Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch von Hirobe, Sachiko, Azukizawa, Hiroaki, Hanafusa, Takaaki, Matsuo, Kazuhiko, Quan, Ying-Shu, Kamiyama, Fumio, Katayama, Ichiro, Okada, Naoki, Nakagawa, Shinsaku

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The K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumors von Sakamoto, Kotaro, Lin, Bangzhong, Nunomura, Kazuto, Izawa, Takeshi, Nakagawa, Shinsaku

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Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy von Ishimoto, Kenji, Konishi, Yuma, Otani, Shuichi, Maeda, Soya, Ago, Yukio, Hino, Nobumasa, Suzuki, Masayuki, Nakagawa, Shinsaku

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Intravenous Administration of Polyethylene Glycol-Coated (PEGylated) Proteins and PEGylated Adenovirus Elicits an Anti-PEG Immunoglobulin M Response von Shimizu, Taro, Ichihara, Masako, Yoshioka, Yasuo, Ishida, Tatsuhiro, Nakagawa, Shinsaku, Kiwada, Hiroshi

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(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism von Ago, Yukio, Tanabe, Wataru, Higuchi, Momoko, Tsukada, Shinji, Tanaka, Tatsunori, Yamaguchi, Takumi, Igarashi, Hisato, Yokoyama, Rei, Seiriki, Kaoru, Kasai, Atsushi, Nakazawa, Takanobu, Nakagawa, Shinsaku, Hashimoto, Kenji, Hashimoto, Hitoshi

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The VIPR2-selective antagonist KS-133 changes macrophage polarization and exerts potent anti-tumor effects as a single agent and in combination with an anti-PD-1 antibody von Sakamoto, Kotaro, Kittikulsuth, Wararat, Miyako, Eijiro, Steeve, Akumwami, Ishimura, Rika, Nakagawa, Shinsaku, Ago, Yukio, Nishiyama, Akira

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Analysis of Skin Permeability and Toxicological Properties of Amorphous Silica Particles von Matsuo, Kazuhiko, Hirobe, Sachiko, Okada, Naoki, Nakagawa, Shinsaku

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Solution of the structure of the TNF-TNFR2 complex von Mukai, Yohei, Nakamura, Teruya, Yoshikawa, Mai, Yoshioka, Yasuo, Tsunoda, Shin-ichi, Nakagawa, Shinsaku, Yamagata, Yuriko, Tsutsumi, Yasuo

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Performance and characteristics evaluation of a sodium hyaluronate-based microneedle patch for a transcutaneous drug delivery system von Hiraishi, Yasuhiro, Nakagawa, Takeshi, Quan, Ying-Shu, Kamiyama, Fumio, Hirobe, Sachiko, Okada, Naoki, Nakagawa, Shinsaku

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Improved Bioavailability of β-Carotene by Amorphous Solid Dispersion Technology in Rats von OTANI, Shuichi, MIKI, Shohei, NAKAMURA, Yuta, ISHIMOTO, Kenji, AGO, Yukio, NAKAGAWA, Shinsaku

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A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens von Matsuo, Kazuhiko, Yokota, Yayoi, Zhai, You, Quan, Ying-Shu, Kamiyama, Fumio, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku

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Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza von Matsuo, Kazuhiko, Hirobe, Sachiko, Yokota, Yayoi, Ayabe, Yurika, Seto, Masashi, Quan, Ying-Shu, Kamiyama, Fumio, Tougan, Takahiro, Horii, Toshihiro, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku

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ADMET Analysis of Amorphous β-Carotene and Its Usefulness Evaluation von Nakagawa, Shinsaku

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A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke von Yamazawa, Toshiko, Kobayashi, Takuya, Kurebayashi, Nagomi, Konishi, Masato, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U., Nishino, Ichizo, Mori, Shuichi, Iinuma, Hiroto, Manaka, Noriaki, Kagechika, Hiroyuki, Uryash, Arkady, Adams, Jose, Lopez, Jose R., Liu, Xiaochen, Diggle, Christine, Allen, Paul D., Kakizawa, Sho, Ikeda, Keigo, Lin, Bangzhong, Ikemi, Yui, Nunomura, Kazuto, Nakagawa, Shinsaku, Sakurai, Takashi, Murayama, Takashi

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Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis von Kitakami, Ryota, Inui, Kishin, Nakagawa, Yusuke, Sawai, Yurika, Katayama, Wakana, Yokoyama, Takeshi, Okada, Takuya, Kanamitsu, Kayoko, Nakagawa, Shinsaku, Toyooka, Naoki, Mizuguchi, Mineyuki

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Development and Clinical Study of a Self-Dissolving Microneedle Patch for Transcutaneous Immunization Device von Hirobe, Sachiko, Azukizawa, Hiroaki, Matsuo, Kazuhiko, Zhai, You, Quan, Ying-Shu, Kamiyama, Fumio, Suzuki, Hiroshi, Katayama, Ichiro, Okada, Naoki, Nakagawa, Shinsaku

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Clinical study of a retinoic acid-loaded microneedle patch for seborrheic keratosis or senile lentigo von Hirobe, Sachiko, Otsuka, Risa, Iioka, Hiroshi, Quan, Ying-Shu, Kamiyama, Fumio, Asada, Hideo, Okada, Naoki, Nakagawa, Shinsaku

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Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application von Nabeshi, Hiromi, Yoshikawa, Tomoaki, Matsuyama, Keigo, Nakazato, Yasutaro, Matsuo, Kazuhiko, Arimori, Akihiro, Isobe, Masaaki, Tochigi, Saeko, Kondoh, Sayuri, Hirai, Toshiro, Akase, Takanori, Yamashita, Takuya, Yamashita, Kohei, Yoshida, Tokuyuki, Nagano, Kazuya, Abe, Yasuhiro, Yoshioka, Yasuo, Kamada, Haruhiko, Imazawa, Takayoshi, Itoh, Norio, Nakagawa, Shinsaku, Mayumi, Tadanori, Tsunoda, Shin-ichi, Tsutsumi, Yasuo

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Generation of KS-133 as a Novel Bicyclic Peptide with a Potent and Selective VIPR2 Antagonist Activity that Counteracts Cognitive Decline in a Mouse Model of Psychiatric Disorders von Sakamoto, Kotaro, Chen, Lu, Miyaoka, Tatsunori, Yamada, Mei, Masutani, Teruaki, Ishimoto, Kenji, Hino, Nobumasa, Nakagawa, Shinsaku, Asano, Satoshi, Ago, Yukio

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Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors von NAGANO, KAZUYA, IMAI, SUNAO, ZHAO, XILULI, YAMASHITA, TAKUYA, YOSHIOKA, YASUO, ABE, YASUHIRO, MUKAI, YOHEI, KAMADA, HARUHIKO, NAKAGAWA, SHINSAKU, TSUTSUMI, YASUO, TSUNODA, SHIN-ICHI

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