Chujing, Amanda, Stella, Wang, Cheng, Tan, Tze King, Ali, Muhammad Zulfaqar, Leong, Wei Zhong, Ng, Ley Moy, Kitajima, Shojiro, Li, Zhenhua, Yeoh, Allen Eng Juh, Tan, Shi Hao, Sanda, Takaomi

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The Hypoxia-Inducible Epigenetic Regulators Jmjd1a and G9a Provide a Mechanistic Link between Angiogenesis and Tumor Growth von Ueda, Jun, Ho, Jolene Caifeng, Lee, Kian Leong, Kitajima, Shojiro, Yang, Henry, Sun, Wendi, Fukuhara, Noriko, Zaiden, Norazean, Chan, Shing Leng, Tachibana, Makoto, Shinkai, Yoichi, Kato, Hiroyuki, Poellinger, Lorenz

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Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer von KUDO, Yasusei, OGAWA, Ikuko, KITAJIMA, Shojiro, KITAGAWA, Masae, KAWAI, Hidehiko, GAFFNEY, Patrick M, MIYAUCHI, Mutsumi, TAKATA, Takashi

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Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression von Sun, Wendi, Kato, Hiroyuki, Kitajima, Shojiro, Lee, Kian Leong, Gradin, Katarina, Okamoto, Takashi, Poellinger, Lorenz

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Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells von Chien, Wenwen, Ding, Ling-Wen, Sun, Qiao-Yang, Torres-Fernandez, Lucia A, Tan, Siew Zhuan, Xiao, Jinfen, Lim, Su Lin, Garg, Manoj, Lee, Kian Leong, Kitajima, Shojiro, Takao, Sumiko, Leong, Wei Zhong, Sun, Haibo, Tokatly, Itay, Poellinger, Lorenz, Gery, Sigal, Koeffler, Phillip H

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Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells von Yamamoto, Takumi, Furukawa, Arisu, Zhou, Yue, Kono, Nobuaki, Kitajima, Shojiro, Ohguchi, Hiroto, Kawano, Yawara, Ito, Shingo, Araki, Norie, Ohtsuki, Sumio, Masuda, Takeshi

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Aurora-B AIM-1 kinase activity is involved in Ras-mediated cell transformation von Kanda, Akifumi, Kawai, Hidehiko, Suto, Shiho, Kitajima, Shojiro, Sato, Sunao, Takata, Takashi, Tatsuka, Masaaki

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Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model von Nishide, Shunji, Matsunaga, Shinji, Shiota, Masayuki, Yamaguchi, Takehiro, Kitajima, Shojiro, Maekawa, Yoichi, Takeda, Norihiko, Tomura, Michio, Uchida, Junji, Miura, Katsuyuki, Nakatani, Tatsuya, Tomita, Shuhei

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Invasion and Metastasis of Oral Cancer Cells Require Methylation of E-Cadherin and/or Degradation of Membranous β-Catenin von KUDO, Yasusei, KITAJIMA, Shojiro, OGAWA, Ikuko, HIRAOKA, Masae, SARGOLZAEI, Soodabeh, KEIKHAEE, Mohammad Reza, SATO, Sunao, MIYAUCHI, Mutsumi, TAKATA, Takashi

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Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis von Tatsuka, Masaaki, Sato, Sunao, Kitajima, Shojiro, Suto, Shiho, Kawai, Hidehiko, Miyauchi, Mutsumi, Ogawa, Ikuko, Maeda, Masayo, Ota, Takahide, Takata, Takashi

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Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model von Nishide, Shunji, Matsunaga, Shinji, Shiota, Masayuki, Yamaguchi, Takehiro, Kitajima, Shojiro, Maekawa, Yoichi, Takeda, Norihiko, Tomura, Michio, Uchida, Junji, Miura, Katsuyuki, Nakatani, Tatsuya, Tomita, Shuhei

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Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer von Kitajima, Shojiro, Kudo, Yasusei, Ogawa, Ikuko, Tatsuka, Masaaki, Kawai, Hidehiko, Pagano, Michele, Takata, Takashi

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Small interfering RNA targeting of S phase kinase–interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation von Kudo, Yasusei, Kitajima, Shojiro, Ogawa, Ikuko, Kitagawa, Masae, Miyauchi, Mutsumi, Takata, Takashi

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Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells von Kitajima, Shojiro, Lee, Kian Leong, Fujioka, Masaki, Sun, Wendi, You, Jia, Chia, Grace Sushin, Wanibuchi, Hideki, Tomita, Shuhei, Araki, Marito, Kato, Hiroyuki, Poellinger, Lorenz

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The noncanonical function of borealin, a component of chromosome passenger complex, promotes glycolysis via stabilization of survivin in squamous cell carcinoma cells von Tawara, Hiroaki, Tsunematsu, Takaaki, Kitajima, Shojiro, Nagao, Ruka, Matsuzawa, Shigefumi, Otsuka, Kunihiro, Ushio, Aya, Ishimaru, Naozumi

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