Dual function of Zika virus NS2B-NS3 protease von Shiryaev, Sergey A, Cieplak, Piotr, Cheltsov, Anton, Liddington, Robert C, Terskikh, Alexey V

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The MMP-9/TIMP-1 axis controls the status of differentiation and function of myelin-forming Schwann cells in nerve regeneration von Kim, Youngsoon, Remacle, Albert G, Chernov, Andrei V, Liu, Huaqing, Shubayev, Igor, Lai, Calvin, Dolkas, Jennifer, Shiryaev, Sergey A, Golubkov, Vladislav S, Mizisin, Andrew P, Strongin, Alex Y, Shubayev, Veronica I

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Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists von Shiryaev, Sergey A., Farhy, Chen, Pinto, Antonella, Huang, Chun-Teng, Simonetti, Nicole, Ngono, Annie Elong, Dewing, Antimone, Shresta, Sujan, Pinkerton, Anthony B., Cieplak, Piotr, Strongin, Alex Y., Terskikh, Alexey V.

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Distinct interactions with cellular E-cadherin of the two virulent metalloproteinases encoded by a Bacteroides fragilis pathogenicity island von Remacle, Albert G, Shiryaev, Sergey A, Strongin, Alex Y

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Zika Virus: Origins, Pathological Action, and Treatment Strategies von Gorshkov, Kirill, Shiryaev, Sergey A, Fertel, Sophie, Lin, Yi-Wen, Huang, Chun-Teng, Pinto, Antonella, Farhy, Chen, Strongin, Alex Y, Zheng, Wei, Terskikh, Alexey V

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Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis von Shiryaev, Sergey A., Mesci, Pinar, Pinto, Antonella, Fernandes, Isabella, Sheets, Nicholas, Shresta, Sujan, Farhy, Chen, Huang, Chun-Teng, Strongin, Alex Y., Muotri, Alysson R., Terskikh, Alexey V.

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Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming von Barile, Elisa, Baggio, Carlo, Gambini, Luca, Shiryaev, Sergey A, Strongin, Alex Y, Pellecchia, Maurizio

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Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors von Li, Hongda, Saucedo-Cuevas, Laura, Yuan, Ling, Ross, Danica, Johansen, Anide, Sands, Daniel, Stanley, Valentina, Guemez-Gamboa, Alicia, Gregor, Anne, Evans, Todd, Chen, Shuibing, Tan, Lei, Molina, Henrik, Sheets, Nicholas, Shiryaev, Sergey A., Terskikh, Alexey V., Gladfelter, Amy S., Shresta, Sujan, Xu, Zhiheng, Gleeson, Joseph G.

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Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis von Shiryaev, Sergey A, Savinov, Alexei Y, Cieplak, Piotr, Ratnikov, Boris I, Motamedchaboki, Khatereh, Smith, Jeffrey W, Strongin, Alex Y

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Matrix Metalloproteinase-14 Both Sheds Cell Surface Neuronal Glial Antigen 2 (NG2) Proteoglycan on Macrophages and Governs the Response to Peripheral Nerve Injury von Nishihara, Tasuku, Remacle, Albert G., Angert, Mila, Shubayev, Igor, Shiryaev, Sergey A., Liu, Huaqing, Dolkas, Jennifer, Chernov, Andrei V., Strongin, Alex Y., Shubayev, Veronica I.

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Allosteric Inhibitors of Zika Virus NS2B-NS3 Protease Targeting Protease in "Super-Open" Conformation von Meewan, Ittipat, Shiryaev, Sergey A, Kattoula, Julius, Huang, Chun-Teng, Lin, Vivian, Chuang, Chiao-Han, Terskikh, Alexey V, Abagyan, Ruben

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Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses von Ladner, Jason T., Henson, Sierra N., Boyle, Annalee S., Engelbrektson, Anna L., Fink, Zane W., Rahee, Fatima, D’ambrozio, Jonathan, Schaecher, Kurt E., Stone, Mars, Dong, Wenjuan, Dadwal, Sanjeet, Yu, Jianhua, Caligiuri, Michael A., Cieplak, Piotr, Bjørås, Magnar, Fenstad, Mona H., Nordbø, Svein A., Kainov, Denis E., Muranaka, Norihito, Chee, Mark S., Shiryaev, Sergey A., Altin, John A.

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High-resolution analysis and functional mapping of cleavage sites and substrate proteins of furin in the human proteome von Shiryaev, Sergey A, Chernov, Andrei V, Golubkov, Vladislav S, Thomsen, Elliot R, Chudin, Eugene, Chee, Mark S, Kozlov, Igor A, Strongin, Alex Y, Cieplak, Piotr

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Immunodominant fragments of myelin basic protein initiate T cell-dependent pain von Liu, Huaqing, Shiryaev, Sergey A, Chernov, Andrei V, Kim, Youngsoon, Shubayev, Igor, Remacle, Albert G, Baranovskaya, Svetlana, Golubkov, Vladislav S, Strongin, Alex Y, Shubayev, Veronica I

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Novel MT1-MMP Small-Molecule Inhibitors Based on Insights into Hemopexin Domain Function in Tumor Growth von REMACLE, Albert G, GOLUBKOV, Vladislav S, SHIRYAEV, Sergey A, DAHL, Russell, STEBBINS, John L, CHERNOV, Andrei V, CHELTSOV, Anton V, PELLECCHIA, Maurizio, STRONGIN, Alex Y

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Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis von Remacle, Albert G, Cieplak, Piotr, Nam, Dong Hyun, Shiryaev, Sergey A, Ge, Xin, Strongin, Alex Y

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New details of HCV NS3/4A proteinase functionality revealed by a high-throughput cleavage assay von Shiryaev, Sergey A, Thomsen, Elliot R, Cieplak, Piotr, Chudin, Eugene, Cheltsov, Anton V, Chee, Mark S, Kozlov, Igor A, Strongin, Alex Y

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Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold von Aleshin, Alexander E., Shiryaev, Sergey A., Strongin, Alex Y., Liddington, Robert C.

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Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry von Yang, Shu, Xu, Miao, Lee, Emily M, Gorshkov, Kirill, Shiryaev, Sergey A., He, Shihua, Sun, Wei, Cheng, Yu-Shan, Hu, Xin, Tharappel, Anil Mathew, Lu, Billy, Pinto, Antonella, Farhy, Chen, Huang, Chun-Teng, Zhang, Zirui, Zhu, Wenjun, Wu, Yuying, Zhou, Yi, Song, Guang, Zhu, Heng, Shamim, Khalida, Martínez-Romero, Carles, García-Sastre, Adolfo, Preston, Richard A., Jayaweera, Dushyantha T., Huang, Ruili, Huang, Wenwei, Xia, Menghang, Simeonov, Anton, Ming, Guoli, Qiu, Xiangguo, Terskikh, Alexey V., Tang, Hengli, Song, Hongjun, Zheng, Wei

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Blocking Zika virus vertical transmission von Mesci, Pinar, Macia, Angela, Moore, Spencer M., Shiryaev, Sergey A., Pinto, Antonella, Huang, Chun-Teng, Tejwani, Leon, Fernandes, Isabella R., Suarez, Nicole A., Kolar, Matthew J., Montefusco, Sandro, Rosenberg, Scott C., Herai, Roberto H., Cugola, Fernanda R., Russo, Fabiele B., Sheets, Nicholas, Saghatelian, Alan, Shresta, Sujan, Momper, Jeremiah D., Siqueira-Neto, Jair L., Corbett, Kevin D., Beltrão-Braga, Patricia C. B., Terskikh, Alexey V., Muotri, Alysson R.

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