Exendin‐4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration von Wang, Y, Parlevliet, E T, Geerling, J J, Tuin, S J L, Zhang, H, Bieghs, V, Jawad, A H M, Shiri‐Sverdlov, R, Bot, I, Jager, S C A, Havekes, L M, Romijn, J A, Willems van Dijk, K, Rensen, P C N

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Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis von Houben, T., Brandsma, E., Walenbergh, S.M.A., Hofker, M.H., Shiri-Sverdlov, R.

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Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity von Wolfs, M G M, Gruben, N, Rensen, S S, Verdam, F J, Greve, J W, Driessen, A, Wijmenga, C, Buurman, W A, Franke, L, Scheja, L, Koonen, D P Y, Shiri-Sverdlov, R, van Haeften, T W, Hofker, M H, Fu, J

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TUB gene expression in hypothalamus and adipose tissue and its association with obesity in humans von Nies, V J M, Struik, D, Wolfs, M G M, Rensen, S S, Szalowska, E, Unmehopa, U A, Fluiter, K, van der Meer, T P, Hajmousa, G, Buurman, W A, Greve, J W, Rezaee, F, Shiri-Sverdlov, R, Vonk, R J, Swaab, D F, Wolffenbuttel, B H R, Jonker, J W, van Vliet-Ostaptchouk, J V

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Low Levels of Natural IGM Antibodies Towards Oxidation-Specific Epitopes are Associated with Human Non-Alcoholic Steatohepatitis von Hendrikx, T, Watzenboeck, M, Walenbergh, S.M, Kalhan, S, Koek, G.H, Jonkers, D, Binder, C.J, Shiri-Sverdlov, R

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Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort von VAN VLIET-OSTAPTCHOUK, J. V, SHIRI-SVERDLOV, R, ZHERNAKOVA, A, STRENGMAN, E, VAN HAEFTEN, T. W, HOFKER, M. H, WIJMENGA, C

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Plasma CETP is derived from hepatic kupffer cells rather than adipose tissue von Blauw, L, de Mutsert, R, Wang, Y, Lamb, H, de Roos, A, Rosendaal, F, Jukema, W, van der Tuin, S, Rensen, S, Shiri-Sverdlov, R, Atanasovska, B, Fu, J, Buurman, W, Greve, J.W, Hofker, M, Willems van Dijk, K, Rensen, P

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O068 : Lysosomal cholesterol in kupffer cells, particularly when oxidized, contributes to murine steatohepatitis von Walenbergh, S, Houben, T, Hendrikx, T, van Gorp, P, Jeurissen, M, Bieghs, V, Lenders, M.-H, Gijbels, M, Plat, J, Hofker, M, Binder, C, Luetjohann, D, Verheyen, F, Koek, G, Shiri-Sverdlov, R

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O067 : Hematopoietic overexpression of CYP27A1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr-/- mice via NPC-modulated cholesterol transport von Hendrikx, T, Jeurissen, M.L, Walenbergh, S.M, Houben, T, van Gorp, P.J, Verheyen, F, Gijbels, M.J, Leitersdorf, E, Hofker, M, Lütjohann, D, Shiri-Sverdlov, R

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Antenatal exposure to chorioamnionitis affects lipid metabolism in 7-week-old sheep von Vlassaks, E., Gavilanes, A. W. D., Bieghs, V., Reinartz, A., Gassler, N., Van Gorp, P. J., Gijbels, M. J. J., Bekers, O., Zimmermann, L. J. I., Pillow, J. J., Polglase, G. R., Nitsos, I., Newnham, J. P., Kallapur, S. G., Jobe, A. H., Shiri-Sverdlov, R., Kramer, B. W.

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1262 HEMATOPOIETIC CASPASE-1 DEFICIENCY REDUCES HEPATIC INFLAMMATION AND CHOLESTEROL CRYSTALLIZATION IN HYPERLIPIDEMIC MICE von Hendrikx, T, Bieghs, V, Walenbergh, S.M, van Gorp, P.J, Verheyen, F, Jeurissen, M.L, Rensen, S.S, Olde Damink, S.W, Buurman, W.A, Greve, J.W, Stienstra, R, Netea, M.G, Hofker, M.H, Shiri-Sverdlov, R

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1306 LYSOSOMAL ENZYMES: A NOVEL NON-INVASIVE APPROACH TO DETECT HEPATIC INFLAMMATION IN NASH von Walenbergh, S.M, Bieghs, V, Hendrikx, T, van Gorp, P.J, Jeurissen, M.L, Verheyen, F, Lindsey, P, Plat, J, Vreugdenhil, A.C, Rensen, S.S, Buurman, W.A, Greve, J.W.M, Koek, G.H, Hofker, M.H, Shiri-Sverdlov, R

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1243 FXR STIMULATION WITH INT-747 IN A RAT BILIARY DRAINAGE MODEL PROTECTS FROM HEPATOCELLULAR INJURY AFTER LOSS OF ENTEROHEPATIC CIRCULATION von Visschers, R.G.J, Koelfat, K.V.K, Hodin, C.M, Lenaerts, K, van Gemert, W.G, Buurman, W.A, Shiri-Sverdlov, R, Mookerjee, R, Olde Damink, S.W.M

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Cathepsin D regulates lipid metabolism in murine steatohepatitis von Houben, Tom, Oligschlaeger, Yvonne, Hendrikx, Tim, Bitorina, Albert V., Walenbergh, Sofie M. A., van Gorp, Patrick J., Gijbels, Marion J. J., Friedrichs, Silvia, Plat, Jogchum, Schaap, Frank G., Lütjohann, Dieter, Hofker, Marten H., Shiri-Sverdlov, Ronit

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P99 FXR stimulation with INT-747 in a rat biliary drainage model protects from hepatocellular injury after loss of enterohepatic circulation von Visschers, R G J, Koelfat, K V K, Hodin, C M, Shiri-Sverdlov, R, Buurman, W A, Mookerjee, R, Lenaerts, K, Damink, S W M O

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P105 Biliary drainage in a rat: a long-term continuous drainage model resulting in liver damage and an altered FXR pathway, lipid and cholesterol metabolism von Koelfat, K V K, Visschers, R G J, Hodin, C M, Shiri-Sverdlov, R, Buurman, W A, Lenaerts, K, Damink, S W M O

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P32 Liver mobilisation during liver resection induces immediate and profound hepatocellular damage and inflammation in humans von van den Broek, M A J, Shiri-Sverdlov, R, Schreurs, J J W, Bloemen, J G, Bieghs, V, Buurman, W A, Dejong, C H C, Olde Damink, S W M

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TUB is a candidate gene for late-onset obesity in women von Snieder, H, Wang, X, Shiri-Sverdlov, R, van Vliet-Ostaptchouk, J. V, Hofker, M. H, Perks, U, Spector, T. D, O'Dell, S. D

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Tumor necrosis factor receptor 1 gain‐of‐function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model von Aparicio‐Vergara, Marcela, Hommelberg, Pascal P.H., Schreurs, Marijke, Gruben, Nanda, Stienstra, Rinke, Shiri‐Sverdlov, Ronit, Kloosterhuis, Niels J., de Bruin, Alain, van de Sluis, Bart, Koonen, Debby P.Y., Hofker, Marten H.

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Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates von Shiri-Sverdlov, Ronit, Wouters, Kristiaan, Gorp, Patrick J. van, Gijbels, Marion J., Noel, Benoit, Buffat, Laurent, Staels, Bart, Maeda, Nobuyo, Bilsen, Marc van, Hofker, Marten H.

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